| (the most recent research is at the top) |
| Collaboration |
Costs and effects of laparoscopy versus laparotomy in women with early endometrial cancer |
| Collaboration |
Physical fitness and training in chronic childhood conditions |
| Collaboration |
Results of triple arthrodesis and influence of alignment on the development of ankle arthrosis |
| Collaboration |
The development of a prognostic instrument for postoperative care for patients with a lumbar radicular syndrome in primary health care |
| Collaboration |
Oropharyngeal decontamination with chlorohexidine and chlorohexidine/colistine for the prevention of ventilator-associated pneumonia in ventilated intensive care patients |
| Collaboration |
Whiplash and its treatment |
| Secretariat |
An open multicenter randomized phase III study to compare oral Topotecan/Cisplatin versus Etoposide/Cisplatin as treatment for chemotherapy naive patients with small cell lung carcinoma in an advanced stage |
| Secretariat |
A four-week randomized, double-blind, parallel group, placebo controlled dose-response study evaluating the efficacy and safety of JTT-705 (300 mg or 600 mg) versus placebo in combination with pravastatin 40 mg in patients with type II hyperlipidemia |
| Secretariat |
A randomized double-blind study to evaluate the safety and efficacy of Etoricoxib 60 mg and Diclophenac sodium 150 mg in patients with osteoarthritis of the knee or hip. Protocol number MK-663-805-00 |
| Secretariat |
Portec 2 |
| Secretariat |
Study into the long-term effect of acetazolamide on ventilation, hypoxia and hypercapnia in hypercapnic COPD patients. Protocol number: February 2002 |
| Secretariat |
FACET study |
| Secretariat |
Efficacy and safety study of oral administration of SR48968C, NK2 antagonist, in patients suffering from irritable bowel syndrome (IBS). A multicentric, double-blind, placebo-controlled dose-ranging (phase IIB) study |
| Secretariat |
Christopher study |
| Secretariat |
EORTC 30987: randomized phase III study comparing paclitaxel/cisplatin/gemcitabine and cisplatin/gemcitabine in patients with metastatic or locally advanced urothelial cancer without prior systemic therapy |
| Secretariat |
Effects of ammonium chloride on ventilation, hypoxia and hypercapnia in hypercapnic patients with chronic obstructive pulmonary disease (COPD) |
| Secretariat |
The development of a prognostic instrument for postoperative care of patients who have been operated for a lumbosacral radicular syndrome |
| Secretariat |
Lamanoma study: conservative local treatment versus mastectomy after induction chemotherapy in locally advanced breast cancer: a randomized phase III study (EORTC) |
| Secretariat |
Clinical pharmacokinetics of oxaliplatin (Pt) in urine, blood and saliva |
| Secretariat |
An open label study of recombinant human activated protein C in severe sepsis. A phase IIIb clinical trial |
| Secretariat |
A phase III trial of LY900003 plus Gemcitabine and Cisplatin versus Gemcitabine and Cisplatin in patients with advanced, previously untreated non-small cell lung cancer. Protocol H7X-MC-JVAA |
| Secretariat |
COXARTROSE 189; target study |
| Secretariat |
Cost efficacy of an early switch from intravenous to oral antibiotic therapy versus 'normal care' intravenous antibiotic therapy in patients who are admitted with a serious pneumonia |
| Secretariat |
The hepatitis C - HIV Peg-interferon study |
| Secretariat |
Switch of antiretroviral therapy based on HIV resistance genotyping after failing protease containing regimens |
| Secretariat |
Performance of Lopinavir/Ritonavir as an Alternative Treatment Option (PLATO) |
| Secretariat |
EORTC 22996: a phase III double-blind, randomized, placebo-controlled study of erythropoietin when used as an adjuvant to radiation therapy in patients with head and neck squamous cell carcinoma |
| Secretariat |
