Organisation

Department of Internal Medicine

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Completed research

(the most recent research is at the top)
Collaboration	Neuromodulation of innate immune responses
Collaboration	Immune modulation and tolerance induction, prevention and inhibition of inflammatory diseases
Collaboration	Transition of systemic inflammation into multiorgan pathology
Collaboration	Applied Genomic Strategies for Treatment and Prevention of Cardiovascular Death in Uraemia and Endstage Renal Disease (GENECURE)
Secretariat	New molecular imaging in oncology: a focus on angiognesis
Secretariat	Applied Genomic Strategies for Treatment and Prevention of Cardiovascular Death in Uraemia and Endstage Renal Disease (GENECURE)
Secretariat	Aberrant signal transduction and protein expression in acute myeloid leukemia
Secretariat	Diagnostic, prognostic and therapeutic value of IGF-1 and IGFBP-3 in breast cancer.
Secretariat	Antisense proteinase 3 (PR3):a link between Staphylococcus aureus and PR3-ANCA associated vasculitis?
Secretariat	A search for missing pieces of the puzzle; the development of asthma and atopy. Innate immunity genes and environment
Secretariat	Anti-CD 20 treatment of relapsed or refractory immune thrombocytopenic purpura (ITP) after first line corticosteriod treatment
Secretariat	High dose Simvastatin combined with palliative chemotherapy (Hydrea or 6-Mercaptopurine) in patients with (relapse) acute myeloid leukemia not eligible for high dose chemotherapy. A phase II study.
Secretariat	High dose Simvastatin combined with standard chemotherapy (Daunorubicin and Cytarabin) in patients with relapse acute myeloid leukemia younger than 65 years. A phase II study.
Secretariat	Poor-risk aggressive lymphoma
Secretariat	Predictors and surrogate markers for control of asthma
Secretariat	An autofluorescence reader for advanced glycation end products (AGE's) in diabetes mellitus
Secretariat	Maintenance treatment of ANCA-associated vasculitis based on persistence of ANCA: a tailored approach
Secretariat	Gene therapy with VEGF (vascular endothelial growth factor) in patients with sclerodermia and ischaemic ulcers. A phase-II study
Secretariat	Mechanisms involved in the transition from primitive to definitive hematopoiesis and hematopoietic stem cell self-renewal
Secretariat	RhTRAIL to optimize chemotherapeutic efficacy in human ovarian cancer
Secretariat	Molecular testing for germline mutations in DNA mismatch repair genes: towards improved criteria for patient selection and variant interpretation
Secretariat	Characterization of signaling defects in granulocytes and myeloid precursor cells from myelodysplasia patients: its relation to apoptosis
Secretariat	The role of TRAIL mediated apoptosis in the development of colon carcinoma and possibilities for treatment and (chemo)prevention
Secretariat	Does an altered expression of multidrug-resistance proteins during viral and bacterial infections after liver transplantation attenuate the efficacy of immunosuppressive therapy?
Secretariat	Membrane expression of proteinase 3 on non-activated neutrophilic granulocytes: risk factor for ANCA-associated vasculitis
Secretariat	Diagnostic and pathogenetic significance of autoantibodies in autoimmune liver diseases
Secretariat	Role and regulation of constitutive NF-kappaB activity in acute myeloid leukemia (AML); its role in spontaneous apoptosis and clinical outcome.
Secretariat	Use of Fas-mediated apoptosis in human ovarian carcinoma to increase cisplatin sensitivity.
Secretariat	Non-invasive monitoring of modulating brain penetration of multidrug resistance involved chemotherapeutic drugs in vivo with radiolabeled verapamil and positron emission tomography (PET) in small cell lung cancer patients.