| (the most recent research is at the top) |
| Financier |
Understanding virus replication is key to design antiviral drugs |
| Financier |
Molecular RNA switches that control HIV-1 replication |
| Financier |
Spatial and temporal regulation and function of Epac1 |
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Molecular Complexity and Diversity by Multicomponent Reaction Design |
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Formation of synthetic fuel: new insights! |
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The role of the Atg9 reservoirs in the autophagosome biogenesis |
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Enzyme inspired transition metal catalysis |
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PsbS makes the non-photochemical quenching work, but how |
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The first picoseconds of photosynthesis studied in vivo in individual (stressed) chloroplasts |
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Analysis of the dual functional ScbA, a small molecule synthase and regulator in the antibiotic producing bacterium, Streptomyces coelicolor |
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Novel density-matrix response functional theory to calculate molecular electronic excitations including double, bond breaking, and charge-transfer excitations |
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Casting a different light on bacterial cell wall synthesis |
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Cooperative and Redox Non-innocent Ligands in Hydrogenation, Dehydrogenation and Dehydrogenative Coupling Reactions |
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The complete experiment: Full 3D Quantum Imaging of a Photochemical Reaction |
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Cool molecules: unraveling the secret of anti-freeze proteins |
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Mechanism of Fischer-Tropsch Synthesis on an Iron Carbide Surface |
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Regulation of virulence factors in Pseudomonas aeruginosa: the surface connection |
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Remote control of intracellular zinc using light-regulated protein switches |
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Balancing bilayer and non-bilayer lipids in yeast: mechanism and players |
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Microreactors, containing controlled amounts of supported organic and nanometallic catalysts, as efficient vehicle to study organic reactions |
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Influence of wall roughness and particle adhesion on confined flows |
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Recognition of picornaviruses by RIG-I like receptors (RLRs), a novel class of cytosolic RNA sensors, in human cells |
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Supramolecular polymers at surfaces; chain-inversion symmetry and surface forces |
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Nanoalloys: the ultimate promoters for photocatalysis |
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The structural basis of DNA binding specificity within a transcription factor family |
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Bacterial ATP binding cassette (ABC) transporters for vitamin uptake with shared energizing modules |
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Positive control of cell division: from new concepts to molecular detail |
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The regulatory role of Ubl domains in ubiquitin specific protease function |
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Life and the Chemistry of Oxygen |
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Exploration of the cotranslational folding of a ribosome-bound alpha-beta parallel protein |
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Self-replication driven by self-organisation |
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Cytochrome bd oxidases: From molecular mechanism to cellular function |
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rotein semi-synthesis and evaluation of post-translational modified nuclear receptor domains |
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Zooming into large assemblies: A versatile incorporation of experimental data into biomolecular docking |
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Gene targeting tools for tissue-specific protein purification and analysis of the LIN-5 NuMA cell-division complex |
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Synthetic methodology for well-defined ADP-ribosylated biomolecules |
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Oxido-Reductases as Single Molecules |
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Automated solid phase synthesis of teichoic acids |
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In-Situ Spectroscopy of a Single Catalyst Particle: New Insights in Zeolite-based Bifunctional Catalysis |
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Telling right from left: enantioselective characterization of biomolecules in complex mixtures |
