Prof.dr. J.A. Grootegoed

Update Persondata

• biochemical
• cell
• chromosome
• endocrinology
• expression
• gene
• genes
• mice
• receptor
• repair
• transcription

Active as

Publications

(the most recent at the top)

Human RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double strand breaks

RNF12 activates Xist and is essential for X chromosome inactivation

RNF12 activates Xist and is essential for X chromosome inactivation

The ubiquitin-conjugating enzyme HR6B is required for maintenance of X chromosome silencing in mouse spermatocytes and spermatids

The probability to initiate X chromosome inactivation is determined by the X to autosomal ratio and X chromosome specific allelic properties

All publications..

Current research

(the most recent research is at the top)
Project leader	Hedgehog signaling in mammalian gonadal development and function

Completed research projects

(the most recent research is at the top)
Project leader	Gametogenesis and infertility
Project leader	Reproduction and development

Classification

D21700	Physiology