Prof.dr. J.H.M. Schellens

Update Persondata

• breast
• cancer
• cells
• clinical
• drugs
• medicine
• mice
• risk
• toxicology
• treatment
• tumor

Active as

Publications

(the most recent at the top)

Specific Investigation of Sample Handling Effects on Protease Activities and Absolute Serum Concentrations of Various Putative Peptidome Cancer Biomarkers

Cisplatin-DNA adduct formation in patients treated with cisplatin-based chemoradiation: lack of correlation between normal tissues and primary tumor

Current research

(the most recent research is at the top)
Project leader	Clinical Pharmacology
Project leader	Biomedical Analysis : Functional and structural characterization

Completed research projects

(the most recent research is at the top)
Researcher	Generation and validation of cytochrome P450 3A knockout and transgenic mice as tools for improveddrug development and research.
Project leader	Prediction of pharmacokinetic interactions between complementary, alternative medicines and (new) anticancer drugs
Project leader	Preclinical validation of chemical inhibitors of poly(ADP-ribose) polymerase (PARP) in conditional mouse models for BRCA-associated breast cancer
Project leader	Preclinical and clinical pharmacology of oral drugs
Project leader	Prevention and therapy of tumors

All completed research..

Classification

A34800	Drugs and pesticides
D23340	Biopharmacology, toxicology