Prof.dr. F.C.P. Holstege

Update Persondata

• expression
• gene
• genome
• genomics
• level
• mechanisms
• molecular
• regulation
• wide

Active as

Publications

(the most recent at the top)

Gene Expression Profiling of early intervertebral disc degeneration

Tight control of MEK-ERK activation is essential in regulating proliferation, survival, and cytokine production of CD34+-derived neutrophil progenitors

Nitric oxide donor induces temporal and doce-dependent reduction of gene expression in human endothelial cells

Enhanced publications

(the most recent at the top)

Doctoral Thesis: Analysis of Genome-Scale Data

Current research

(the most recent research is at the top)
Project leader	Understanding how specificity in transcription is achieved through modification of the global coregulator Mediator: a combined proteomics and genomics approach
Project leader	A genome control map of expression-profile phenotypes

Completed research projects

(the most recent research is at the top)
Supervisor	Genome-wide expression analysis of transcription regulatory complexes
Project leader	A modular storage and analysis pipeline for quality control, analysis and MAGE-NL export of microarray data
Researcher	Unifying framework for data-driven pathway discovery
Project leader	A gene expression signature for prediction of disease free survival after R0 resection of colorectal liver metastasis
Project leader	Gene expression profiling for assessment of lymph node metastasis in head and neck squamous cell cancer.

All completed research..

Classification

D21300	Biochemistry
D21400	Genetics