| (the most recent research is at the top) |
| Collaboration |
Efficient development of small molecule inhibitorsof tyrosine kinases - Identification of EphA4 blockers as anti-cancer lead compounds |
| Collaboration |
Imagining Genomics: Introducing visuality in the genomics debate |
| Collaboration |
Fundamentals of a new class of oxidation processes based on thermal and photo-catalysis in basic zeolites (TPC.6057 |
| Collaboration |
Nickel N-heterocyclic carbene complexes in homogeneous catalysis |
| Collaboration |
B-Basic: Bio-based Sustainable Industrial Chemistry |
| Collaboration |
Structural enzyme kinetics: studies on Chlorella DNA ligase |
| Collaboration |
On the stability of molecules and microorganisms in planetary and interstellar environments |
| Collaboration |
Characterization of Thin Film Photoanodes for Solar Water Splitting |
| Collaboration |
Numerical algorithms in bio-informatics |
| Collaboration |
Design, synthesis and application of molecularly defined TLR ligand-antigen conjugates for optimal DC activation and specific T cell induction. |
| Collaboration |
ECOX Project - Oxidation catalysis for sustainability inside the chemical and detergent industry |
| Collaboration |
Molecular order in and around "lipid rafts" |
| Collaboration |
Organic chemistry on Mars |
| Collaboration |
Development of a novel class of catalysts using the combinatorial chemistry approach |
| Secretariat |
Interfacing Functional Nanocomposites for Non-Volatile Memory Devices |
| Secretariat |
Development of advanced drug discovery methods |
| Secretariat |
Imaging of dynamic events with cryo-EM: digital, time-resolved quantum imaging of viruses and other macromolecular complexes |
| Secretariat |
GENomics and EXpression of Peptide ANtibiotics and Derivatives (GENEXPAND) |
| Secretariat |
Theoretical characterization and optimization of transition metal synthetic catalysts for water oxidation |
| Secretariat |
Structure-based insights into the repair of UV-damaged DNA |
| Secretariat |
Outsmarting Influenza and Chagas Disease: Developing Mechanism-based Sialidase Inhibitors for Study and Treatment |
| Secretariat |
Energy-Transfer Phenomena in Solution and at Surfaces |
| Secretariat |
Potential-dependent ab initio calculations of dissociative water adsorption on stepped platinum surfaces |
| Secretariat |
Novel mechanisms in bacterial cell division: an integrated approach to unravel the septum localising complex of streptomycetes |
| Secretariat |
Step Away From Flat Land; employing a Cylindrical Crystal in Gas-Surface Dynamics Studies |
| Secretariat |
In vivo µMRI and MRS studies in assessment of early biomarkers of AD |
| Secretariat |
Deployment of the Leiden Grid Infrastructure |
| Secretariat |
Developing a chloride-free route to epoxy resins |
| Secretariat |
Facility for on-line product detection in selective electrocatalysis |
| Secretariat |
Dimeric ligands for GPCRs involved in human reproduction: synthesis and biological evaluation |
| Secretariat |
Mechanisms of hydrogen storage in alanates; a first principles approach |
| Secretariat |
Programmed DNA directed molecular self-assembly of redox proteins in biosensor design |
| Secretariat |
New approaches for accurate and efficient macromolecular crystal structure solutions |
| Secretariat |
New directors in the cell division orchestra: coordinating multiple septation and chromosome segregation in filamentous streptomycetes |
| Secretariat |
Nucleotide Excision Repair in Yeast |
| Secretariat |
Damage recognition in nucleotide excision repair |
| Secretariat |
Peptide-polymer hybrid coatings with antibiotic activity |
| Secretariat |
A protein-based artificial solar antenna derived from biological self-organization principles |
| Secretariat |
Hydrogen storage in nanoporous clathrate materials |
| Secretariat |
The palladium diphosphane catalyzed reduction of nitrobenzene |
| Secretariat |
Parallellisation SURFSCAT |
| Secretariat |
Spin torch experiments observed in reaction centers of Rhodobacter sphaeroides |
| Secretariat |
Ab initio modeling of primary processes in photosynthesis: Protein induced activation of bacteriochlorophylls for efficient light harvesting and charge separation |
| Secretariat |
Photo-CIDNP MAS NMR on isotope-labeled photosynthetic reaction centers |
| Secretariat |
Chemical activity of anticancer compounds: computational studies on the mechanism of bleomycin and the recognition of flavonoids |
| Secretariat |
In vivo high field magnetic resonance imaging and spectroscopy of adult zebrafish |
| Secretariat |
Photo-CIDNP MAS NMR on oriented photosynthetic reaction centers |
| Secretariat |
Magnetic resonance imaging and spectroscopy of Alzheimer's disease in transgenic mice in vivo |
| Secretariat |
Biological photoreceptors |
| Secretariat |
Molecular Structure and Function of Proline Rich Proteins |
| Secretariat |
Magnetic Resonance Microimaging on the Zebrafish |
| Secretariat |
Magnetic Resonance Imaging (MRI) of Alzheimers Disease (AD) |
| Secretariat |
Electronic Structure of Coordinating Histidines in Photosynthetic Complexes |
| Secretariat |
Antioxidant properties of small proline-rich proteins |
| Secretariat |
Influence of the DDB1/2 complex on DNA damage signaling in murine keratinocytes |
| Secretariat |
Interplay between DNA damage responses in UV-exposed murine skin |
| Secretariat |
MelC1 of Streptomyces antibioticus, an accessory protein of tyrosinase involved in secretion and copper incorporation. |
| Secretariat |
The relation between copper homeostasis and morphological differentiation in Streptomyces |
| Secretariat |
In search for anticancer transition-metal compounds with dual DNA-binding and cleaving properties |
