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Prof.dr. R.M.A. Heeren Person

Prof.dr. R.M.A. Heeren

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Expertise The fundamental studies of the energetics of macromolecular systems, conformational studies of non-covalently bound protein complexes, virtual laboratory technology and the development and validation of new mass spectrometry based proteomic imaging techniques for the life sciences
Expertise (NL) The fundamental studies of the energetics of macromolecular systems, conformational studies of non-covalently bound protein complexes, virtual laboratory technology and the development and validation of new mass spectrometry based proteomic imaging techniques for the life sciences
Digital Author ID info:eu-repo/dai/nl/105188476

Active as

Programm leader / Group leader
Organisation FOM Institute AMOLF (NWO)
Email R. Heeren -at- amolf. nl
URL http://www.amolf.nl/people/amolf-person/chash/6a606b7426/per...
Professor
Organisation Department of Biomolecular Mass Spectrometry and Proteomics (UU)
Chair (EN) Physical aspects of the biomolecular mass spectrometry
Chair (NL) Fysische aspecten van de biomoleculaire massaspectrometrie
Phone +31-20-6081234
Email R. M. A. Heeren -at- uu. nl
URL http://www.pharm.uu.nl/ffwuk.htm?/bioms/members/Ron_Heeren.h...

Publications

(the most recent at the top)
High-resolution MALDI imaging mass spectrometry allows localization of peptide distributions at cellular length scales in pituitary tissue sections
Imaging of Peptides in the Rat Brain Using MALDI-FTICR Mass Spectrometry
Disulfide bond cleavages observed in SORI-CIS of three nonapeptides complexed with divalent transition-metal cations
Tools and strategies for visualization of large image datasets in high-resolution imaging mass spectrometry
Identification of leptomeningeal metastasis-related proteins in cerebrospinal fluid of patients with breast cancer by a combination of MALDI-TOF, MALDI-FTICR and nanoLC-FTICR MS
All publications..

Current research

(the most recent research is at the top)
Project leader Analysis of minimal residual disease and therapy resistance in primary tumor xenograft models of triple-negative breast cancer
Project leader Miniaturizing Mass Spectrometry, Bringing Mass Spectrometry to Daily life

Completed research projects

(the most recent research is at the top)
Project leader FTMS trajectory calculations
Researcher Proteomics based biomarkers for clinical research
Project leader Biomolecular imaging mass spectrometry
Supervisor Addressing the influence of charged plasma effects in the Penning traps on mass accuracy measurements by Fourier transform ion cyclotron resonance mass spectrometer

Classification

D12100 Metrology, scientific instrumentation
D12600 Atomic and molecular physics
D13100 Analytical chemistry
D21200 Biophysics, clinical physics

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