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Prof.dr. O.P. Kuipers Person

Prof.dr. O.P. Kuipers

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Expertise Gram-positive bacteria; Lactic acid bacteria; Industrial micro-organisms; Pathogenic bacteria; Biotechnology; Functional genomics; Gene regulation; Bacteriocins; Protein engineering; Controlled gene expression; Metabolic engineering; Lactococcus lactis; Bacillus subtilis; Streptococci; DNA-microarrays; Homologous and heterologous gene expression; Protein secretion; Lytic systems; Sugar metabolism
Expertise (NL) Gram-positieve bacteriën; Melkzuurbacteriën; Industriële micro-organismen; Pathogene bacteriën; Biotechnologie; Functional genomics; Genregulatie; Bacteriocines; Protein engineering; Gecontroleerde genexpressie; Metabole engineering; Lactococcus lactis; Bacillus subtilis; Streptococci; DNA-microarrays; Homologe en heterologe genexpressie; Eiwitsecretie; Lytische systemen; Suiker metabolisme
Digital Author ID info:eu-repo/dai/nl/07965391X
KNAW member Science Division
Addition Bestuurslid onderzoeksschool GBB, RUG; Lid dagelijks bestuur Genetica Cluster RUG; Apparatuurcommissie ALW/NWONWO; Commissielid Biomoleculaire Informatica

Active as

Professor
Organisation Groningen Biomolecular Sciences and Biotechnology Institute - GBB (RUG)
Chair (EN) Genetics of gram-positive bacteria
Chair (NL) Moleculaire genetica van prokaryoten
Phone +31-50-3632093
Email o. p. kuipers -at- rug. nl
URL http://www.rug.nl/staff/o.p.kuipers

Publications

(the most recent at the top)
Biofilm formation and dispersal in Gram-positive bacteria
Understanding microbial behavior within and outside the host to improve food functionality and safety
Increased D-alanylation of lipoteichoic acid and a thickened septum are main determinants in the nisin resistance mechanism of Lactococcus lactis
Assessment of CcpA-mediated carbolite control of gene expression in Bacillus Cereus ATCC 14579
Improvement of Lactobacillus Plantarum aerobic growth as directed by comprehensive transcriptome analysis
All publications..

Current research

(the most recent research is at the top)
Project leader Optimizing growth rate, biomass and product formation of Lactococcus lactis by a Systems Biology approach
Project leader Lipid engineering and -modulation to improve protein secretion by Bacillus subtilis
Researcher Understanding preculture-dependent growth and acidification rates of Lactococcus lactis as the result of population heterogeneity
Project leader Awakening The Sleeping Lantibiotics
Project leader Synthetic biology to obtain novel antibiotics and optimized production systems (SYNMOD)
All current research..

Completed research projects

(the most recent research is at the top)
Supervisor Protein secretion via the Twin-arginine translocation pathway of Bacillus subtilis
Researcher Integrative bioinformatics with data model enabled data analysis: test case industrial microorganisms
Project leader CcpA and the regulation of lactose metabolism in Streptococcusthermophilus
Project leader Secretome dynamics
Project leader Nutra cells workpackage 2 - Galactose and/or lactose removal from dairy products
All completed research..

Classification

A71000 Nutrition
C10000 Biotechnology
D21300 Biochemistry
D21400 Genetics
D22100 Microbiology

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