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Prof.dr. A.J.M. Driessen

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Expertise Mechanisms and energetics of solute and protein transport across biological membranes; Purification and reconstitution of membrane proteins and membrane protein complexes in liposomes; Analysis of the catalytic and energetic mechanisms; Protein-protein interactions by various biophysical techniques
Expertise (NL) Mechanisme en energetica van substraat en eiwittransport door biologische membranen; Zuivering en reconstitutie van membraaneiwitten (en complexen) in liposomen; Analyse van katalytische en energie-koppelingsmechanismen; Eiwit-eiwit interacties met behoefte van biofysische technieken
Digital Author ID info:eu-repo/dai/nl/073293830
KNAW member Science Division

Active as

Professor
Organisation Groningen Biomolecular Sciences and Biotechnology Institute - GBB (RUG)
Chair (EN) Molecular microbiology
Chair (NL) Moleculaire microbiologie
Phone +31-50-3632164
Email a. j. m. driessen -at- rug. nl
URL http://www.rug.nl/staff/a.j.m.driessen
Management
Organisation Groningen Biomolecular Sciences and Biotechnology Institute - GBB (RUG)
Email a. j. m. driessen -at- rug. nl

Publications

(the most recent at the top)
Protein Translocation at the Single Molecule Level
Protein Translocation at the Single Molecule Level
Analysis of the inhibition potential of zosuquidar derivatives on selected bacterial and fungal ABC transporters
Protein conducting channels—mechanisms, structures and applications
Biosynthetic concepts for the production of β-lactam antibiotics in Penicillium chrysogenum
All publications..

Current research

(the most recent research is at the top)
Project leader AntiBioScreen - Antimicrobial discovery in filamentous fungi
Researcher Awakening The Sleeping Lantibiotics
Researcher Education and research on Synthetic Biology for Advanced Metabolic Engineering
Project leader Capture and Release of Polypeptides by the Bacterial Translocation Pore
Project leader Assembly and function of pili in gene transfer and biofilm formation in Sulfolobus solfataricus
All current research..

Completed research projects

(the most recent research is at the top)
Project leader Protein translocation and membrane protein assembly
Project leader Coordinated SecA motor and SecYEG channel opening mechanisms during protein translocation
Supervisor Trans reentrant loop structures in secondary transporters
Supervisor The effect of secB on protein folding. A single molecule study
Project leader Translocase mediated biogenesis and assembly of the F0-sector of the F1F0-ATPase
All completed research..

Classification

C10000 Biotechnology
D13200 Macromolecular chemistry, polymer chemistry
D21200 Biophysics, clinical physics
D21300 Biochemistry
D22100 Microbiology

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