Prof.dr. H.J. Blom

Pagina-navigatie:

Main
Completed research (5)
Publications (122)

filter results

Type

Date

Accessibility

Institution

81-90 out of 122 results by:date

Save search results

5,10-methylenetetrahydrofolate reductase (MTHFR) 677C-->T and 1298A-->C mutations are associated with DNA hypomethylation. (2004)

Authors: Castro, R.; Rivera, I.; Ravasco, P.; Camilo, M.E.; Jakobs, C.; Blom, H.J.; Almeida, I.T. de
In: Journal of Medical Genetics, 41, 454 - 458. ISSN 1468-6244.
The effect of homocysteine reduction by B-vitamin supplementation on markers of endothelial dysfunction. (2004)

Authors: Peeters, A.C.T.; Molen, E.F. van der; Blom, H.J.; Heijer, M. den
In: Thrombosis and Haemostasis, 92, 1086 - 1091. ISSN 0340-6245.

Abstract:
Hyperhomocysteinemia is a risk factor for arterial vascular disease and venous thrombosis. The pathophysiology of this relation is unclear, but several studies suggest that hyperhomocysteinemia impairs endothelial function. We examined the effect of homocysteine lowering by B-vitamin supplementation
Bioavailability of polyglutamyl folic acid relative to that of monoglutamyl folic acid in subjects with different genotypes of the glutamate carboxypeptidase II gene. (2004)

Authors: Melse-Boonstra, A.; Lievers, K.J.; Blom, H.J.; Verhoef, P.
In: American Journal of Clinical Nutrition, 80, 700 - 704. ISSN 0002-9165.

Abstract:
BACKGROUND: Before dietary folate is absorbed, polyglutamate folates are deconjugated to monoglutamates by folylpoly-gamma-glutamyl carboxypeptidase in the small intestine. The 1561T allele of the glutamate carboxypeptidase II gene (GCPII), which codes for folylpoly-gamma-glutamyl carboxypeptidase,

Authors:	Castro, R.; Rivera, I.; Ravasco, P.; Camilo, M.E.; Jakobs, C.; Blom, H.J.; Almeida, I.T. de
In:	Journal of Medical Genetics, 41, 454 - 458. ISSN 1468-6244.

Authors:	Peeters, A.C.T.; Molen, E.F. van der; Blom, H.J.; Heijer, M. den
In:	Thrombosis and Haemostasis, 92, 1086 - 1091. ISSN 0340-6245.

Authors:	Melse-Boonstra, A.; Lievers, K.J.; Blom, H.J.; Verhoef, P.
In:	American Journal of Clinical Nutrition, 80, 700 - 704. ISSN 0002-9165.

Folate, homocysteine levels, methylenetetrahydrofolate reductase (MTHFR) 677C --> T variant, and the risk of myocardial infarction in young women: effect of female hormones on homocysteine levels. (2004)

Authors:	Tanis, B.C.; Blom, H.J.; Bloemenkamp, D.G.; Bosch, M.A. van den; Algra, A.; Graaf, Y. van der; Rosendaal, F.R.
In:	Journal of Thrombosis and Haemostasis, 2, 35 - 41. ISSN 1538-7933.

Abstract:

In young women data are limited about the association between myocardial infarction (MI) and hyperhomocysteinemia, low folate or methylenetetrahydrofolate reductase (MTHFR) genotypes. The effect of oral contraceptive (OC) use on plasma homocysteine levels is not clear. We assessed the association be

Endothelium-derived hyperpolarizing factor-mediated renal vasodilatory response is impaired during acute and chronic hyperhomocysteinemia. (2004)

Authors: Vriese, A.S. de; Blom, H.J.; Heil, S.G.; Mortier, S.; Kluijtmans, L.A.J.; Voorde, J. van de; Lameire, N.H.
In: Circulation, 109, 2331 - 2336. ISSN 0009-7322.