Efficacy and safety study of Alitretinoin (BAL 479) in the treatment of chronic hand dermatitis. Protocol number BAP 00003B |
| Secretariat |
A double blind, placebo controlled, parallel group study of the effects of Zoniporide on perioperative cardiac events in high risk subjects undergoing noncardiac vascular surgery (#A3181007) |
| Secretariat |
Memory disorders in patients undergoing a heart catheterisation. Protocol version 14 October 2001 |
| Secretariat |
Extracorporeal radial shock wave therapy of chronic rotator cuff tendinitis shoulders |
| Secretariat |
A randomized phase III study into the effect of thalidomide in combination with adriamycin, dexamethsone (AD) and high dose melphalan in patients with multiple myeloma (HOVON-50 MM) |
| Secretariat |
MOSAIC studie |
| Secretariat |
Three-dimensional conformal radiotherapy alone vs three-dimensional conformal therapy plus adjuvant hormonal therapy in localized T1b-c, T2a, NO, MO prostatic carcinoma. A phase III randomised study |
| Secretariat |
SKATE: safety of Keppra as supplementary therapy of epilepsy |
| Secretariat |
ONTARGET (ongoing telmisartan alone and in combination with ramipril global endpoint trial) |
| Secretariat |
A phase IV, multicenter, comparative study in preterm children who previously received Synagis prophylaxis versus preterm children without RSV prophylaxis: development of reactive airway disease |
| Secretariat |
Prevention of multiple birth pregnancies after in vitro fertilisation: a prospective randomized study |
| Secretariat |
A phase III extension study to evaluate the safety of 10 mg Atrasentan in men with hormone-refractory prostate cancer. MOO-258 (version date 16 April 2001) |
| Secretariat |
A phase II, randomized, double-blind, placebo-controlled study into the safety and efficacy of 10 mg Atrasentan in men with non-metastatic, hormone-refractory prostate cancer. MOO-244 (version date 9 May 2001) |
| Secretariat |
A phase III, randomized, double-blind, placebo-controlled study into the safety and efficacy of 10 mg Atrasentan in men with metastatic, hormone-refractory prostate cancer. M00-211 (version date 19 April 2001) |
| Secretariat |
European trial into atrial fibrillation or flutter patients receiving Dronedarone for the maintenance of sinus rhythm (EURIDIS). Protocol EFC3153 d.d. 03/07/01. IB SR33589B d.d. 13/06/01, edition E05 |
| Secretariat |
Safety and efficacy of abacavir vs combination therapy in antiretroviral naive HIV-1 infected subjects |
| Secretariat |
A phase II study of docetaxel in combination with gemcitabine in patients wit metastatic breast cancer |
| Secretariat |
Three-arm randomized parallel phase II/III study evaluating the efficacy of the combinations of epirubicin and taxotere (ET), taxotere and navelbine (TN) and epirubicin and navelbine (EN) as first-line therapy in patients with metastatic breast cancer |
| Secretariat |
EORTC protocol 22996. A phase III double-blind, randomised placebo-controlled study of erythropoietin when used as an adjuvant to radiotherapy in patients with head and neck squamous cell carcinoma |
| Secretariat |
SAGE trial |
| Secretariat |
Extrapolating costs and effects of randomised clinical trials to daily practice cost-effectiveness in cancer research. Costs of NHL treatment. Observational study. Protocol for the Netherlands |
| Secretariat |
Celikeys clinical evaluation of Celikey TM in celiac disease |
| Secretariat |
A randomized, double-blind, placebo-controlled, multicenter phase II study of CI-994 in combination with paclitaxel and carboplatin infusions versus placebo in combination with paclitaxel and carboplatin infusions in the first-line treatment of patients with advanced non-small cell lung cancer |
| Secretariat |
Medicamentous treatment against the recurrence of neoplastic poplyps in the colon in patients with a history of colorectal carcinoma |
| Secretariat |
