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Prof.dr. J.A. Schalken

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Expertise Molecular and cellbiology of oncological diseases; Cadherine mediated interactions and signal transductions; Molecular diagnostics; Urogenital oncology; Veterinary oncology
Expertise (NL) Moleculaire en celbiologie van oncologische aandoeningen; Cadherine gemedieerde interacties en signaaltransductie; Moleculaire diagnostiek; Urogenitale oncologie; Veterinaire oncologie
Email J. Schalken -at- ncmls. kun. nl
Digital Author ID info:eu-repo/dai/nl/07312804X
Addition Hoofd research urologie AZN; Voorzitter European society urological research; Secretaris Urological research society; Secretaris Nederlandse vereniging van celbiologie; Voorzitter stichting ter bevordering van wetenschappelijk urologisch onderzoek; Member editorial board European urology, urological research, world J. Urology, prostate cancer and diseases

Active as

Professor
Organisation Department of Urology (RU)
Chair (EN) Experimental urology
Chair (NL) Experimentele urologie
Email J. Schalken -at- uro. umcn. nl
URL http://www.umcn.nl/scientist/afdelingen/urologie/faculty/pro...

Publications

(the most recent at the top)
Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer.
Molecular diagnosis of prostate cancer: PCA3 and TMPRSS2:ERG gene fusion.
Aldo-keto reductase family 1 member C3 (AKR1C3) is a biomarker and therapeutic target for castration-resistant prostate cancer
PD-1 blockade augments Th1 and Th17 and suppresses Th2 responses in peripheral blood from patients with prostate and advanced melanoma cancer.
Personalized cancer therapy for urological cancers: from bench to bedside and back
All publications..

Completed research projects

(the most recent research is at the top)
Supervisor Renal Cell Carcinoma; risk factors and von-Hippel-Lindau gene mutations
Project leader Molecular diagnosis of prostate cancer using DD3/PCA3
Project leader Assessment of the diagnostic, prognostic and therapeutic usefulness of DD3 for prostate cancer.
Supervisor Models for prostate cancer. Molecular characterization and critical appraisal of humane prostate carcinoma cell lines

Classification

A22000 Animal husbandry
A70000 Public health and health care
C10000 Biotechnology
D23120 Oncology
D23227 Urology

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