Dr. R.A. Woutersen

Update Persondata

• experimental
• oncology
• pathobiology
• pathology
• toxicological
• toxicology

Publications

(the most recent at the top)

Toward relevant biomarkers in in vitro developmental toxicity and their extrapolation to the in vivo situation (in press)

The respiratory allergen glutaraldehyde in the local lymph node assay: Sensitization by skin exposure, but not by inhalation

A physiologically-based kinetic model for the prediction of plasma cholesterol concentrations in the mouse

The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-respomse curves for in vivo developmental toxicity of glycol ethers in rat and man

Systematic construction of a conceptual minimal model of plasma cholesterol levels based on knockout mouse phenotypes knockout mouse phenotypes

All publications..

Current research

(the most recent research is at the top)
Project leader	Risk of inhaled low molecular wight contact allergens
Supervisor	Risk of inhaled low molecular wight contact allergens
Supervisor	Implementation of (Q)SAR and physiologically-based kinetic (PBK) modeling techniques into a (Q)SAR-PBK approach for predicting dose-response relationships for rat and human and deriving safe exposure

Completed research projects

(the most recent research is at the top)
Co-supervisor	Zebrafish as an alternative model for (developmental) toxicitytesting.
Co-supervisor	Benefit-risk evaluation of flavonoids in foods and their use as functional food ingredients, task 4
Project leader	Nutrition in relation to health

Classification

A34600	Foods and stimulants
A71000	Nutrition
C10000	Biotechnology
D22600	Zoology
D23120	Oncology
D23340	Biopharmacology, toxicology