KNAW

Organisation

NWO Council for Chemical Sciences

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Completed research

(the most recent research is at the top)
Financier Solid-state nuclear magnetic resonance studies of NaAlHy-based hydrogen storage materials
Financier Design and synthesis of hybrid antibiotics targeting bacterial cell wall biosynthesis
Financier Three-dimensional electron microscopy of macromolecular assemblies: determination of mitochondrial supercomplex structures
Financier Instrumentation for characterization of interactions and molecular stability.
Financier High repetition rate laser system for cold quantum photochemistry
Financier Charged colloidal rods in suspension: screening, twisting, demixing, and ordering
Financier Mechanical switching of transition metal catalysts
Financier Kinetic Monte Carlo Modelling of The Initial Stages of Zeolite Synthesis
Financier Molecular nanoscale cell manipulation
Financier Identification of transcription factor- and gene-interactions of those WSTF- and ISWI-chromatin remodelling complexes that are important in regulating neural stem cell identity
Financier Facility for on-line product detection in selective electrocatalysis
Financier Dimeric ligands for GPCRs involved in human reproduction: synthesis and biological evaluation
Financier New directors in the cell division orchestra: coordinating multiple septation and chromosome segregation in filamentous streptomycetes
Financier Damage recognition in nucleotide excision repair
Financier Peptide-polymer hybrid coatings with antibiotic activity
Financier A protein-based artificial solar antenna derived from biological self-organization principles
Financier The palladium diphosphane catalyzed reduction of nitrobenzene
Financier LC-MS analysis for synthetic studies, in particular cyclic peptides.
Financier Diversity through generality
Financier Regulation and modulation of ion transport across membranes in neuronal and muscle cells
Financier The amazing electronic effects at oxide interfaces
Financier Pentaalkyl fullerene ligands for low valent transition metals: synthesis, reactivity and application in nano-chemical devices
Financier Towards Selective Organometallic Mediated Amination of Alkenes with Ammonia
Financier Controlled Solvent Induced Shuttling in Molecular Motors in the Gas Phase
Financier Expression and Control of Chirality in Self-Assembled Nanostructures of Cyclic Dipeptides
Financier Manganese-enhanced MRI of migraine mice:in vivo evaluation of calcium channel functioning
Financier Rational microporous materials synthesis using ionic liquids
Financier Liquid-liquid microreactors for phase transfer catalysis
Financier Coordinated SecA motor and SecYEG channel opening mechanisms during protein translocation
Financier Optimal designs for social, behavioural and biomedical research
Financier Functionalized Membranes for Sustainable Process Applications
Financier Viral hemagglutinin-esterases: mediators of dynamic virion-glycan interactions
Financier Folding, production and assembly of viral complexes for high resolution structure analysis (FOLPROCOM)
Financier Surface patterning with hybrid beta-sheet block copolymers
Financier Synthesis and Analytical Centrifugation of Magnetic Model Colloids
Financier The role of co-factor binding in sorting of authentic peroxisomal matrix proteins
Financier Tuning Rare-Earth Metallocenes for Catalytic Organic Transformations: C-H Activation and C-C bond formation
Financier Coronavirus RNA synthesis: how to handle errors, stops and jumps while replicating the largest RNA genome.
