Prof.dr. B.E. de Pauw

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A randomized, double-blind, multicenter study of caspofungin versus liposomal amphotericin B for empiric antifungal therapy in pediatric patients with persistent fever and neutropenia. (2010)

Authors:	Maertens, J.A.; Madero, L.; Reilly, A.F.; Lehrnbecher, T.; Groll, A.H.; Jafri, H.S.; Green, M.; Nania, J.J.; Bourque, M.R.; Wise, B.A.; Strohmaier, K.M.; Taylor, A.F.; Kartsonis, N.A.; Chow, J.W.; Arndt, C.A.; Pauw, B.E. de; Walsh, T.J.
In:	Pediatric Infectious Disease Journal, 29, 415 - 420. ISSN 0891-3668.

Abstract:

BACKGROUND: Persistently febrile neutropenic children at risk for invasive fungal infections receive empiric antifungal therapy as a standard of care. However, little is known about the role of echinocandins and liposomal amphotericin B (L-AmB) for empiric antifungal therapy in pediatric patients. M

Timely intervention for invasive fungal disease: should the road now lead to the laboratory instead of the pharmacy? (2009)

Authors: Pauw, B.E. de; Donnelly, J.P.
In: Clinical Infectious Diseases, 48, 1052 - 1054. ISSN 1058-4838.
A perspective on liposomal amphotericin B (AmBisome) (2008)

Authors: Richardson, M.; Pauw, B.E. de
In: Clinical Microbiology and Infection, 14, 1 - 4. ISSN 1198-743x.

Authors:	Pauw, B.E. de; Donnelly, J.P.
In:	Clinical Infectious Diseases, 48, 1052 - 1054. ISSN 1058-4838.

Authors:	Richardson, M.; Pauw, B.E. de
In:	Clinical Microbiology and Infection, 14, 1 - 4. ISSN 1198-743x.

Defining responses to therapy and study outcomes in clinical trials of invasive fungal diseases: Mycoses Study Group and European Organization for Research and Treatment of Cancer consensus criteria. (2008)

Authors:	Segal, B.H.; Herbrecht, R.; Stevens, D.A.; Ostrosky-Zeichner, L.; Sobel, J.; Viscoli, C.; Walsh, T.J.; Maertens, J.; Patterson, T.F.; Perfect, J.R.; Dupont, B.; Wingard, J.R.; Calandra, T.; Kauffman, C.A.; Graybill, J.R.; Baden, L.R.; Pappas, P.G.; Bennett, J.E.; Kontoyiannis, D.P.; Cordonnier, C.; Viviani, M.A.; Bille, J.; Almyroudis, N.G.; Wheat, L.J.; Graninger, W.; Bow, E.J.; Holland, S.M.; Kullberg, B.J.; Dismukes, W.E.; Pauw, B.E. de
In:	Clinical Infectious Diseases, 47, 674 - 683. ISSN 1058-4838.

Authors:

Segal, B.H.; Herbrecht, R.; Stevens, D.A.; Ostrosky-Zeichner, L.; Sobel, J.; Viscoli, C.; Walsh, T.J.; Maertens, J.; Patterson, T.F.; Perfect, J.R.; Dupont, B.; Wingard, J.R.; Calandra, T.; Kauffman, C.A.; Graybill, J.R.; Baden, L.R.; Pappas, P.G.; Bennett, J.E.; Kontoyiannis, D.P.; Cordonnier, C.; Viviani, M.A.; Bille, J.; Almyroudis, N.G.; Wheat, L.J.; Graninger, W.; Bow, E.J.; Holland, S.M.; Kullberg, B.J.; Dismukes, W.E.; Pauw, B.E. de

In:

Clinical Infectious Diseases, 47, 674 - 683. ISSN 1058-4838.

Abstract:

Invasive fungal diseases (IFDs) have become major causes of morbidity and mortality among highly immunocompromised patients. Authoritative consensus criteria to diagnose IFD have been useful in establishing eligibility criteria for antifungal trials. There is an important need for generation of cons

Erythrocyte vesiculation: a self-protective mechanism? (2008)

Authors:	Willekens, F.L.A.; Werre, J.M.; Groenen-Dopp, Y.A.; Roerdinkholder-Stoelwinder, B.; Pauw, B.E. de; Bosman, G.J.C.G.M.
In:	British Journal of Haematology, 141, 549 - 556. ISSN 0007-1048.

