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Prof.dr. M.S. van Lohuizen Person

Prof.dr. M.S. van Lohuizen

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Expertise Biology of stem cells and cancer stem cells Epigenetics Regulation of cell cycle and oncogenesis
Expertise (NL) Biologie van stamcellen en kankerstamcellen Epigenetica Regulatie van celcyclus en oncogenese
Digital Author ID info:eu-repo/dai/nl/128359900
Addition Extraordinary professor, Division Neurogenetics, Academic Medical Hospital/University of Amsterdam. Head, division of Molecular Genetics, The Netherlands. Cancer Institute

Active as

Programm leader / Group leader
Organisation The Netherlands Cancer Institute
Phone +31-20-5122030
Email m. v. lohuizen -at- nki. nl
URL http://www.nki.nl/nkidep/lohuizenweb/
Extraordinary professor
Organisation Division of Medical Oncology (UvA)
Chair (EN) Biology and epigenetic regulation of normal and cancer stem cells
Chair (NL) Biologie en epigenetische regulatie van normale en kanker stamcellen
Phone +31-20-5122030
Email m. v. lohuizen -at- nki. nl
URL http://www.nki.nl/nkidep/lohuizenweb/

Current research

(the most recent research is at the top)
Project leader Deciphering the Role of Bmi1 and Ezh2 Polycomb group genes in Prostate Carcinogenesis and Metastasis
Project leader Potential oncogens and functioning of gene-receptor TBX2
Project leader Epigenetic regulation by the deubiquitinating enzyme USP3: impact on genome stability and tumorigenesis
Project leader Cancer stem cells and breast cancer: a polycomb connection?
Project leader Structural and functional analysis of a novel E3 ubiquitin ligase consisting of the polycomb proteins Bmi1 and Ring1b (RNF2)
All current research..

Completed research projects

(the most recent research is at the top)
Supervisor Dynamic and static interactions between the nuclear lamina and the genome
Project leader Investigating the role of the Polycomb-group gene Bmi1 in medulloblastomas and in neural cancer stem cell maintenance
Project leader Efficient in vitro genetic screens to identify new oncogenes involved in tumor progression
Project leader Characterization of oncogenic potential and mechanism of gene-repression of TBX2
Project leader Functional analysis of Bmi1-RING finger interacting proteins and application of microarray technology to identify Bm1-responsive genes
All completed research..

Classification

D21400 Genetics
D21500 Histology, cell biology
D23120 Oncology

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