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Prof.dr. J.J. Neefjes Person

Prof.dr. J.J. Neefjes

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Expertise Cell biology of antigen processing and presentation
Expertise (NL) Celbiologie van antigen processing en presentatie
Addition Bijzonder hoogleraar vanwege de Vereniging 'Het Nederlands Kanker Instituut'|Sectieleider afdeling Tumor Biologie

Active as

Extraordinary professor
Organisation Department of Immunohematology and Blood Transfusion (UL)
Chair (EN) Biology of antigen processing and presentation
Chair (NL) Biologie van antigen processing en presentatie
Phone +31-20-5121977
Email j. neefjes -at- nki. nl
URL http://www.LUMC.nl/0000/12296/hoo/
Researcher
Organisation The Netherlands Cancer Institute
Chair (EN) Cell biology of antigen processing and presentation
Chair (NL) Celbiologie van antigen processing en presentatie
Phone +31-20-5121977
Email j. neefjes -at- nki. nl

Current research

(the most recent research is at the top)
Supervisor Inhibitors of the human kinase PKB/Akt: conceptually new antibiotics
Project leader Manipulating the MHC class II system to control immune responses in autoimmunity
Project leader Physiological role of EBV-LMP1 in MHC-II+exosomes for tumor immune escape across the immunological synaps:Implications for prognosis and immunotherapy
Project leader Anti-cancer drugs and their effects on the ubiquitin cycle
Project leader Biosynthesis and function of base J, a new base in the nuclear DNA of kinetoplastid parasites

Completed research projects

(the most recent research is at the top)
Supervisor Molecular dissection of nuclear pathways in the nuclear pore complex in relation to nuclear export pathways
Project leader TPPII and the role in antigen presentation by MHC class I molecules
Project leader Molecular basis of resistance to anti-estrogens in estrogen-receptor positive breast cancer
Project leader On the molecular mechanisms of cross-presentation and priming for an efficient anti-tumor immune response
Project leader Peptidases and improving the MHC class I immune response
All completed research..

Classification

A70000 Public health and health care
D21500 Histology, cell biology
D21800 Immunology, serology
D23120 Oncology

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