Abstract:

Previous studies demonstrated that 20% of haemoglobin is lost from circulating erythrocytes during their total lifespan by vesiculation. To study whether removal molecules other than membrane-bound haemoglobin were present in erythrocyte-derived vesicles, flow cytometry and immunoblot analysis were

Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. (2008)

Authors:	Pauw, B.E. de; Walsh, T.J.; Donnelly, J.P.; Stevens, D.A.; Edwards, J.E.; Calandra, T.; Pappas, P.G.; Maertens, J.; Lortholary, O.; Kauffman, C.A.; Denning, D.W.; Patterson, T.F.; Maschmeyer, G.; Bille, J.; Dismukes, W.E.; Herbrecht, R.; Hope, W.W.; Kibbler, C.C.; Kullberg, B.J.; Marr, K.A.; Munoz, P.; Odds, F.C.; Perfect, J.R.; Restrepo, A.; Ruhnke, M.; Segal, B.H.; Sobel, J.D.; Sorrell, T.C.; Viscoli, C.; Wingard, J.R.; Zaoutis, T.; Bennett, J.E.
In:	Clinical Infectious Diseases, 46, 1813 - 1821. ISSN 1058-4838.

Authors:

Pauw, B.E. de; Walsh, T.J.; Donnelly, J.P.; Stevens, D.A.; Edwards, J.E.; Calandra, T.; Pappas, P.G.; Maertens, J.; Lortholary, O.; Kauffman, C.A.; Denning, D.W.; Patterson, T.F.; Maschmeyer, G.; Bille, J.; Dismukes, W.E.; Herbrecht, R.; Hope, W.W.; Kibbler, C.C.; Kullberg, B.J.; Marr, K.A.; Munoz, P.; Odds, F.C.; Perfect, J.R.; Restrepo, A.; Ruhnke, M.; Segal, B.H.; Sobel, J.D.; Sorrell, T.C.; Viscoli, C.; Wingard, J.R.; Zaoutis, T.; Bennett, J.E.

In:

Clinical Infectious Diseases, 46, 1813 - 1821. ISSN 1058-4838.

Abstract:

BACKGROUND: Invasive fungal diseases are important causes of morbidity and mortality. Clarity and uniformity in defining these infections are important factors in improving the quality of clinical studies. A standard set of definitions strengthens the consistency and reproducibility of such studies.

Present situation in the treatment of invasive fungal infection. (2008)

Authors: Pauw, B.E. de; Picazo, J.J.
In: International Journal of Antimicrobial Agents, 32, S167 - S171. ISSN 0924-8579.

Abstract:
Recent advances have made it possible to treat successfully conditions that for many years were considered incurable. In many cases, aggressive therapeutic or diagnostic techniques have been used. One resulting adverse event is a severely diminished immune response that, given the patient's situatio
Comparison of two highly discriminatory molecular fingerprinting assays for analysis of multiple Aspergillus fumigatus isolates from patients with invasive aspergillosis. (2007)

Authors: Valk, H.A. de; Meis, J.F.G.M.; Pauw, B.E. de; Donnelly, J.P.; Klaassen, C.H.W.
In: Journal of Clinical Microbiology, 45, 1415 - 1419. ISSN 0095-1137.

Abstract:
Two highly discriminatory fingerprinting assays, short tandem repeat typing and amplified fragment length polymorphism (AFLP), were compared to determine the genetic relatedness between 55 isolates of Aspergillus fumigatus obtained from 15 different patients suffering from proven invasive aspergillo

Authors:	Pauw, B.E. de; Picazo, J.J.
In:	International Journal of Antimicrobial Agents, 32, S167 - S171. ISSN 0924-8579.

Authors:	Valk, H.A. de; Meis, J.F.G.M.; Pauw, B.E. de; Donnelly, J.P.; Klaassen, C.H.W.
In:	Journal of Clinical Microbiology, 45, 1415 - 1419. ISSN 0095-1137.

Autotransfusion management during and after cardiopulmonary bypass alters fibrin degradation and transfusion requirements. (2007)

Authors:	Wiefferink, A.; Weerwind, P.W.; Heerde, W.L. van; Teerenstra, S.; Noyez, L.; Pauw, B.E. de; Brouwer, R.M.H.J.
In:	Journal of Extra-Corporeal Technology, 39, 66 - 70. ISSN 0022-1058.

Abstract:

The coagulation-fibrinolytic profile during cardiopulmonary bypass (CPB) has been widely documented. However, less information is available on the possible persistence of these alterations when autotransfusion is used in management of perioperative blood loss. This study was designed to explore the

The value of randomized clinical trials for daily clinical practice. (2007)

Authors: Pauw, B.E. de; Rubin, R.H.
In: Transplant Infectious Disease, 9, 173 - 174. ISSN 1398-2273.

Authors:	Pauw, B.E. de; Rubin, R.H.
In:	Transplant Infectious Disease, 9, 173 - 174. ISSN 1398-2273.

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