Dr. D. Jaarsma

Update Persondata

• complexes
• expression
• lipid
• membrane
• mice
• motor
• network
• protein
• repair

Active as

Publications

(the most recent at the top)

Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice

Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry

Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes

A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice

Loss of Hoxb8 alters spinal dorsal laminae and sensory responses in mice

All publications..

Current research

(the most recent research is at the top)
Project leader	The role of vesicle-associated membrane protein (VAPB) and the disturbed lipid metabolism in ALS pathogenesis

Completed research projects

(the most recent research is at the top)
Project leader	The pathogenesis of amyotrophic lateral sclerosis (ALS)
Project leader	Dyneine transport in amyotrophic lateral sclerosis (ALS)
Project leader	Disturbance of motoneuron transport in amyotrophic lateral sclerosis (ALS)