Financier Biochemical profiling of the oncogenic signaling network induced by the cytomegalovirus-encoded receptor US28
Financier Towards quantitative functional metalloproteomics using multiple short-lived metal-isotopes
Financier High throughput screening of membrane topology for structural classification of membrane proteins
Financier NOVEL BORONATED POLYAMIDOAMINES AS MULTIFUNCTIONAL VECTORS FOR siRNA DELIVERY
Financier From sweet to bitter: glycan-induced immunopathology in schistosomiasis
Financier Analysis of the interaction partners of the transcription factor GATA2
Financier Visualizing the Telomerase Molecular Motor Extend the Ends of DNA
Financier Carbon nanofiber layers on metal and carbon substrates. PEM fuel cell and microreactor applications
Financier Orthogonal supra-molecular interaction motifs for functional monolayer architectures
Financier Real-Time Visualization of DNA-protein transactions during DNA Recombination: Analysis of Mechanistic Dynamics on Single DNA Molecules
Financier Molecular Assembly with Macro-ions
Financier Effect of colloidal and interfacial properties of elemental sulphur produced by biological oxidation on the process of removal of H2S from natural gas
Financier Electroluminescent materials based on metal complexes
Financier Elementary processes in enzyme reaction dynamics
Financier The effects of urea and of pH on protein structure
Financier Bifunctional metal complex binding to DNA: medicinal aspects
Financier Proteomic analysis of the histone code and chromatin-modifying and -binding protein complexes
Financier L1 and Alu elements: structural and functional analysis of human non-LTR retrotransposons
Financier Cytomegalovirus-encoded receptors as modulators of cellular signalling networks
Financier Structure and domain formation in ferroelectric thin films
Financier Illuminating Coronavirus-Host Interactions
Financier Real-space imaging and manipulation of chemical reactions at solid-liquid interfaces
Financier Opto-electrical properties of quantum-dot molecules and solids
Financier Structural and functional characterization of two-partner secretion systems of pathogenic Gram-negative bacteria
Financier The structure of microtubule plus end binding proteins and their influence of microtubule dynamics
Financier Directed evolution of a novel dehalogenating activity in the short-chain dehydrogenase/reductase family
Financier Design and selection of biocatalysts for amination reactions
Financier Molecular redesign of Baeyer-Villiger monooxygenases. Understanding and improvement of their biocatalytic properties
Financier Combinatorial RNAi against HIV-1
Financier Bio-organic nanostructuring for molecular electronics (BIONICS)
Financier Assembly and Manipulation of Functional Supramolecular Nano-Architectures at surface (FUN-SMARTSs)
Financier Nanoscale Electrical Transport in Self-Organized Molecular Assemblies (NETSOMA)
Financier Self-organized nanostructures: from colloidal liquid crystals to optical, magnetic and macroporous materials
Financier Self-replicating polymersomes
Financier Structural and functional characterization of DNA mismatch repair protein complexes
Financier Computational approach to new catalytic reactions: rates of surface reactions
Financier Fast hydrogen storage with transition metal oxides; better catalysts through defect chemistry
Financier Structural enzyme kinetics: studies on Chlorella DNA ligase
Financier Translational control by a molecular Trojan horse
Financier Unraveling the Cockayne syndrome B protein mechanism of action, at the crossroad between gene transcription, DNA repair and nucleosome remodeling
Financier Response properties for valence bond wavefunctions: theory and applications to transition metal complexes
Financier RNA pseudo-triloops: key structures in RNA-protein recognition and targets for potential drugs
Financier A Sustainable, Two-Enzyme, One-Pot Procedure for the Synthesis of Enantiomerically Pure a-Hydroxyacids
Financier Gene regulation by chromatin remodelling factors
Financier The outer membrane protein assembly machinery of Neisseria meningitidis
Financier Reactivity of cationic group 3 and lanthanide metal alkyl complexes
Financier Motors for use in molecular nanotechnology
Financier TEM-EELS tomography of nanostructured materials
Financier Highly mobile triphenylene based organogel networks
Financier Elastic templates for conducting nanotubes with tunable diameter
Financier Biochemistry of RNA interference in C. elegans
Financier Film formation by coalescence of water borne particle dispersion
Financier Improving protein crystals in high magnetic fields
Financier Dynamics in thin glass films probed by second-harmonic generation
Financier Electron microscopy of mitochondrial supercomplexes
Financier Stuctural studies on a secretion chaperone from shigella flexneri and crystallographic explorations with a thermostable aldolase
Financier ABC transporters. Lessons from a bacterial oligopeptide uptake system
Financier Quantum dynamics of chemical reactions
Financier Atomic force microscope for imaging under controlled environmental conditions
Financier Gas chromatograph/mass spectrometer for online monitoring of MOCVD chemistry
Financier Who's afraid of blue and (infra)red?
