Prof.dr. J.H. Beijnen

Update Persondata

• analytic
• breast
• cancer
• drugs
• mice
• patients
• protein
• risk
• serum
• toxic
• toxicology
• treatment
• tumor

Active as

Publications

(the most recent at the top)

Early diagnostic protein biomarkers for breast cancer: how far have we come?

Search for Breast Cancer Biomarkers in Fractionated Serum Samples by Protein Profiling With SELDI-TOF MS

Lipopolysaccharide contamination in intradermal DNA vaccination : toxic impurity or adjuvant?

Specific Investigation of Sample Handling Effects on Protease Activities and Absolute Serum Concentrations of Various Putative Peptidome Cancer Biomarkers

Shielding the cationic charge of nanoparticle-formulated dermal DNA vaccines is essential for antigen expression and immunogenicity

All publications..

Current research

(the most recent research is at the top)
Project leader	Clinical Pharmacology
Project leader	Biomedical Analysis : Functional and structural characterization
Project leader	Slotervaart HIV cohort study - Part II: Pharmacokinetics and -genetics of highly active antiretroviral therapy (HAART) in HIV infection

Completed research projects

(the most recent research is at the top)
Researcher	Generation and validation of cytochrome P450 3A knockout and transgenic mice as tools for improveddrug development and research.
Project leader	Prediction of pharmacokinetic interactions between complementary, alternative medicines and (new) anticancer drugs
Project leader	OATP1A/1B (SLCO1A/1B) drug uptake transporters in anticancer drug pharmacokinetics and toxicity risks; possible strategies for therapy optimization
Project leader	The impact of OATP drug carriers on in vivo pharmacology toxicology & physiology
Project leader	Preclinical and clinical pharmacology of oral drugs

All completed research..

Classification

A34800	Drugs and pesticides
D23340	Biopharmacology, toxicology