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Catalytic control over soft matter |
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Chiral pentaorganosilicates |
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Colloidal Surfactants (and beyond) |
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Molecular Machines at Work in the Gas Phase |
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In situ spectroelectrochemistry of outer membrane cytochromes embedded in living microorganisms grown on electrodes |
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Ultrafast spectroscopy linking molecular and device properties of organic solar cells |
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Combining ultrasmall with ultrafast: STM with sub-nanosecond time resolution |
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Multispectral nanomaterials for image guided surgery |
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Direct Activation of Oxygen by Early Transition Metal Complexes: From Fundamental Science to Application in Oxidation Catalysis |
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From Molecules to Crystals: Understanding the Key Factors that Govern the Observation of Crystal Structures |
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Getting a grip on microbial sialic acids in the human gut |
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Growing microtubule ends: cellular catalyzers of conformational changes |
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Engineering of methylaspartate ammonia lyase for synthesis of unnatural amino acids |
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The Art of Catching and Probing Single Molecules |
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Illuminating Biophotonic Switches |
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Characterization of a ceramide sensor controlling mitochondrial apoptosis |
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Chiral purification of racemic compounds: a grinding approach |
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Mechanocatalysis |
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Peptide Synthesis: An Essential Tool for Chemical Biology |
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Fluorescence monitoring of organocatalytic events |
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Cyclitol-fused 1-H-Imidazoles and Triazoles : a new mechanism-based class of glycosidas |
| Financier |
Mechanochemical probes of supramolecular polymer networks |
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A systems chemistry approach to self assembly and self replication |
| Financier |
Towards accurate predictive calculations on reactions of molecules on metal surfaces |
| Financier |
Enhanced photoswitchable fluorescent proteins for quantitative single-molecule microscopy in the living cell |
| Financier |
Presenting the Thiolome: proteome-wide quantification of cysteine oxidation and identification of redox-mediated protein-protein interactions. |
| Financier |
Breaching the epigenetic barrier: Towards complete reprogramming of human cells by Wnt-mediated stabilization of naïve pluripotency |
| Financier |
Initiation of DNA mismatch repair |
| Financier |
The crystal structure of the adenosine A2A receptor: the follow up |
| Financier |
Capture and Release of Polypeptides by the Bacterial Translocation Pore |
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Water-Water Pickering Emulsions |
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Slippery when wet: How water lubricates molecular machines |
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Catalytically active synthetic polymers in water by compartmentalization through folding |
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Novel Spintronic Materials |
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Understanding the origin of chirality in colloidal liquid crystals |
| Financier |
Novel Functional Molecular Materials Based on Phosphorus |
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Bio-inspired molecular rectifier for artificial photosynthesis |
| Financier |
Sweet attachment: structural and biological consequences of viral adaptation to specific sialic acid receptor determinants |
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Novel tools for computational spectroscopy: The primary isomerisation in vision |
| Financier |
Synthesis of Crenarchaeol, the Most Abundant Organic Compound on Earth |
| Financier |
Analysing of cis- and trans-acting factors in TSWV transcription |
| Financier |
Nanoscale Surface Analysis using X-ray Photoelectron Spectroscopy |
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Fingerprints in chemical biology: focusing on mass and shape |
| Financier |
Mass spectrometry for identifying supramolecular complexes |
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Giving a pulse to supramolecular chemistry in Twente |
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Nuclear Tomographic Scanner (NuTS) for Multiphase & Granular Flow |
| Financier |
Basic Research Equipment for Molecular Chemistry in the New Center for Life |
| Financier |
