Prof.dr. H.R. Delwel

Update Persondata

• insertional
• leukemia
• leukemogenesis
• models
• molecular
• mouse
• mutagenesis
• oncogenes
• proto
• retroviral
• transgenic

Active as

Publications

(the most recent at the top)

Risk stratification of intermediate-risk acute myeloid leukemia: Integrative analysis of a multitude of gene mutation and gene expression markers

Integrative prognostic risk score in acute myeloid leukemia with normal karyotype

Het zit 'm in het bloed

Pim2 cooperates with PML-RARα to induce acute myeloid leukemia in a bone marrow transplantation model

HAT: Hypergeometric Analysis of Tiling-arrays with application to promoter-GeneChip data

All publications..

Current research

(the most recent research is at the top)
Project leader	C/EBPA abnormalities in AML
Project leader	Aberrant EVI1 expression in mouse and human AML

Completed research projects

(the most recent research is at the top)
Project leader	An integrated molecular study of human acute myeloid leukemia (AML) with a specific focus on genome wide methylation in patients with aberrant EVI1 expression.
Project leader	Genome-wide approaches to identify novel clinically relevant markers in acute myeloid leukemia with normal karyotypes
Project leader	Acute myeloid leukemia with CEBPA aberrations: alpha-Catenin and other putative CEBPA targets in leukemic transformation
Project leader	Novel signaling defects identified in Graffi1.4-MuLV-induced acute myeloid leukemia (AML): functional consequences and clinical significance
Project leader	Aberrant expression of Nm23-M2 in myeloid leukemia through a novel mechanism: abnormal control of protein translation

All completed research..

Classification

A70000	Public health and health care
D23221	Blood and lymphatic diseases