Prof.dr. R. Pieters

Update Persondata

• cell
• drug
• expression
• gene
• genes
• mutations
• oncology
• pediatric
• resistance
• risk
• treatment

Active as

Publications

(the most recent at the top)

CBL mutations do not frequently occur in paediatric acute myeloid leukaemia

Elevated S100A8/S100A9 expression causes glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia

Different Outcome in Older Children With Acute Lymphoblastic Leukemia With Different Treatment Protocols in the Netherlands

Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia

In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia

All publications..

Enhanced publications

(the most recent at the top)

Doctoral Thesis: Molecular-genetic insights in pediatric T-cell acute lymphoblastic leukemia

Current research

(the most recent research is at the top)
Project leader	Discovering new oncogenic aberrations in T-cell acute lymphoblastic leukemia
Project leader	Identification of new cancer genes involved in lymphomagenesis
Project leader	Definition of risk groups in infant acute lymphoblastic leukemia by prospective analysis of immunobiological characteristics, genetic abnormalities, drug resistance and minimal residual disease
Project leader	Prediction of treatment outcome in infant acute lymphoblastic leukemia
Project leader	Molecular alterations in the reduced folate carrier gene, multidrug resistance protein-mediated efflux and folate compartmentation: impact on cellular folate homeostasis and activity of antifolate drugs in childhood leukemia

All current research..

Completed research projects

(the most recent research is at the top)
Supervisor	The Social Psychology of Envy: An inquiry into the causes and consequences
Project leader	Characterization of a novel BCRABL-like subtype with high relapse-risk in pediatric acute lymphoblastic leukemia
Project leader	Molecular diagnosis of polymorphism of cytochrome P450 isoenzymes for optimalisation of chemotherapy in childhood cancer
Supervisor	Chemotherapy Induced Intestinal Mucositis: from bench to bed
Supervisor	Endocrine Effects of the Treatment for Acute Lymphoblastic Leukemia and Hodgkin's Lymphoma in Childhood

All completed research..

Classification

D23120	Oncology
D23362	Pediatrics