KNAW

Back to search results
Person

Prof.dr. J. Borst

Pagina-navigatie:


Update Persondata


Expertise Experimental oncology
Expertise (NL) Experimentele oncologie
Email jborst -at- nki. nl
Digital Author ID info:eu-repo/dai/nl/304344443
Addition Bijzonder hoogleraar vanwege de Vereniging 'Het Nederlands Kanker Instituut' / Antoni van Leeuwenhoekziekenhuis; SILS Afdeling Biologie

Active as

Extraordinary professor
Organisation Swammerdam Institute for Life Sciences - SILS (UvA)
Chair (EN) Experimental oncology
Chair (NL) Experimentele oncologie
Phone +31-20-5122056
Email j. borst -at- uva. nl
Programm leader / Group leader
Organisation The Netherlands Cancer Institute
Email j. borst -at- nki. nl
URL http://www.nki.nl/ShowObject.asp?NodeID=2494

Publications

Regulation of translesion synthesis polymerases during somatic hypermutation and DNA damage tolerance
Molecular regulation of death receptor- and DNA damage-induced apoptosis
Molecular mechanisms underlying CD27-CD70 costimulation
Combining radiotherapy with death ligands in cancer treatment : feasibility and molecular mechanisms
CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome
All publications..

Current research

(the most recent research is at the top)
Project leader A novel type of ubiquitination regulates apoptosis signaling by BH3-only protein Bid.
Project leader Impact of TRAIL death receptor trafficking on pro-apoptotic signaling
Project leader T cell programming at the dendritic cell interface: impact on anti-tumor immunity
Project leader Biosynthesis and function of base J, a new base in the nuclear DNA of kinetoplastid parasites

Completed research projects

(the most recent research is at the top)
Supervisor Molecular mechanisms underlying CD27-CD70 costimulation
Project leader Manipulation of the CD70 locus to monitor and modulate the anti-tumor immune response and tumor development
Project leader Tumor therapy with ionizing radiation and death ligand trail: efficacy and key molecular determinants
Project leader Improving anti-tumor immunity via TNF receptor family member CD27 and its ligand
Project leader Communication to the mitochondria in apoptosis signaling by death receptors and DNA damaging regimens

Classification

D21200 Biophysics, clinical physics
D23120 Oncology

Go to page top
Go back to contents
Go back to site navigation