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Person

Dr. J. Cloos

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Active as

Researcher
Organisation	Department of Pediatric Surgery (VU)
Email	j. cloos -at- vumc. nl

Current research

(the most recent research is at the top)
Project leader	Application of bortezomib in pediatric acute lymphoblastic leukemiaChildhood relapsed ALL remains a significant problem in pediatric oncology, therefore novel drugs with a new mechanism of action are needed to improve prognosis. The proteasome inhibitor bortezomib (PS341, Velcade®, BTZ) represents a
Project leader	Retinoblastoma research
Project leader	Mutagen sensitivity: clinical relevance and underlying mechanism

Completed research projects

(the most recent research is at the top)
Researcher	Cell biological characteristics, drug resistance and clinical studies in pediatric oncology
Project leader	Drug resistance in childhood leukemia
Project leader	Characterization of relapsed acute myeloid leukemia
Researcher	Targeted therapy in pediatric brain tumors
Project leader	Innovative therapy for childhood brain tumors

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