Prof.dr. D.E. Grobbee

Update Persondata

• global
• health
• international
• sciences

Active as

Publications

(the most recent at the top)

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

Potential misinterpretation of treatment effects due to use of odds ratios and logistic regression in randomized controlled trials

Long-term outcome of open or endovascular repair of abdominal aortic aneurysm

Mortality in adult congenital heart disease

All publications..

Enhanced publications

(the most recent at the top)

Doctoral Thesis: Prognosis, proof and priorities in dietetic practice

Doctoral Thesis: Depression and Diabetes - Methodological Issues in Etiologic Research

Current research

(the most recent research is at the top)
Project leader	Circulatory Health
Project leader	UMPIRE : Use of a Multidrug Pill In Reducing cardiovascular Events A randomised controlled trial of fixed-dose combination medication and usual care in those at high risk of cardiovascular disease
Project leader	The Mondriaan Project: The Dutch healthcare landscape as a 'population laboratory'
Project leader	A combined diagnostic-therapeutic strategy to optimize management of patients with previously unrecognized heart failure in primary care
Project leader	Advancements in the DESIGN, conduct and analysis of randomised trials on drug effects

Completed research projects

(the most recent research is at the top)
Supervisor	Imaging of atherosclerosis: study design and cardiovascular risk prediction
Project leader	Optimising the benefits and SAFETY of new drugs: prospects pharmacogenetics/-genomics, safety monitoring
Project leader	The (future) post-marketing phase: requirements and opportunities for better SAFETY research
Project leader	Use and validation of BIOMARKERS and proxy-outcomes in pre- and post-registration setting
Project leader	Connecting BIOMARKERS and proxy-outcomes across different phases of drug development

All completed research..

Classification

A71000	Nutrition
D22100	Microbiology
D23110	Infections, parasitology