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Person

Prof.dr. E. Vellenga

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Expertise	Internal medicine; haematology
Expertise (NL)	Inwendige geneeskunde; haematologie
Digital Author ID	info:eu-repo/dai/nl/069631050

Active as

Professor
Organisation	Department of Internal Medicine (RUG)
Chair (EN)	Internal medicine; haematology
Chair (NL)	Inwendige geneeskunde; haematologie
Phone	+31-50-3612933
Email	E. Vellenga -at- int. umcg. nl

Enhanced publications

Doctoral Thesis: Characterization of signal transduction pathways regulating myelopoiesis

Current research

(the most recent research is at the top)
Project leader	The role of autophagy in hematopoietic stem cell functionality and development of myelodysplasia (MDS)
Project leader	Randomized maintenance therapy with Azacitidine (Vidaza) in older patients (>60 years of age) with acute myeloid leukemia (AML) and refractory anemia with excess of blasts (RAEB, RAEB-t) (HOVON 97 AML study)
Project leader	A chronic myeloproliferative syndrome induced by the Polycomb Group gene Ezh2: mechanisms and interventions
Project leader	The involvement of NPM mutations and E-Cadherin in the development of AML
Project leader	Factors involved in megakaryocyte development.

All current research..

Completed research projects

(the most recent research is at the top)
Supervisor	Characterization of signal transduction pathways regulating myelopoiesis
Supervisor	Aberrant signal transduction and protein expression in acute myeloid leukemia
Project leader	Anti-CD 20 treatment of relapsed or refractory immune thrombocytopenic purpura (ITP) after first line corticosteriod treatment
Project leader	Characterization of signaling defects in granulocytes and myeloid precursor cells from myelodysplasia patients: its relation to apoptosis
Project leader	The role of fibroblast growth factor-1 and its receptor, Fgfr-1, in the regulation of normal and malignant haematopoietic stem cell numbers

All completed research..

Classification

D23221	Blood and lymphatic diseases

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