Prof.dr. A.H.J. Danser

Update Persondata

• angiotensin
• components
• emphasis
• failure
• function
• heart
• hypertension
• local
• pathogenesis
• renin
• sites
• special
• synthesis
• system
• therapy
• tissue
• with

Active as

Publications

(the most recent at the top)

A Novel Splice-Site Mutation in Angiotensin I-Converting Enzyme (ACE) Gene, c.3691+1G>A (IVS25+1G>A), Causes a Dramatic Increase in Circulating ACE through Deletion of the Transmembrane Anchor

Impaired vascular contractility and aortic wall degeneration in fibulin-4 deficient mice: Effect of angiotensin II type 1 (AT1) receptor blockade

Effect of the calcitonin gene-related peptide (CGRP) receptor antagonist telcagepant in human cranial arteries

Characterization of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) in human isolated coronary arteries

Drug mechanisms to help in managing resistant hypertension in obesity

All publications..

Current research

(the most recent research is at the top)
Project leader	Renin-angiotensin system blockade beyond angiotensin II
Project leader	Hypertension, the kidney and vascular ageing: focus on the renin-angiotensin-aldosterone system

Completed research projects

(the most recent research is at the top)
Supervisor	(Pro)renin Revisited: New Insights from Studies in Mast Cells
Project leader	Pathogenesis and therapy of hypertension and heart failure: novel pathways and interventions in the renin-angiotensin system and the role of genomic instability
Project leader	Pharmacogenetic aspects of ACE inhibition in stable coronary artery disease
Project leader	The renin receptor: a new component of the renin-angiotensin system
Supervisor	Natriuretic Peptides, Diagnostic and Prognostic Biomakers

All completed research..

Classification

D23340	Biopharmacology, toxicology