KNAW

Organisation

Groningen Biomolecular Sciences and Biotechnology Institute - GBB

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Current research

(the most recent research is at the top)
Collaboration System-wide genetical genomics: From genome to phenotype in A. thaliana
Commissioner Bacterial ATP binding cassette (ABC) transporters for vitamin uptake with shared energizing modules
Secretariat A large Photosystem I supercomplex active in cyclic electron transport
Secretariat Computational Microscopy of Cellular Membranes
Secretariat Getting in shape: Coordinating cell-cycle events with cell wall synthesis and division in Streptococcus pneumoniae
Secretariat Breaking and entering: investigating peptide disruption of cell membranes
Secretariat A novel approach to single-molecule chemistry using semi-synthetic protein nanopores
Secretariat Experimental evolution of bet-hedging strategies for spore formation in Bacillus subtilis
Secretariat Informatics-driven drug discovery from microbial metabolites
Secretariat Carbohydrate-active enzymes active on bacterial capsular polysaccharides facilitate microbial competition in the human gastrointestinal tract.
Secretariat A general law describing the diffusion of membrane proteins based on single molecule tracking in live Escherichia coli
Secretariat Non-invasive 4D microscopy for bacteria: Real-time spatial imaging of stochastic events and regulator dynamics in live bacterial cells (4D-BAC)
Secretariat Photosystem II, a dynamic protein supercomplex
Secretariat Optimizing growth rate, biomass and product formation of Lactococcus lactis by a Systems Biology approach
Secretariat Lipid engineering and -modulation to improve protein secretion by Bacillus subtilis
Secretariat AntiBioScreen - Antimicrobial discovery in filamentous fungi
Secretariat Education and research on Synthetic Biology for Advanced Metabolic Engineering
Secretariat The rise of peroxisomes; towards the understanding of de novo peroxisome formation
Secretariat Electrochemically-assisted redox enzyme reactors by cofactor immobilization
Secretariat Hybrid Protein Models: Combining Accuracy & Speed
Secretariat Multiscale modeling of cellular membranes
Secretariat Paving the path for antibiotics killing dormant cells
Secretariat Exploring soft matter and protein structures by electron microscopy
Secretariat Small molecule modulators of essential transport functions in pathogenic bacteria
Secretariat Facility for a multi-purpose stopped-flow system to unravel enzyme kinetics
Secretariat Deciphering the role of Pex11 in peroxisome biology
Secretariat Analysis of the dual functional ScbA, a small molecule synthase and regulator in the antibiotic producing bacterium, Streptomyces coelicolor
Secretariat Capture and Release of Polypeptides by the Bacterial Translocation Pore
Secretariat Micro-scale protein purification and characterisation workstation for protein structural biology
Secretariat Understanding the bottlenecks in membrane protein biogenesis
Secretariat Harvesting the sun.... safely
Secretariat Analysis of the role of histone demethylases Jmjd2a and Jmjd2d in development and differentiation
Secretariat Cardiolipins and Respiratory Chain Supercomplexes
Secretariat Mapping epigenetic quantitative trait loci in Arabidopsis
Secretariat Getting in shape: The role of the conserved StkP/PhpP signalling couple of Streptococcus pneumoniae in coordinating cell wall synthesis with cell division
Secretariat The Silicon Trypanosome (Silico Tryp)
Secretariat Into the ring - Protein-protein interactions in bacterial cell division
Secretariat Protein Network Dynamics
Secretariat Engineering nucleophile selectivity of halohydrin dehalogenase
Secretariat Structure and mechanism of ABC transporters with integral membrane solute binding proteins
Secretariat Peroxisome research: the need for Fluorescence Activated Cell Sorting (FACS)
Secretariat Assembly and function of pili in gene transfer and biofilm formation in Sulfolobus solfataricus
Secretariat Evolutionary reconstruction of energy conservation mechanisms to decarboxylation pathways in Lactic Acid Bacteria
Secretariat Composition, function, and dynamics of the yeast nuclear envelope
Secretariat Metabolomic systems biology: from numbers to networks
Secretariat NMR methods for the study of protein electrostatics
Secretariat Dynamic protein refinement using dipolar couplings
Secretariat Structure determination by NMR
Secretariat Protein Dynamics from NMR spin relaxation: The neuronal tau protein
Secretariat NMR residue assignments for intrinsically unfolded proteins: high-dimensional data reconstruction from the acquisition of 2D projections
Secretariat NMR studies of large (> 30kDa) proteins and enzymes
Secretariat Structure and function of secondary transporters
Secretariat Transport processes in Penicillium chrysogenum
Secretariat Multidrug resistance
Secretariat Designer Lactococcus lactis as Improved Protein Production Suite
Secretariat Secretome Dynamics: transcriptional profiling of Secretome-encoding genes and subcellular localisation of Sec- and Tat-components of B.subtilis
Secretariat Competence development in Bacillus species
Secretariat Mechanosensitive channels
Secretariat ABC transporters
Secretariat Diffusional barriers
Secretariat Insilico Reconstruction of Metabolic Model of Streptomyces Coelicolor A3(2).
Secretariat Parallelization of novel algorithms in Gromacs
Secretariat Automation of EM Data Acquisition
Secretariat Respiratory chain supercomplexes in mitochondrial membranes
Secretariat ENZYME-II mannitol
Secretariat Structure of the luminal plasma membrane protein (uroplakin) complex from urinary bladder
Secretariat Two stators visualized in V-type ATPase
Secretariat Photosystem II complex from Arabidopsis
Secretariat Photosystem I in cyanobacteria
Secretariat Biocatalyst engineering for the production of semi-synthetic antibiotics
Secretariat Baeyer-Villiger monooxygenases as useful biocatalysts
Secretariat Bacterial degradation of dichloropropene and trichloropropane
Secretariat Biodegradation of halogenated pollutants
Secretariat Natively unfolded proteins, aggregation and disease

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