| Secretariat |
The design and synthesis of novel heterodinuclear complexes combining a DNA cleaving agent and a DNA targeting moiety |
| Secretariat |
Synthesis, Characterization and Biological Studies of Ruthenium and Gold Compounds with Anticancer Properties |
| Secretariat |
Ruthenium polypyridyl complexes with anticancer properties |
| Secretariat |
Phenol-pyrazole based ligands towards the design of manganese complexes |
| Secretariat |
New d-f multifunctional molecular materials |
| Secretariat |
Catalytic allylation of phenols: chloride-free route towards epoxy resins |
| Secretariat |
Homogeneous bio-inspired copper-catalyzed oxidation reactions |
| Secretariat |
Structural and functional models for [NiFe] hydrogenase |
| Secretariat |
Towards peptide based therapeutics-Applications in celiac disease and infectious diseases |
| Secretariat |
A search for a facile synthesis route towards immunological important sugar building blocks |
| Secretariat |
Protein nanocrystallisation |
| Secretariat |
Method development for Cryo-electron microscopy |
| Secretariat |
Profiling of Soluble and Membrane-Bound Metalloproteases: A Targeted Proteomics Approach |
| Secretariat |
Synthetic Methodology for the Preparation of Nucleic Acid Containing Peptides |
| Secretariat |
Manganese-enhanced MRI of migraine mice:in vivo evaluation of calcium channel functioning |
| Secretariat |
Novel Methods for Fragment-based Drug Discovery |
| Secretariat |
Hybrid quantum mechanics-molecular mechanics study of the bleomycin acitvity |
| Secretariat |
Cyttron: A window on the molecular machinery of life |
| Secretariat |
Dynamics and structural features of the microtubule plus-ends in interphase mouse fibroblasts |
| Secretariat |
Molecular approach |
| Secretariat |
From 3D structure to cell biology: new roles for replication factor C |
| Secretariat |
Whole cell catalysed conversion innovated by peptaibol mediated transport of polar compounds across the bacterial cell membrane |
| Secretariat |
Search for regulatory elements of the streptomycin operon of E. coli by means of DNA/RNA combinatorial chemistry methods |
| Secretariat |
Nanosized Au clusters as novel catalysts for low-temperature CO oxidation and selective oxidation of light hydrocarbons |
| Secretariat |
Experimental and theoretical studies of non-linear phenomena in catalytic oxidation of NH3 and reduction of N2O over platinum metal surfaces: intermediates, phase transitions, oscillations, mathematical modelling |
| Secretariat |
Bifunctional metal complex binding to DNA: medicinal aspects |
| Secretariat |
Self-replicating polymersomes |
| Secretariat |
Translational control by a molecular Trojan horse |
| Secretariat |
RNA pseudo-triloops: key structures in RNA-protein recognition and targets for potential drugs |
| Secretariat |
Quantum dynamics of chemical reactions |
| Secretariat |
Structural and biochemical characterization of the BRTC domains and their ligand interactions of the human breast cancer susceptibility gene 1 (BRCA1) protein |
| Secretariat |
Coordination chemistry of manganese and iron with N,O-donor ligands: oxidation catalysis and magnetochemistry of clusters |
| Secretariat |
Ultrafast studies of chemical reactions at surfaces |
| Secretariat |
Native chemical glycosylation - A novel and efficient method for the synthesis of complex glycoconjugates |
| Secretariat |
Reconstruction of the ribosome |
| Secretariat |
Computational chemistry for biological systems |
| Secretariat |
Crank-automated crystallographic structure solution |
| Secretariat |
Oxacarbenium ion intermediates in the stereoselective synthesis of anionic oligosaccharides |
| Secretariat |
Single-enzyme electrochemistry at nanoelectrodes |
| Secretariat |
The solid-state photo-cidnp effect |
| Secretariat |
Pushing the mesoscopic frontier |
| Secretariat |
Parallelization and optimization of wave packet code for moleculesurface scattering for use on Teras, Aster, Solo and Lisa |
| Secretariat |
Bridging the gap between natural & artificial light-harvesting |
| Secretariat |
Electronic and spatial characteristics of the retinylidene chromophore of rhodopsin |
| Secretariat |
Multiplex sum-frequence generation (SFG) microspectroscopy |
| Secretariat |
Structural biology of induced conformational changes |
| Secretariat |
Electron transfer correlated protein dynamics |
| Secretariat |
Photo-CIDNP solid-state MR on oriented photosynthetic membranes revealing the spatial and electronic structure of the primary electron donors |
| Secretariat |
Catalytic behaviour of Cu, Ag and Au nanoparticles |
| Secretariat |
Production and storage of hydrogen; a first principles approach |
| Secretariat |
Transient interactions between photosynthetic proteins |
| Secretariat |
EPR and NMR Spectroscopy on Spin Labeled Proteins |
| Secretariat |
Synthesis studies of the zwitterionic polysaccharide PS A1, a major cause of human abdominal abscesses |
| Secretariat |
Transient complexes of haem proteins |
| Secretariat |
Revealing the electronic structure of P680 by photo-CIDNP solid-state NMR |
| Secretariat |
The application of multivariate probabilistic methods to X-ray crystallographic phasing and model refinement |
| Secretariat |
Organic Chemistry in Living Cells: Profiling of Functional Biomolecules |
| Secretariat |
Three-dimensional molecules |
| Secretariat |
Control of microbial morphology: novel regulators of cell division |
| Secretariat |
Femtosecond dynamics of surface chemistry |
| Secretariat |
Crystallographic structure determination of receptor-ligand complexes involved in adenovirus infection and T-cell stimulation |