Financier A cryo-cooled NMR probe for structural biology
Financier High repetition rate, picosecond intensified CCD detector for efficient rejection of fluorescence in LC-Raman
Financier Generating Phosphinidenes: New Approaches
Financier Auxiliary-Mediated Synthesis of Cyclic Peptides
Financier Molecular characterization of a novel biosurfactant of Pseudomonas, which solubilizes polycyclic aromatic hydrocarbons and biofilms
Financier Semiconductor photonic materials
Financier Adsorbate interactions in the kinetics of surface reactions of small molecules
Financier Biomimetic templates for the controlled fabrication of organic-inorganic hybrid materials
Financier Oxidative conversion of alkanes to olefins - mechanistic routes for product formation
Financier An ab initio study of ion solvation in water
Financier Origin and evolution of the mitochondrial proteome: applications for protein function prediction in the eukaryotes
Financier Capturing the rate of gene evolution and the timescale of mammalian evolutionary history
Financier Genes affecting triglyceride metabolism from steatosis to lipodystrophy
Financier Wageningen Phytoinformatics: the added value from plants
Financier Structural and biochemical characterization of the BRTC domains and their ligand interactions of the human breast cancer susceptibility gene 1 (BRCA1) protein
Financier Engineering of non-conventional architectures via supramolecular initiators
Financier Hybrid 2D and 3D Nanostructures using Multivalent Supramolecular Interactions
Financier Two-dimensional infrared spectroscopy of proteins
Financier The structural basis of glutamatergic neurotransmission
Financier Structural characterization of intact heterogeneous protein assemblies by mass spectrometry
Financier Non-covalent dendritic catalyst assemblies for homogeneous continuous-flow experimentation in organic synthesis
Financier Metalloenzymes from a high-frequency EPR/ENDOR perspective
Financier Lithium-ion dynamics in electrode materials
Financier A cryo-cooled NMR probe for structure-function studies of biomolecules at micromolar concentrations
Financier The second PAH domain of Sin3 - Structural biology & NMR methodology
Financier Chiropto-electronic properties of chiral p-conjugated polymers
Financier Cascade Polymerisation Reactions
Financier Oxacarbenium ion intermediates in the stereoselective synthesis of anionic oligosaccharides
Financier Understanding enzymatic function by advanced EPR
Financier Ultrafast dynamics of excitons and charge carriers in functional materials
Financier The biomimetic synthesis of CaCO3 biomaterials
Financier Single-enzyme electrochemistry at nanoelectrodes
Financier Synthesis and investigation of polypeptide rod-coil block copolymers for nanostructured materials
Financier The solid-state photo-cidnp effect
Financier Metabolomics and transcriptomics investigations into signal transduction processes controlling plant resource allocation
Financier Synthesis and Application of Nano-Structured Metal Catalysts
Financier Biochemistry and significance of P-type ATPase-dependent lipid transport
Financier (Macro)Molecular engineering on the nanoscale
Financier Polymeric micelles with transient stability: a novel and versatile drug delivery concept
Financier Protein imprinted nanoparticles (PINAPLES) as artificial antibodies
Financier Bridging the gap between natural & artificial light-harvesting
Financier Molecular analysis of a novel dechlorinating biocatalyst
Financier Conversion of chlorinated waste streams from the production of polyvinyl chloride over La-based catalysts
Financier Reactor concept for the selective oxidation of propane for olefin production
Financier Water soluble poly(ferrocenylsilanes): The fabrication of capsules with switchable permeability
Financier Femtosecond coincidence imaging
Financier Coherent control of molecular dynamics in complex systems
Financier Mechanisms of light activation in blue-light photoreceptors
Financier Comprehensive analysis of proteins regulating protein synthesis, folding, and transport during cellular differentiation
Financier Biochemistry of Tungstoenzymes from Pyrococcus furiosus
Financier Spectroscopic analysis of a translocase-entrapped preprotein
Financier Computational studies in actinide chemistry
Financier Electron-nuclear coupling in time-dependent multicomponent density functional theory