Second trimester abortions with congenital abnormalities or IUVD |
| Secretariat |
EORTC Amaros trial 10981: After mapping of the axilla: radiotherapy or surgery? |
| Secretariat |
Efficacy and safety of different doses of BIRB 796 BS in patients with active reumatoid arthritis |
| Secretariat |
Progastro study |
| Secretariat |
Efficacy and safety of Pregabalin using an individual optimal twice a day (BID) dose schedule in patients with chronic neuropathic pain. Protocol nr. 1008-155 and 1008-166. IB 21/2/01 |
| Secretariat |
Effectiveness of small doses of sedatives on the success of non-invasive respiration of patients suffering from acute respiratory insufficiency |
| Secretariat |
Risk stratification of patients admitted to a hospital with an acute coronary syndrome (the ICTUS cohort study. Version 1. June 13, 2000) |
| Secretariat |
Invasive versus conservative treatment in unstable coronary syndromes (the ICTUS trial). Version 1. September 14, 2000 |
| Secretariat |
6-Thioguanine orally for inflammatory bowel disease in patients who had negative experiences with azathioprine or 6-mercaptopurine. Version 98.1 |
| Secretariat |
Open-label long-term study in patients with chronic heart failure who have completed the controlled clinical study ENABLE 1 (AC-052-301) or ENABLE 2 (AC-052-302),. Protocol no. AC-052-303 |
| Secretariat |
Double-blind, placebo-controlled, randomised, withdrawel trial assessing the efficacy and tolerability of 'on-demand' maintenance therapy with rabeprazole |
| Secretariat |
An open label, long-term safety and efficacy follow-up study of YM 905 5 mg and 10 mg in patients with overactive bladder. Study no. 905-CL-019, Final protocol 22 February 2001 |
| Secretariat |
Efficacy of fibres and oligosaccharides in the treatment of constipation in children (project no. 9001, November 20, 2000) |
| Secretariat |
The effect of nutritional supplements on remission maintenance in patients with Crohn's disease |
| Secretariat |
Evaluating the benefit of continuous versus on demand Nexium therapy: a randomised study on the efficacy of maintenance therapy in gastroesophageal reflux disease (BRILLIANT) |
| Secretariat |
A randomised, double-blind, study comparing Arimidex TM with Nolvadex TM as neo-adjuvant and adjuvant treatment in postmenopausal women with large operable (T2 [.3 cm], T3, NO, MO) or potentially operable, locally advanced (T4, NO-2, MO) ER+ and/or PR+ breast cancer |
| Secretariat |
A multicentre, double-blind, randomised, placebo and Tamsulosin 0,4 mg controlled parallel group study to assess the efficacy and safety of UK-338,003 in patients with lower urinary tract symptoms due to malignant prostatic obstruction. Study no. A284-1010, final protocol 22 January 2001 |
| Secretariat |
Magnetic resonance spectrocopy of the foetal brains |
| Secretariat |
A pharmacokinetic study to determine the dose regimen for the combination indinavir/ritonavir and rifampicine for people who are suffering from tuberculosis and who are HIV-positive |
| Secretariat |
Randomized phase III step-up study undisturbed. Initial anti-androgen monotherapy in comparison with watchful waiting in asymptomatic T1-3 any G [any Gleason] NO of Nx MO prostate cancer patients without local treatment with curative intention. EORTC-protocol 30991, 9 November 2000 |
| Secretariat |
An open non-randomized survey into the efficacy and tolerability of rabeprazol [brand name Pariet] in daily practice in a large patient population being treated for reflux disease [GORD: gastro oesophageal reflux disease]. RAB-NED-1. Protocol 21/02/00 |
| Secretariat |
A trial to evaluate the long-term tolerability and safety of R149514 compared with placebo in diabetic subjects with symptoms of gastroparesis. Protocol 20 November 2000 |
| Secretariat |
A randomised, double-blind, parallel group, placebo and active multi-centre study of YM905 5 mg and 10 mg in patients with overactive bladder. Study no. 905-CL-015, final protocol 23 November 2000 |
