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Prof.dr. J.H. Beijnen

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Expertise Analytic drugs toxicology
Expertise (NL) Analytische geneesmiddelentoxicologie
Digital Author ID info:eu-repo/dai/nl/071919570
KNAW member Science Division

Active as

Professor
Organisation Department of Pharmaco-epidemiology and Clinical Pharmacology (UU)
Chair (EN) Analytic drugs toxicology
Chair (NL) Analytische geneesmiddelentoxicologie
Phone +31-30-2537324
Email jos. beijnen -at- slz. nl

Publications

Lipopolysaccharide contamination in intradermal DNA vaccination : toxic impurity or adjuvant?
Shielding the cationic charge of nanoparticle-formulated dermal DNA vaccines is essential for antigen expression and immunogenicity
Specific Investigation of Sample Handling Effects on Protease Activities and Absolute Serum Concentrations of Various Putative Peptidome Cancer Biomarkers
Shielding the cationic charge of nanoparticle-formulated dermal DNA vaccines is essential for antigen expression and immunogenicity
Altered cyclophosphamide and thiotepa pharmacokinetics in a patient with moderate renal insufficiency
All publications..

Current research

(the most recent research is at the top)
Project leader Prediction of pharmacokinetic interactions between complementary, alternative medicines and (new) anticancer drugs
Project leader OATP1A/1B (SLCO1A/1B) drug uptake transporters in anticancer drug pharmacokinetics and toxicity risks; possible strategies for therapy optimization
Project leader Biomedical Analysis : Functional and structural characterization
Project leader Slotervaart HIV cohort study - Part II: Pharmacokinetics and -genetics of highly active antiretroviral therapy (HAART) in HIV infection

Completed research projects

(the most recent research is at the top)
Project leader The impact of OATP drug carriers on in vivo pharmacology toxicology & physiology
Project leader Preclinical and clinical pharmacology of oral drugs
Project leader Generation and validation of cytochrome P450 3A knockout and transgenic mice as tools for improved drug development and research
Project leader Biomarker detection for primary breast cancer by serum and tissue protein
Project leader Prevention and therapy of tumors
All completed research..

Classification

A34800 Drugs and pesticides
D23340 Biopharmacology, toxicology

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