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  • Blood pressure and the susceptibility to renal damage after unilateral nephrectomy and L-NAME-induced hypertension in rats (2000)Open access

    Auteurs:Dokkum, van R.P.E. (Richard); Jacob, H.J.; Provoost, A.P. (Abraham)
    In:Nephrology, Dialysis, Transplantation. ISSN 0931-0509.

    Samenvatting:

    BACKGROUND: Fawn-hooded hypertensive (FHH) rats carry several genes which determine the susceptibility to develop renal damage, while renal damage resistant August x Copenhagen Irish (ACI) rats do not. Kidneys from heterozygous (FHH x ACI) F(1) rats, appear to be largel

  • Impaired autoregulation of renal blood flow in the fawn-hooded rat (1999)Open access

    Auteurs:Dokkum, van R.P.E. (Richard); Alonso-Galicia, M.; Provoost, A.P. (Abraham); Jacob, H.J.; Roman, R.J.
    In:American Journal of Physiology (Consolidated). ISSN 0002-9513.

    Samenvatting:

    The responses to changes in renal perfusion pressure (RPP) were compared in 12-wk-old fawn-hooded hypertensive (FHH), fawn-hooded low blood pressure (FHL), and August Copenhagen Irish (ACI) rats to determine whether autoregulation of renal blood flow (RBF) is altered in

  • Altered renal hemodynamics and impaired myogenic responses in the fawn-hooded rat (1999)Open access

    Auteurs:Dokkum, van R.P.E. (Richard); Sun, C.W.; Provoost, A.P. (Abraham); Jacob, H.J.; Roman, R.J.
    In:American Journal of Physiology (Consolidated). ISSN 0002-9513.

    Samenvatting:

    The present study examined whether an abnormality in the myogenic response of renal arterioles that impairs autoregulation of renal blood flow (RBF) and glomerular capillary pressure (PGC) contributes to the development of renal damage in fawn-hooded hypertensive (FHH)

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