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Person

Prof.dr. A.C. Begg

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Expertise Cell kinetics; Predictive assays for radiotherapy outcome; Mechanisms of radiosensitivy; Hypoxia
Expertise (NL) Celkinetiek; Hypoxie; Voorspellende assays voor uitkomst na radiotherapie; Mechanismen van stralingsgevoeligheid
Digital Author ID info:eu-repo/dai/nl/298200546
Addition Hoofd divisie Experimentele Therapie; Lid wetenschappelijke raad KWF

Active as

Extraordinary professor
Organisation Department of Radiation Oncology (RU)
Chair (EN) Molecular radiobiology
Chair (NL) Moleculaire radiobiologie
Email a. begg -at- nki. nl
URL http://organisatiegids.ru.nl/tabOnderzoek.aspx?RBSID=364367

Publications

CD44 expression predicts local recurrence after radiotherapy in larynx cancer.
HPV and high-risk gene expression profiles predict response to chemoradiotherapy in head and neck cancer, independent of clinical factors.
Targeted radiosensitization of cells expressing truncated DNA polymerase {beta}.
Targeting base excision repair as a sensitization strategy in radiotherapy.
Radiobiology: state of the present art. A conference report.
All publications..

Current research

(the most recent research is at the top)
Project leader Prediction of local control after radiotherapy in head and neck cancer

Completed research projects

(the most recent research is at the top)
Project leader Prevention and therapy of tumors
Project leader Hypoxia and perfusion in human tumors: quantification and implications for treatment outcome
Project leader Determinants of radiosensitivity in mammalian cells: elucidating mechanisms using a putative dominant negative to DNA polymerase beta

Classification

A70000 Public health and health care
D23120 Oncology
D23330 Radiology, radiotherapy

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