Multi-mode confocal microscope for exploring single-molecule protein folding, protein complex assembly, and transcriptional dynamics |
| Financier |
Micro-scale protein purification and characterisation workstation for protein structural biology |
| Financier |
From sunlight to fuel: a versatile all-timescale spectrophotometer to assess solar energy conversion in artificial photosynthetic devices |
| Financier |
Rapid analysis in asymmetric catalysis, total synthesis and systems chemistry |
| Financier |
Calorimetry for self-assembly of (bio)functional molecules and materials |
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Understanding the bottlenecks in membrane protein biogenesis |
| Financier |
Nidovirus deubiquitinating proteases: viral double edged swords |
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Viral RNA polymerases: the error paradox at the single-molecule level |
| Financier |
Probing the evolution of a molecular process using diffraction of photo-ionized electrons |
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Picoliter droplets to mimic the chemical environment within cells |
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Kinetically controlled peptide-polymer artificial organelles |
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Towards in-situ structural biology: Mapping folding and functional landscapes of cellular machines |
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Nanowire Growth |
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Well-defined gradient responsive copolymers: Design, synthesis and applications |
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Tough and smart: physically cross-linked double polymer networks |
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Metallic nanostructures from molecular patterns: Going beyond the limits of lithography |
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Modeling excited state dynamics in large molecular aggregates |
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Chemical and chemical-biology based approaches towards new lipid II targeting antibiotics |
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Understanding bio(mimetic) mineralization |
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Molecular mechanism of a chemical signaling via natively unfolded protein regions |
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Sister chromatid cohesion: lessons from yeast, mice and men |
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Role of Chemokine Gradient Sensing in Ewing's Sarcoma Progression, Angiogenesis and Immune Targeting |
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Plant-mediated interactions between two herbivores: from molecular mechanisms to community ecological consequences |
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Evolutionary systems biology and molecular networks linking nutrient status to growth |
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From surface-supported supramolecular assemblies to covalently coupled nanostructures |
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In-depth enabling proteomics technologies enhancing the understanding of adult stem cell differentiation |
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Nanostructured super-reflectors: learning lessons from scarab beetles |
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Computer-simulation in the design of nanoporous materials |
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Looking over the painter's shoulder with T-rays and X-rays |
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Kinetics in Soft Molecular Layers - from interstellar ices to polymorph control |
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Structure-dependency of non-coding regulatory RNA elements, an in vivo SELEX approach |
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Identifying distant functional regulatory elements in development using high-resolution 4C |
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Cholesterol pump in the vascular wall |
| Financier |
Molecular materials and nanosystems, in particular for solar cells |
| Financier |
Bioinspired Dry Adhesives from Block Copolymers |
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A tunnel vision on heterogeneous catalysis in water |
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Add and Mix: Bioconjugates to Solubilise Inhibitors |
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Target Residence Time |
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Targeted agents for multimodal in vivo imaging |
| Financier |
Protein Motions Revealed by Paramagnetic NMR Spectroscopy |
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Enhancement of fluorescence by self-assembly of metal nanoparticles on tagged biomolecules |
| Financier |
Vibrational Circular Dichroism: Towards a reliable and versatile method for absolute configuration determination |
| Financier |
Building the Renewable Lignin Platform: New Heterogeneous Catalyst Technology for the Production of Chemicals and Fuels from Biomass |
| Financier |
Visualisation and characterisation of dynamic protein folding events in vivo |
| Financier |
