Dr. P.J.M. Valk

Update Persondata

• alpha
• cell
• expression
• gene
• genes
• mutation
• patients
• receptor
• risk
• tumor
• viral

Publications

(the most recent at the top)

Risk stratification of intermediate-risk acute myeloid leukemia: Integrative analysis of a multitude of gene mutation and gene expression markers

Integrative prognostic risk score in acute myeloid leukemia with normal karyotype

Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia

The Antioxidant Protein Peroxiredoxin 4 Is Epigenetically Down Regulated in Acute Promyelocytic Leukemia

Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: Prevalence and prognostic value

All publications..

Current research

(the most recent research is at the top)
Project leader	Molecular diagnostics and gene expression profiling of hematologic diseases

Completed research projects

(the most recent research is at the top)
Project leader	Genome-wide approaches to identify novel clinically relevant markers in acute myeloid leukemia with normal karyotypes
Project leader	Acute myeloid leukemia with CEBPA aberrations: alpha-Catenin and other putative CEBPA targets in leukemic transformation
Project leader	Functional consequences of mutations in the receptor tyrosine kinase c-KIT in AML with inv(16)
Project leader	Novel signaling defects identified in Graffi1.4-MuLV-induced acute myeloid leukemia (AML): functional consequences and clinical significance