Dr. N.G.J. Jaspers

Update Persondata

• activity
• enzyme
• exposure
• gene
• lesions
• mutation
• patients
• repair
• transcription

Active as

Publications

(the most recent at the top)

Mislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patients

A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation

The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA insterstrand cross-link-induced double-strand breaks

Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways.

Molecular mechanism of nucleotide excision repair

All publications..

Current research

(the most recent research is at the top)
Researcher	Nucleotide Excision Repair

Completed research projects

(the most recent research is at the top)
Project leader	Microarray analysis of the response of the genome upon exposure to UV using genetically defined mouse models for DNA repair