Ballistic electronics in graphene: Clearing the way for electrons in one atom thick carbon |
| Financier |
Quantum Pathways to Photosynthesis - Purpose-Driven Theoretical Chemistry for the Artificial Leaf |
| Financier |
The mechanic characteristics of bone, teeth and shells |
| Financier |
DNA and Nucleic Acid/Polymer Hybrid Materials for Diagnostics and Biomedicine |
| Financier |
Artificial molecules at the nanoscale |
| Financier |
Exploiting quantum interference effects in molecular scale electronics |
| Financier |
Electronic density functional theory for strong-interacting systems |
| Financier |
Zwitterionic oligosaccharides: charging the immune system |
| Financier |
Supra-fibrillar amyloid assemblies: Implications for cytoskeletal functioning |
| Financier |
Quick purification of protein complexes for structural proteomics, using single walled carbon nanotubes |
| Financier |
How proteoglycan receptors affect antigen cross-presentation and immunity |
| Financier |
Dynamics of wrapped DNA: study of nucleosome mobility and condensation by nuclear magnetic resonance |
| Financier |
Unidirectional energy transfer and charge separation in structured quantum-dot solids |
| Financier |
New catalysts for water oxidation by rational design |
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Hitting the right spots: Integrative structure-based virtual screening against intended and undesired protein drug targets |
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Development of a polarizable force field for general use in biomolecular simulation |
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NEXT CAT-HOIF: designing the NEXT generation of CATalytic Hybrid Organic Inorganic Frameworks |
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Polymer superstructures through folding-templated assembly |
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Kondo-Effects Induced by Self-Assembled Organic-Inorganic Nanostructures on Thin Metal Films |
| Financier |
Biogenic hybrid materials for novel functionality |
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Elucidation of structure function relationships of Arabidopsis PIN proteins |
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Breathing through a wire: electro-enzymology of Q-wired respiratory complexes |
| Financier |
Pan-DUB inhibitors to delineate DUB dependent biology and tools to study the ubiquitinated proteome |
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Cutting it down to size |
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Polarity of Charged Quantum Dots |
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Structure determination of sub-micron three-dimensional crystals of proteins and other highly radiation sensitive materials by electron diffraction |
| Financier |
Self-Assembling Interpenetrating Networks |
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Imaging the Molecular Dynamics of H2O and OH |
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Developmental glycosylation of schistosomes analysed in relation to host immunity |
| Financier |
Molecular mechanism of signaling and sensing of membrane properties by a bacterial thermosensor |
| Financier |
Protein Network Dynamics |
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Mechanism of gene-selective initiation of transcription by TBP and TBP2 |
| Financier |
Cold molecules by a hot chemical kick |
| Financier |
The plant compass: dynamic AGC kinase signalling complexes that orient development by directing auxin transport |
| Financier |
Stability of confined water layers in hydrophobic nanochannels |
| Financier |
Determining and modelling the effects of genomic variation on phenotypic diversity |
| Financier |
Hijacking of human receptor proteins by human cytomegalovirus-encoded GPCRs |
| Financier |
Bioorthogonal Reactions for Neoglycoprotein Preparation and Glycoprofiling |
| Financier |
Hanging by a thread; how do proteins recognize collagen in hemostasis and immune cell suppression? |
| Financier |
Engineering nucleophile selectivity of halohydrin dehalogenase |
| Financier |
Self-assembly of alpha-synuclein across length scales |
| Financier |
How Photosynthetic Membranes Switch |
| Financier |
Probing molecular dynamics by illuminating molecules with x-ray free electron lasers |
| Financier |
Energy from streaming potential using nanotechnology |
| Financier |
Self-assembled oxidic mesostructures |
| Financier |
Dynamics of Protein Complexes by Spin and Light |
| Financier |
Bioinspired Supramolecular [NiFeS]-Metalloporphyrin Assemblies for the Photocatalytic Production of Dihydrogen |
| Financier |
DNA Block Copolymers: Preparation of Novel Architectures and Applications of Thermo-Responsive Conjugates |
| Financier |
Stereocontrol of glycosylations by oxacarbenium ions |
| Financier |
Understanding heat- and surface effects for zeolite membranes |
| Financier |
Electrostatic manipulation of light-alkane oxygenation at low temperature |
| Financier |
Molecular Imaging using targeted MR1 contrast agents |
| Financier |
Microreactor time-resolved operando spectroscopy for kinetic analysis of (ultra)fast reactions |
| Financier |
