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Prof.dr.ir. B.M.T. Burgering Person

Prof.dr.ir. B.M.T. Burgering

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Expertise Signal transduction
Expertise (NL) Signaaltransductie
Digital Author ID info:eu-repo/dai/nl/081474547
Grants/prizes NWO-Vici 2002

Active as

Professor
Organisation Department of Molecular Cancer Research (UU)
Chair (EN) Signal transduction
Chair (NL) Signaaltransductie
Phone +31-88-7568918
Email b. m. t. burgering -at- umcutrecht. nl
URL http://www.umcutrecht.nl/subsite/Professors/Divisions/Biomed...

Publications

Activation of forkhead box O transcription factors by oncogenic BRAF promotes p21cip1-dependent senescence
Activation of FoxO transcription factors contributes to the antiproliferative effect of cAMP
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)
Regulation of sterol carrier protein gene expression by the forkhead transcription factor FOXO3a
Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty
All publications..

Current research

(the most recent research is at the top)
Project leader The role of the small GTPase Ral in the control of FOXO transcription factors and cell transformation.
Project leader Beta-catenin control of FOXO signalling and the regulation of TCF signalling

Completed research projects

(the most recent research is at the top)
Supervisor The role of the PI3K/PKB/Forkhead pathway in cell fate control and disease
Project leader Intermediates in the signalling pathway from Ras-Ral to transcription factors
Project leader Signal transduction by small GTPases of the Ras family and by protein kinase B (PKB)
Project leader Control of cellular proliferation in normal and tumor cells by the P13K/PKB/Forkhead pathway
Supervisor Analysis of the Protein Kinase B - Forkhead box O signaling pathway

Classification

D21300 Biochemistry

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