Financier Structure, function and evolution of small heat-shock proteins
Financier Framework for flexible data integration to support system biology
Financier Formation of novel macromolecular architectures by the controlled growth of polymers from well-defined and functional templates
Financier Synthesis and characterization of metallo-supramolecular materials - towards (block) copolymers utilizing combinatorial methods
Financier Mass spectrometric structural analysis of biological macromolecular complexes using chemical cross-linking
Financier Targets for the novel lipid second messenger, phosphatidic acid
Financier Metalloporphyrin molecular sieves as non-covalent catalyst support
Financier Synthesis, characterization and organization of nano-hybrid materials containing conjugated oligomers and metal rods
Financier Photo-CIDNP solid-state MR on oriented photosynthetic membranes revealing the spatial and electronic structure of the primary electron donors
Financier Intelligent biocatalysts: designing allosteric effects in enzymes
Financier Catalytic behaviour of Cu, Ag and Au nanoparticles
Financier Coincidence electron and ion imaging of femtosecond laser induced dynamics in atoms and molecules
Financier Gas-liquid phase transiton in charge-stabilised colloidal suspensions: a contradiction with DLVO theory
Financier Mureidomycin A and Dihydropyrimidine Nucleosides
Financier Modular synthesis of well-defined macromolecular architectures. Employment of “click” reactions in polymer chemistry
Financier Production and storage of hydrogen; a first principles approach
Financier Evolution of the antigen presentation system and pathogenic evasion
Financier Pincer-porphyrin hybrids: metalloporphyrins as catalyst modulating substituents
Financier Structural and Functional Analysis of Mammalian Cryptochromes -A Matter of Time
Financier Purchase of X-ray diffraction equipment (X-ray mirrors, image plate, nitrogen cryo-stream)
Financier Total synthesis of enantiopure biomolecules. On myclolactones, saturated isoprenoid building blocks and ß-mannosyl phosphomycoketides
Financier Nature Inspired Chemical Engineering (NICE)
Financier Theory of charge transport in pi-stacked systems including DNA
Financier Computers and drug discovery
Financier Educative application of parallel synthesis in homogeneous catalysis research
Financier Inorganic emulsion droplet templating
Financier Center for Scanning Force Microscopy: analysis of biological nanomachines
Financier Peptidomimetic ligands for the tandem SH2 domain of Syk kinase
Financier Transient interactions between photosynthetic proteins
Financier Self-assembly of functional polymers
Financier EPR and NMR Spectroscopy on Spin Labeled Proteins
Financier Hydrogen-bond stabilised columnar liquid crystal phases
Financier Synthesis studies of the zwitterionic polysaccharide PS A1, a major cause of human abdominal abscesses
Financier Enabling technologies for single molecule studies: from scientific curiosity to technological advance
Financier A combinatorial approach for homogeneous asymmetric catalyst development
Financier Three-dimensional structure determination of human lysosomal enzymes involved in glycosphingolipid breakdown
Financier Morphology and dynamics of gene delivering amphiphiles studied by NMR spectroscopy
Financier Structural and functional analysis of the human L1/Alu retroposition machinery
Financier Functional domains of RNA genomes of enteroviruses: structural aspects and biological significance
Financier Transport phenomena and the interaction of ionizable materials in water
Financier The synthesis of mycobacterial and archaebacterial lipids
Financier Cooperative Porphyrin Assemblies
Financier Reactivity of rhodium (II) and iridium (II) olefin complexes in activation of dioxygen and other substrates
Financier The Development of Supramolecular Ligand Libraries and their Application in Asymmetric Catalysis
Financier Structural analysis of the mechanism of ubiquitin conjugation, a generalized cellular addressing system, that controls protein and DNA stability
Financier Modelling of biomolecular complexes by data-driven docking
Financier Function of regulatory proteins controlling anthocyanin synthesis and vacuolar pH
Financier Electrocatalysis of nitric oxide reduction and oxidation at single-crystal electrodes