| Secretariat |
EORTC protocol 62991-22998. Phase II pilot study into moderate doses of radiotherapy for inoperable aggressive fibromatosis |
| Secretariat |
Recurrent otitis media with effusion in children |
| Secretariat |
Protocol H4Z-MC-JWXD: Phase 3 randomized double-blind evaluation of LY353381 compared with tamoxifen in women with locally advanced or metastatic breast cancer |
| Secretariat |
Phase III double-blind efficacy and safety study of SCH 58235 [10 mg]. |
| Secretariat |
Integrity AfX-DAO study [septal wall] study |
| Secretariat |
MATCH-study |
| Secretariat |
Long-term effects of salmeterol and fluticason propionate, in combination and alone, on the survival of patients with chronic obstructive pulmonary disease |
| Secretariat |
OVERTURE: omapratilat versus enapralil randomized trial of utility in reducing events |
| Secretariat |
Prevention of peri-articular ossifications with primary total hip prostheses by 7 days rofecoxib and 7 days indomethacin postoperative: a prospective, randomised, double-blind study |
| Secretariat |
The effect of BCG-vaccination on the course and the development of asthma in children |
| Secretariat |
Immediate vs later intravesical mitomycin C administration for mild papillary transitional cell carcinoma of the bladder. A multicenter open-label randomized phase III study. Protocol DNE-13 |
| Secretariat |
Feasibility study of the combination of radiotherapy, chemotherapy and hyperthermia for the treatment of stage IIB-III-IVA cervical cancer. Protocol 19 January 2000 |
| Secretariat |
SENIORS study: research into the effects of Nebivolol intervention undisturbed |
| Secretariat |
R149524-INT-2 - A double-blind, placebo controlled close-finding trial to evaluate the efficacy and safety of Rechter 149524 in diabetic patients with symptoms of gastroparesis |
| Secretariat |
Protocol MK-0966: phase III extension study |
| Secretariat |
A double-blind study evaluating the efficacy and safety of the combination of etanercept and methotrexate in comparison to atanercept alone or methotrexate alone in rheumatoid arthritis patients. Protocol 0881A1-308-EU |
| Secretariat |
The effect of a specific supplement on symptom relief in patients with arthritis |
| Secretariat |
Phase III randomized study of adjuvant immunotherapy with monoclonal antibody 17-1a versus no adjuvant therapy following resection for stage II [modified Astler-Coller B2] adenocarcinoma of the colon |
| Secretariat |
Unguius incarnatus |
| Secretariat |
Double blind, placebo controlled dose-repsonse study into insulin suppressive effects in obese adult males |
| Secretariat |
Neonatal morbidity after vacuum or forceps deliveries |
| Secretariat |
Allergic cross reaction pattern of conventional and new generation inhalers |
| Secretariat |
An efficient diagnostic strategy in fecal incontinence |
| Secretariat |
A study evaluating the inititiation of fixed doses of novel erythropoiesis stimulating protein (NESP) therapy in subjects with end-stage renal disease |
| Secretariat |
Open multicentre study to evaluate the percentage of hemodialysis patients maintaining constant hemoglobin values when switching from 2x or 3x weekly intravenous or subcutaneous application to once weekly application of epoietin alpha |
| Secretariat |
An open label, multicentre, randomised, phase III comparative study of active symptom control, alone or in combination with oral Topotecan, in patients with recurrent resistant SCLC.b |
| Secretariat |
A randomized, double blind, phase III comparative trial of 2 doses of ZD 1839 (IRESSA TM) in combination with gemcitabine and cisplatin versus placebo in combination with gemcitabine and cisplatin in chemotherapy naive patiens with advanced (stage III of IV) non-small cell lung cancer |
| Secretariat |
