Prof.dr. W. Jiskoot

Update Persondata

• biopharmaceuticals
• delivery
• drug
• formulation
• immunogenicity
• protein
• stability
• technology
• vaccines

Active as

Publications

(the most recent at the top)

Quality of Original and Biosimilar Epoetin Products

PLGA, PLGA-TMC and TMC-TPP nanoparticles differentially modulate the outcome of nasal vaccination by inducing tolerance or enhancing humoral immunity

Chitosan-based delivery systems for protein therapeutics and antigens

Hybrid transgenic immune tolerant mouse model for assessing the breaking of B cell tolerance by human interferon beta

Immunological mechanism underlying the immune response to recombinant human protein therapeutics

All publications..

Enhanced publications

(the most recent at the top)

Doctoral Thesis: Towards an intranasal influenza vaccine based on whole inactivated influenza virus with N,N,N-trimethyl chitosan as adjuvant

Current research

(the most recent research is at the top)
Researcher	Non-invasive transcutaneous vaccination by means of coated microneedles and microjets
Supervisor	The use of physicochemical and immunochemical assays to study antigen-adjuvant interactions for prediction of quality of diphtheria and tetanus toxoid vaccines
Project leader	Stabilisation of therapeutic proteins by supercritical fluid drying technologies II

Completed research projects

(the most recent research is at the top)
Project leader	The development and validation of immune tolerant mouse models to measure and predict the immunogenicity of monoclonal antibody (MAb) therapeutics
Supervisor	Immunogenicity of recombinant interferon beta aggregates; Mechanistic studies in transgenic immune tolerant mice
Supervisor	Transcutaneous subunit vaccine delivery
Supervisor	Towards an intranasal influenza vaccine based on whole inactivated influenza virus with N,N,N-trimethyl chitosan as adjuvant
Supervisor	Formulation of stable protein powders by supercritical fluid drying

Classification

D21800	Immunology, serology
D23340	Biopharmacology, toxicology