Chemical challenges for construction of protein mimics: from synthetic vaccines to synthetic antibodies |
| Financier |
Catalysis at the Nanoscale |
| Financier |
Visualisation of the encounter state of protein complexes |
| Financier |
Translational motion in individual motor molecules |
| Financier |
The role of water in the structural dynamics of proteins |
| Financier |
The photolyase/cryptochrome protein family: delineating structures and functions |
| Financier |
The +RNA virus replication and transcription complex: hijacking membranes to accommodate viral RNA synthesis in the cytoplasm |
| Financier |
Synthetic tools to interfere with glucosylceramide metabolism: fundamental studies and therapeutical apllications |
| Financier |
Structural and biophysical characterisation of Rap-GEFs |
| Financier |
Signaling mechanisms regulating membrane recycling from endosomes |
| Financier |
Role of secretory pathway membranes in enterovirus genomic RNA replication |
| Financier |
piRNA Biogenesis in Zebrafish |
| Financier |
On the Chemical Biology of Mycobacterial Lipids |
| Financier |
Novel Nanomaterials: Towards Functional Nanowalls |
| Financier |
Novel mechanisms in bacterial cell division: an integrated approach to unravel the septum localising complex of streptomycetes |
| Financier |
New nisin-based hybrid peptide antibiotics by semisynthesis |
| Financier |
Molecular origin of thermodynamically stable Pickering emulsions |
| Financier |
Molecular Movies of Protein Folding |
| Financier |
Molecular mechanism of regulated light harvesting |
| Financier |
Microcalorimetry: Towards thermodynamics based drug design |
| Financier |
Membrane Attack Complex - Complex formation and membrane perforation |
| Financier |
Love can cross any border: unusual affairs between aminoglycosides and oligonucleotides |
| Financier |
Lineactants - Colloid Stability in Flatland |
| Financier |
Light-Driven Dihydrogen Production in [2Fe2S]-Metalloporphyrin Supramolecular Assemblies |
| Financier |
Histone methylation and transcription: Writing and Reading of the code |
| Financier |
Fundamental studies on catalyst preparation using nanostructured support materials |
| Financier |
Functional Mimicry of Discontinuous Protein Binding Sites using a Combination of CLIPS-technology and CLICK-chemistry |
| Financier |
Functional Adaptive Supramolecular Systems for Medical Applications |
| Financier |
Dynamic molecular DNA linkers: exploring the role of SMC proteins in chromosome organization |
| Financier |
Direct epoxidation of propene in a microreactor |
| Financier |
Crystals of crystals of nanocrystals |
| Financier |
COMPLEX IONS - searching for a missing link in astrochemistry |
| Financier |
An alternate mechanism for methane conversion |
| Financier |
A novel type of ubiquitination regulates apoptosis signaling by BH3-only protein Bid. |
| Financier |
Conformational transitions of initiation factor IF2 in functional states of bacterial protein synthesis |
| Financier |
Moving Assemblies |
| Financier |
Proteins out of isolation: simulating the influence of the environment on polypeptide self-assembly |
| Financier |
Unveiling the invisible conformational landscape of cytochrome P450 |
| Financier |
Functional polymersomes: from artificial organelles to cascade reactors |
| Financier |
Generation of Supramolecular Functional Cavities - Container Molecules, Macrocycles and Related Compounds |
| Financier |
How do proteins communicate? Predicting function, formation and interactions of coiled coil complexes at the molecular level |
| Financier |
Atom Control of Liquid Phase Epitaxy |
| Financier |
Mechanistic insight into catalytic and photo-catalytic systems based on novel porphyrinoids by scanning probe |
| Financier |
Structural analysis of translesion synthesis DNA repair |
| Financier |
It's good to be flexible: taking protein flexibility in structure-based drug design to the next level |
| Financier |
In vivo magnetic resonance spectroscopy of lipid dynamics in insulin-resistant muscle |
| Financier |
Cracking the SUMO Code by Mass Spectrometry |
| Financier |
Composition, function, and dynamics of the yeast nuclear envelope |
| Financier |
Paramagnetic tracking of substrates through cytochromes P450 |
| Financier |
Spatial chromatography |
| Financier |
Tailoring the Active Site: Unique Phosphorus Heterocycles for Homogeneous Catalysis |
| Financier |
Digitalis-like compounds: new molecular interactions of an ancient arrow poison |
| Financier |
Single Molecule Enzymology |
| Financier |
Formation mechanisms of key astrochemical ice components |
| Financier |
Size matters: Native mass spectrometry to study intact protein complexes involved in viral genome packaging and storage |
| Financier |
Microinterface techniques for coupling of capillary gas chromatography-mass spectrometry to biological assays |
| Financier |
Electrochemistry in fluidic nanodevices: exploring the single-molecule limit |
| Financier |
An Inside Look at Dynamics in Biological Membrane Models |
| Financier |
What is the structural basis for the binding of amyloid peptides to tissue-type plasminogen activator? |
| Financier |
Vesicle trafficking dynamics in polarized cell growth |
| Financier |
Unravelling hidden secrets of the master of genetic engineering , the bacterium Agrobacterium tumefaciens |