Patient acceptability study of mesalazine (Pentasa) prolonged release microgranules dosed as either tablets or sachets in patients with ulcerative colitis. Trial code Penta 99/01/NL |
| Secretariat |
Taxotere and cisplatin as induction chemotherapy in patients with stage IIIa NSCLC |
| Secretariat |
A randomized trial into feedback on electronically measured medication dosing to improve adherence to antiretroviral drugs in HIV-infected individuals |
| Secretariat |
A multicenter, randomized, open-label, comparison study into the safety and efficacy of intravenous GAR-936 and intravenous Ciprofloxacin in the treatment of complicated urinary tract infections in hospalized patients |
| Secretariat |
A randomised, double-blind, parallel-group pilot trial to examine the efficacy, safety and tolerability of two doses of ZD1059 (50 mg and 100 mg po daily) and CASODEX TM 150 mg monotherapy in prostate cancer patients |
| Secretariat |
Tolerance and efficacy of iron supplemented baby food in former prematures |
| Secretariat |
TACTICS-study, transfusion associated complications: transfusion induced complications? |
| Secretariat |
A double-blind, randomized, placebo-controlled, parallel group study assessing the efficacy and safety of oral fexofenadine HCI tablets 30 mg twice daily in pediatric subjects (6 to 11 years) in the treatment of seasonal allergic rhinitis |
| Secretariat |
Open label trial into the safety and efficacy of leflunomide in patients with rheumatoid arthritis |
| Secretariat |
Docetaxel and carboplatin once every 3 weeks versus weekly docetaxel in advanced non-small cell lung cancer: a multicenter phase III study under the auspices of the Dutch chest physicians association |
| Secretariat |
PROPAC study: postanoxic coma |
| Secretariat |
Lung embolism: LEVENTAS [Lung embolism And VEnous Thrombosis Arnhem Study] |
| Secretariat |
A double-blind, randomized, placebo-controlled study into the efficacy and safety of Eplerenone with patients suffering from heart failure after an acute myocardial infarction (IND # 51,7890). [Protocol IE3-99-02-035] |
| Secretariat |
BIAsp-107. A multinational, randomised, open-labelled, parallel group 4 months comparison of twice daily biphasic human Insulin 30 and thrice daily biphasic insulin Aspart in patients with type 1 or 2 diabetes |
| Secretariat |
PEG-interferon and Lamivudine combination therapy in patients with chronic HBV infection (HBV 99-01 study) |
| Secretariat |
Laparoscopic versus rupture of scar tissue surgery. Colibri trial. 172.470/1998/145 |
| Secretariat |
Ifegenia study, 7112 LA-MC 101. Idiopathic lung fibrosis (NAC) |
| Secretariat |
Pentua study |
| Secretariat |
Antibiotica versus antibiotica plus G-CS. CWOM 9712-0241 CDE plus C-CSF plus/min antibiotica |
| Secretariat |
PEG-interferon and Lamivudine combination therapy in patients with chronic HBV infection (HBS 99-01 study) |
| Secretariat |
Study on chronic hepatitis C treatment with Interferon Alpha, Ribavarin and Amantadine in naive patients [CIRA study] |
| Secretariat |
Valdecoxib 20mg/40 mg + diclophenac 75 mg SR 2 dd. in rheumatoid arthritis |
| Secretariat |
Valdecoxib 10/20 mg + diclophenac 75 mg SR 191-02-063 in rheumatoid arthritis |
| Secretariat |
ARES study: Antiretroviral Regimen Evaluation Study |
| Secretariat |
Pseudocroup study |
| Secretariat |
Benign prostate hyperplasia ARI 4002 |
| Secretariat |
Heptatits C - HIV study |
| Secretariat |
TRAC study: Celecoxib 200 mg |
| Secretariat |
Vac 2000: vacuum assisted closure versus wound healing with hydroactive bandage |
| Secretariat |
Erosive reflux study E 3810 - 403 |
| Secretariat |
Mamma care outcome by telephone |
| Secretariat |
CIPEP: clinical inhalation profiles in exacerbation and protection. Study 2 Inhalation profile: the course of an exacerbation |
| Secretariat |
Palliation with inoperable esophageal carcinoma stent versus brachytherapy |
