Dr. R.A. Willemsen

Update Persondata

• alpha
• antibodies
• beta
• cell
• class
• gene
• genes
• immune
• peptide
• production
• tumor

Publications

(the most recent at the top)

Chimeric immune receptors (CIRs) specific to JC virus for immunotherapy in progressive multifocal leukoencephalopathy (PML)

T cell re-targeting to EBV antigens following TCR gene transfer: CD28-containing receptors mediate enhanced antigen-specific IFNgamma production

CD8α Coreceptor to Improve TCR Gene Transfer to Treat Melanome: Down-Regulation of Tumor-Specific Production of IL-4, IL-5 and IL-10

T cell retargeting with MHC class I-restricted antibodies: the CD28 costimulatory domain enhances antigen-specific cytotoxicity and cytokine production

Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR alpha beta genes into primary human T lymphocytes

Current research

(the most recent research is at the top)
Project leader	Novel ligand-receptor systems with anti-tumor activities
Project leader	Adenoviral targetting to solid tumors

Completed research projects

(the most recent research is at the top)
Project leader	T cell retargeting to melanoma via gene transfer of MHC-restricted receptors