Financier The nanoprobe as a tool for solid-phase synthesis
Financier Spatio-temporal framework for integrative analysis of zebrafish developmental studies
Financier Architecture on the nanoscale - controlling the physico-chemical properties of carbon nanofibers
Financier Computational genomics of prokaryotes
Financier 14-3-3 proteins: novel regulators of the evolutionarily related chloroplast F1F0-synthase and vacuolar V1V0-ATPase
Financier Characterization of the evolutionarily conserved role of Escherichia coli YidC in membrane protein
Financier Novel Routes to Model Colloids: ellipsoids, latices and stable meso-emulsions
Financier Transient complexes of haem proteins
Financier Photoinduced Dynamics in OH, H2, and N2O
Financier Supramolecular catalysis: catalyst assembly, dynamic combinatorial catalysis and catalytically active nano-objects
Financier Continuation of CW support for National Centre for High Resolution Electron Microscopy
Financier Analysis of Genome-Scale Data
Financier Ring-closing metathesis of functionalized olefins: key to heterocyclic building blocks and natural products
Financier Ordered pattern formation and chaos-order transitions in pulsed fluidized beds - Experimental investigation and modelling
Financier Characterisation of signaling networks (in)activated by a new class of viral-encoded G-protein coupled receptors
Financier The chemistry of half-sandwich vanadium imido-amido complexes
Financier The catalytic mechanism of thermal chromophore isomerization in photoactive yellow protein
Financier Striated domains in biological model membranes AFM and computer simulation studies of lipid bilayers and the model peptide WALP
Financier Development of a helium-temperature high-resolution solid-state NMR probehead and its application in structural investigations of zeolites using novel homo- and hetero-nuclear correlation experiments for half-integer quadrupolar nuclei
Financier Assembly of synthetic and natural polymers; an artificial extracellular matrix
Financier Revealing the electronic structure of P680 by photo-CIDNP solid-state NMR
Financier Frozen-Density Embedding
Financier A combinatorial approach towards pharmaceutically relevant cyclic peptides
Financier High-valent silicon and low-valent phosphorus compounds
Financier Functional materials based on self-assembly of comb-shaped supramolecules
Financier 'Dialyzable' carbosilane dendrimers as soluble supports in the parallel synthesis of N-heterocycli
Financier Toposomes
Financier Development and application of 17O solid-state nuclear magnetic resonance methods for the study of hydrogen bond formations in biological and biomimicking materials
Financier NMR Studies of the Allosteric Effectors of the Lac Operon
Financier Microwave assisted multi-component reactions for parallel synthesis of libraries of N-heterocycles
Financier The application of multivariate probabilistic methods to X-ray crystallographic phasing and model refinement
Financier Development of combinatorial high pressure synthesis methods
Financier Light-driven molecular motors and switches. Controlling rotary motion and supramolecular helicity
Financier Structural studies of the sin3 co-repressor complex
Financier Epac: a novel cAMP
Financier Amphiphilic biohybrids
Financier Molecular motors under load
Financier Proteins in Action. Simulations of conformational changes in small proteins
Financier Supramolecular electronics
Financier Organic Chemistry in Living Cells: Profiling of Functional Biomolecules
Financier Structure and reactivity - theory-based design
Financier Fragment-oriented design of catalysts
Financier Magneto-optical molecular switches; turning paramagnetism on and off with light
Financier Analysis of cis- and trans-acting factors in TSWV transcription
Financier Fluorous Palladium Complexes for Carbonylation Reactions of Alkenes and Alkynes
Financier Steroids out of Carvon.
Financier The role of the bacterial SRP in targeting of protein precursors to the precursor protein translocon and insertion into or transport across the cytoplasmic membrane
Financier Genetic modification of plants by Agrobacterium tumefaciens
Financier Structure and dynamics of excited states of molecules
Financier Physics of optically excited states in solids

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