Abstract:
BACKGROUND: Endothelial dysfunction is an early event in the development of vascular complications in hyperhomocysteinemia. Endothelial cells release a number of vasodilators, including NO and prostacyclin. Several lines of evidence have indicated the existence of a third vasodilator pathway, mediat
The 894 G > T variant of endothelial nitric oxide synthase (eNOS) increases the risk of recurrent venous thrombosis through interaction with elevated homocysteine levels. (2004)

Authors: Heil, S.G.; Heijer, M. den; Rijt-Pisa, B.J.M. van der; Kluijtmans, L.A.J.; Blom, H.J.
In: Journal of Thrombosis and Haemostasis, 2, 750 - 753. ISSN 1538-7933.

Abstract:
BACKGROUND: Venous thrombosis is a multicausal disease involving both genetic as well as acquired risk factors. Hyperhomocysteinemia is associated with a 2-fold increased risk of recurrent venous thrombosis (RVT). Recently, the 894 G > T variant of endothelial nitric oxide synthase (eNOS) was pos

Authors:	Vriese, A.S. de; Blom, H.J.; Heil, S.G.; Mortier, S.; Kluijtmans, L.A.J.; Voorde, J. van de; Lameire, N.H.
In:	Circulation, 109, 2331 - 2336. ISSN 0009-7322.

Authors:	Heil, S.G.; Heijer, M. den; Rijt-Pisa, B.J.M. van der; Kluijtmans, L.A.J.; Blom, H.J.
In:	Journal of Thrombosis and Haemostasis, 2, 750 - 753. ISSN 1538-7933.

[From gene to disease: cystinosis] (2004)

Authors:	Levtchenko, E.N.; Wilmer, M.J.G.; Graaf-Hess, A.C. de; Heuvel, L.P.W.J. van den; Blom, H.J.; Monnens, L.A.H.
In:	Nederlands Tijdschrift voor Geneeskunde, 148, 476 - 478. ISSN 0028-2162.

Abstract:

Cystinosis is an autosomal recessive disorder caused by an impaired transport of cystine out of lysosomes. The most severe infantile form of cystinosis starts with Fanconi syndrome at the age of 3-6 months. Untreated patients develop renal failure before the age of 10. The cystinosis gene (CTNS) map

Thioredoxin interacting protein in Dutch families with familial combined hyperlipidemia. (2004)

Authors: Hijmans, A.G.M.; Kluijtmans, L.A.J.; Blom, H.J.; Stalenhoef, A.F.H.; Graaf, J. de
In: American Journal of Medical Genetics Part A, 130, 73 - 75. ISSN 1552-4825.

Abstract:
Familial combined hyperlipidemia (FCH), characterized by multiple lipoprotein phenotypes, is the most common hereditary lipid disorder in humans. A mutant mouse strain, HcB-19, with similar biochemical features as FCH patients, has recently been identified. The mutation causing the FCH phenotype in
The role of hyperhomocysteinemia in nitric oxide (NO) and endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilatation (2004)

Authors: Heil, S.G.; Vriese, A.S. de; Kluijtmans, L.A.J.; Mortier, S.; Heijer, M. den; Blom, H.J.
In: Cellular and Molecular Biology, 50, 911 - 916. ISSN 0145-5680.

Authors:	Hijmans, A.G.M.; Kluijtmans, L.A.J.; Blom, H.J.; Stalenhoef, A.F.H.; Graaf, J. de
In:	American Journal of Medical Genetics Part A, 130, 73 - 75. ISSN 1552-4825.

Authors:	Heil, S.G.; Vriese, A.S. de; Kluijtmans, L.A.J.; Mortier, S.; Heijer, M. den; Blom, H.J.
In:	Cellular and Molecular Biology, 50, 911 - 916. ISSN 0145-5680.

Comparison of cystine determination in mixed leukocytes vs polymorphonuclear leukocytes for diagnosis of cystinosis and monitoring of cysteamine therapy. (2004)

Authors:	Levtchenko, E.N.; Graaf-Hess, A.C. de; Wilmer, M.J.G.; Heuvel, L.P.W.J. van den; Monnens, L.A.H.; Blom, H.J.
In:	Clinical Chemistry, 50, 1686 - 1688. ISSN 0009-9147.

Pages:

<< < 4 5 6 7 8 9 10 11 12 13 > >>