Prof.dr. Y. Elgersma

Update Persondata

• basis
• cellular
• memory
• molecular
• neuroscience

Active as

Publications

(the most recent at the top)

Intrinsic plasticity complements long-term potentiation in parallel fiber input gain control in cerebellar Purkinje cells

Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice

betaCaMKII controls the direction of plasticity at parallel fiber–Purkinje cell synapses

Spred1 is required for synaptic plasticity and hippocampus-dependent learning

Neurofibromin Regulation of ERK Signaling Modulates GABA Release and Learning

All publications..

Current research

(the most recent research is at the top)
Project leader	Optogenetically Enhanced Multipatch Neurophysiology: Defining the physiology of experience-dependent plasticity by targeted mapping of neural circuits
Project leader	D-phenylalanine as a possible treatment of neurological problems in Tuberous Sclerosis Complex (TSC)
Project leader	Molecular and cellular mechanisms underlying learning and mental retardation

Completed research projects

(the most recent research is at the top)
Supervisor	The role of the TSC-Rheb pathway in synaptic plasticity, learning and social behavior
Project leader	The role of accumulated DNA damage in cognitive decline: Potential mouse models for accelerated aging of the brain
Project leader	Simvastatin effect on the cognitive problems of children suffering from neurofibromatosis type 1 (NF1)
Project leader	Pre- and postsynaptic mechanisms controlling hippocampal and cerebellar memory formation
Project leader	Molecular mechanisms underlying hippocampal and cerebellar learning

Classification

D21300	Biochemistry
D21500	Histology, cell biology
D23231	Neurology