KNAW

Organisation

Oncology Graduate School Amsterdam

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Completed research

(the most recent research is at the top)
Collaboration Tumor metastasis: the role of acto-myosin contraction in the downregulation of E-cadherin-mediated cell-cell adhesion
Collaboration Pharmacokinetics of monoclonal antibodies
Collaboration Generation and validation of cytochrome P450 3A knockout and transgenic mice as tools for improved drug development and research
Collaboration FDG-PET for avoidance of futile direct laryngoscopies under general anaesthesia with taking of biopsies in patients with suspicion on recurrent laryngeal carcinoma after radiotherapy
Collaboration FANCM, the mouse that roared
Collaboration Whole genome analysis of the regulation of chromatin structure and gene expression
Collaboration L1 and Alu elements: structural and functional analysis of human non-LTR retrotransposons
Collaboration Mutational and functional analysis of the EGFR pathway in NSCLC patients: correlation with prognosis and response to small-molecule EGFR inhibitors
Collaboration TSLC1 silencing: a marker for risk assessment of cervical cancer
Collaboration Subtle gene modification to study the role of the mismatch repair complex MSH2/MSH6 in mutation avoidance and tumor suppression
Collaboration Function of integrin-CD151 complexes in tumor cell invasion and metastasis
Collaboration Long-term psychosocial impact of genetic testing among familial adenomatous polyposis (fap) families
Collaboration Chemistry-based functional proteomics: new tools for immunology and cell biology
Collaboration Predicting lymph node status in gastric cancer by dna-based genomic profiling for stratifying surgical therapy
Collaboration Molecular bar code screens to identify genetic interactions with protein kinases in mammalian cells
Collaboration Tiam1/Rac signaling and Wnt/[beta]-catenin-induced tumorigenicity
Collaboration Structural analysis of the mechanism of ubiquitin conjugation, a generalized cellular addressing system, that controls protein and DNA stability
Collaboration Experimental and clinical studies using positron emission tomography (PET) for monitoring response to chemotherapy in (locally) advanced breast cancer
Secretariat Modulation of Fenecitinide induced apoptosis in Neuroblastoma cells
Secretariat Human brain tumour studies: Radiosensitization & Genetics
Secretariat Targeted therapy in pediatric brain tumors
Secretariat Innovative therapy for childhood brain tumors
Secretariat Positron Emission Tomography (PET) in the diagnosis of head and neck squamous cell carcinoma (HNSCC)
Secretariat Hypothyroidism after treatment for laryngeal cancer
Secretariat Psychosocial functioning and quality of life of retinoblastoma survivors and parents in the Netherlands
Secretariat Circulating endothelial cells as markers for antiangiogenic therapy
Secretariat Folate supplementation in chemotherapy: increase of efficacy versus induction of drug resistance
Secretariat Clinical trials with receptor tyrosine kinase inhibitors in patients with advanced cancer
Secretariat In vitro activity and mechanism of action of multidrugs
Secretariat Dual role of thymidine phosphorylase inhibition; enhancement of cytotoxicity and angiogenesis
Secretariat Colorectal polyps and cancer in Amsterdam
Secretariat The impact of OATP drug carriers on in vivo pharmacology toxicology & physiology
Secretariat Preclinical and clinical pharmacology of oral drugs
Secretariat Impact of the multidrug transporters p-glycoprot., MRP2 and BCRP on the behaviour of anti-cancer drugs
Secretariat Molecular prediction of therapy outcome in breast cancer
Secretariat The role of FDG PET in eosphageal cancer staging and monitoring the response to neoadjuvant therapy
Secretariat Optimization of US selection criteria of lymph nodes (size, laterality, aspect and behaviour) to perform USgFNAC in follow-up of patients's oral cavity or oropharyngeal carcinoma
Secretariat CRC (colorectal cancer) screening by faeces DNA based testing using chromosome 20q genes
Secretariat Targeted therapies in head and neck cancer
Secretariat Evaluation of scanners for positron emission tomography in oncology
Secretariat Serum tumrour markers in cervical carcinoma
Secretariat Cellular barcoding and dissection of T cell differentiation
Secretariat The role of histone methylation in silencing and transcriptional memory
Secretariat Analysis of the function of a novel nuclear envelope protein, nesprin-3, in anchoring the nucleus to the intermediate filament system
Secretariat Development & application of shRNA (short hairpin RNA) in cell based screening technologies
Secretariat Prevention and therapy of tumors
Secretariat Diagnosis of tumors
Secretariat The role of APRIL and its receptors in tumor growth and immune regulation

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