Organisation

Department of Internal Medicine

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Completed research

(the most recent research is at the top)
Collaboration	Genetic epidemiology of multiplex MS families
Secretariat	Specific homing of stem cells as a first step in environment guided differentiation of stem cells: towards increased efficacy and safety of stem celltherapy enhancing tissue (re)generation and neo....
Secretariat	The role of dendritic cel subsets in arthritis: an in vivo study
Secretariat	Novel roles of hemostatic proteins in human defence responses towards bacteria
Secretariat	Are post-splenectomy patients in the Netherlands managed according to international guidelines?
Secretariat	The NOXA/MCL-1 AXIS as therapeutic target in B-CLL
Secretariat	The role of CD44 splice-variants in reumatoïde arthritis
Secretariat	Clinical and molecular classification of very early rheumatoid arthritis
Secretariat	Drug surveillance in the IC-department
Secretariat	Towards operationally defined reference values for thyroid function tests
Secretariat	Incidence of errors in the intensive care: Effects of increased awareness and of improved communication by the introduction of explicit daily goals
Secretariat	Tick-host-pathogen interactions in Lyme borresliosis
Secretariat	Comparison of the effectiveness and tolerability of different doses of intravenous glucocorticoid for the treatment of moderately severe Graves
Secretariat	Endocrine resistance in breast cancer. Gene Expression Profiling and Modifications of the Estrogen Receptor
Secretariat	Treatment of type 3 Gaucher disease with enzyme supplementation and substrate reduction therapy.
Secretariat	The influence of hyperinsulinaemia and hyperglycaemia on the congenital immune response in bacterial infection
Secretariat	Blood coagulation disorders in diabetes mellitus
Secretariat	The basis of 'metabolism programming' in relation with perinatal feeding and its influence on the type 2 diabetes susceptability in adulthood
Secretariat	Role of cholinergic nervous system in collagen-induced arthritis in mice
Secretariat	Transmission of antiviral therapy resistent hiv-1 and hiv-1-subtypes in recently infected therapy-naive persons in the Netherlands
Secretariat	Surveillance of HIV-1 drug resistance in HAART treated patients and in the general population
Secretariat	Implementation research: operational aspects of diagnosis and treatment of HIV infection and tuberculosis at the district level
Secretariat	Building and implementation of high quality data systems
Secretariat	Building sustainable clinical trial capacity
Secretariat	Molecular basis of CD8+ T cell subset differentiation
Secretariat	Administration of hemodiluters with pneumonia
Secretariat	Neglected by death: mechanisms of dysregulated apoptosis in B-CLL
Secretariat	Subcutaneous insulin infusion in type 1 diabetes mellitus
Secretariat	Ethical aspects of palliative cancer chemotherapy
Secretariat	Cognitive Rehabilitation in Brain Tumor Patients
Secretariat	CD70 immuno-gene therapy for chronic lymphocytic leukaemia
Secretariat	Functional properties of chemokines and chemokine receptors in inflammatory joint disease
Secretariat	Ras family GTPase regulation of fibroblast-like synoviocytes in rheumatoid arthritis
Secretariat	Comparative efficiency of AAV serotypes for gene transfer in arthritis
Secretariat	Feasibility of gene therapy in arthritis models using an artificial chromosome expression system
Secretariat	Developing salivary gland gene therapy for the local signs and symptoms of Sjögrens syndrome
Secretariat	Consequences of CD97-CD55 interactions in arthritis
Secretariat	A double-blind study evaluating the effects of a C5a antagonist in comparison to placebo in patients with active rheumatoid arthritis
Secretariat	A double-blind, randomized, parallel group, placebo controlled, sequential dose escalation study of anti-MCP-1 therapy in patients with rheumatoid arthritis
Secretariat	A study to explore the changes in synovial inflammation and cytokine expression in patients with rheumatoid arthritis after treatment with prednisolone
Secretariat	Cost-effectiveness clinical study on infliximab treatment in rheumatoid arthritis
Secretariat	Mechanistic study on the effects of infliximab therapy in rheumatoid arthritis
Secretariat	Mechanistic study on the effects of infliximab therapy in psoriatic arthritis
Secretariat	Effect of IKK-2 dominant negative mutant gene transfer in adjuvant arthritis in rats with adeno associated viral vectors
Secretariat	Phenotypical and functional characterization of the CD4pos and CD8pos allorepertoire