| Financier |
Unraveling atomic layer deposition of oxides using multi-quantum and multi-photon vibrational spectroscopies |
| Financier |
The Molecular Machinery of Genome Maintenance: Functional Architecture and Dynamics |
| Financier |
Switching biological activity through conformational control: "silencing" peptides. |
| Financier |
Silica-based nanoparticles for magnetic resonance and optical molecular imaging |
| Financier |
Probing the dynamics of surface-catalyzed reactions with scanning noise microscopy |
| Financier |
Organophosphorus Building Blocks |
| Financier |
Molecular systems for Smart Responsive and Catalytic Surfaces |
| Financier |
Macromolecular Nanotechnology with Stimulus Responsive Polymers |
| Financier |
Infrared spectroscopy of ultrafast dynamics in complex systems |
| Financier |
In-situ X-ray spectromicroscopy of nanoparticle-adsorbate interactions |
| Financier |
Functional and structural characterisation of an ESAT-6-like protein secretion system |
| Financier |
Enzymes in action: Fluorescence monitoring of single redox enzyme molecules. |
| Financier |
Coupled affinity extraction - capillary electrophoresis for profiling of phopsphorylated sugars in genetical metabolomics |
| Financier |
Computational Reactor Engineering for Sustainability (CoRE-S) |
| Financier |
Catalytic Communication, coupling Motion and Function |
| Financier |
A multifunctional genome-wide screen to unravel the roles of the conserved epigenetic regulator Dot1 in chromosome organization |
| Financier |
The molecular basis of long-range beta-globin activation |
| Financier |
Adaptive Multi-scale Molecular Dynamics for the Study of Hydrogen Production and Chemistry in Water |
| Financier |
Mechanism of gene-regulation by YY1 & Polycomb-group proteins in development and disease |
| Financier |
Combining quantitative proteomics and genomics to elucidate cell signalling through Cdk8 |
| Financier |
Energy transport in model membrane proteins |
| Financier |
Dynamic structure formation of colloids in confined geometries |
| Financier |
Structural Effects of Radiation Damage to Biomolecules |
| Financier |
Manipulating the MHC class II system to control immune responses in autoimmunity |
| Financier |
Isolation and Characterisation of Native Receptor Complex Components |
| Financier |
Identification of proteins that regulate intraflagellar transport |
| Financier |
Herpes Simplex Virus: Feeling protein interactions, Hearing conformational changes & Seeing genome delivery |
| Financier |
New approaches for accurate and efficient macromolecular crystal structure solutions |
| Financier |
Multiscale modeling of photo-active proteins |
| Financier |
Realizing a dream in nanoscience: Relating the atomic landscape to the local electronic spectrum by integration of scanning probe microscopy and tunneling spectroscopy in ultra-high vacuum. |
| Financier |
Microbiology and mechanisms of exocellular electron transfer in microbial fuel cells |
| Financier |
Combined solution and solid-state NMR study of yeast membrane proteins Hor7p and Pmp3p: A structural approach to unravel the molecular basis of salt tolerance |
| Financier |
Development of low-energy electron scattering theory for molecules with time-dependent density-functional theory: Application to radiation damage of DNA |
| Financier |
Inclusion of nanoparticles in watersoluble reversible coordination polymer networks |
| Financier |
Integral Microreactor System: Probing the Performance of Heterogeneous Catalysts under Realistic Conditions in Liquid and Multiphase Systems |
| Financier |
Exploiting catalytic promiscuity: the tautomerase superfamily active site as a scaffold for new biocatalysts |
| Financier |
Semi-synthetic multivalent peptides and proteins |
| Financier |
Modulation of protein kinase function by the lipid second messenger phosphatidic acid |
| Financier |
Synthetic Nucleotidylated Proteins |
| Financier |
Nanostructured composite materials for hydrogen storage |
| Financier |
Natively unfolded proteins, aggregation and disease |
| Financier |
Electronic coupling between nanocrystal building blocks studied with ultimate spatial resolution |
| Financier |
Charge-Transfer dynamics in O2-X clusters |
| Financier |
In-situ optical spectroscopy of a single metal nanoparticle in catalytic action |
| Financier |
Regulation of the glycosylated epithelial calcium channel by N-glycan hydrolysis |
| Financier |
How is von Willebrand factor regulated by shear stress? |
| Financier |
Gene regulation by protein (de)ubiquitylating enzymes |
| Financier |
Metalloenzymes in action ? A computational study |
| Financier |
Time-resolved enantioselective phosphorescence: a novel approach for chiral detection in flow systems |
| Financier |
New synthetic methodology for biologically relevant nitrogen heterocycles. |
| Financier |
Ultracold controlled chemistry |
| Financier |
Optimal atoms and fragments in Valence Bond theory |
| Financier |
Scattering of highly vibrationally excited NO from Ag(111) and Cs/Ag(111): electronically adiabatic or not? |
| Secretariat |
Development of new dielectric materials for improving the quality of high field clinical magnetic resonance imaging. |
