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Person

Prof.dr. R.A. Bernards

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Update Persondata

Expertise	Cell cycle; Cancer; Oncogenes; Tumorsuppressor; Genes RNA interference
Expertise (NL)	Celcylus; Kanker; Oncogenen; Tumorsuppressor; Genen RNA interferentie
Digital Author ID	info:eu-repo/dai/nl/304813656
KNAW member	Science Division
Addition	Head, division of molecular carcinogenesis, Netherlands Cancer Institute, Amsterdam
Grants/prizes	NWO - Spinozapremie 2005

Active as

Programm leader / Group leader
Organisation	The Netherlands Cancer Institute
Chair (EN)	Molecular carcinogenesis
Chair (NL)	Moleculaire carcinogenese
Phone	+31-20-5121952
Email	r. bernards -at- nki. nl
URL	http://www.biomedicalgenetics.nl/participant.php?participant...

Part-time professor
Organisation	Department of Molecular Cancer Research (UU)
Chair (EN)	Molecular carcinogenesis
Chair (NL)	Moleculaire Carcinogenese
Email	r. bernards -at- nki. nl

Current research

(the most recent research is at the top)
Project leader	Identification of enzymes involved in regulatory ubiquitination in TNF a--stimulated signalling by loss-of-function screens
Project leader	Understanding resistance to HER2-targeting therapy in human breast cancer through functional genetics
Project leader	Development & application of shRNA (short hairpin RNA) in cell based screening technologies
Project leader	Biosynthesis and function of base J, a new base in the nuclear DNA of kinetoplastid parasites
Researcher	Cancer proteomics

All current research..

Completed research projects

(the most recent research is at the top)
Project leader	A study of drug resistance mechanisms using large-scale RNA interference screens
Project leader	The role of PRAME in oncogenesis
Project leader	High throughput functional genetic screens for stable loss-of-function phenotypes in mammalian cells
Project leader	Isolation and functional analysis of novel genes that act in the p16INK4A-cyclin D-pRB-E2F pathway
Project leader	A functional genomics approach to identify genes which influence tumor cell behavior in vivo

All completed research..

Classification

D21400	Genetics
D23120	Oncology

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