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Prof.dr. J.A.P. Heesterbeek Person

Prof.dr. J.A.P. Heesterbeek

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  • Data mining to detect clinical mastitis with automatic milking (2010)Open access

    Authors:Kamphuis, C.; Mollenhorst, H.; Heesterbeek, J.A.P.; Hogeveen, H.

    Abstract:

    Our objective was to use data mining to develop and validate a detection model for clinical mastitis (CM) using sensor data collected at nine Dutch dairy herds milking automatically. Sensor data was available for almost 3.5 million quarter milkings (QM) from 1,109 cows; 348 QM with CM were observed

  • Effect of Eimeria acervulina infection history on the immune response and transmission in broilers (2010)

    Authors:Velkers, F.C.; Swinkels, W.J.C.; Rebel, J.M.J.; Bouma, A.; Daemen, A.J.J.M.; Klinkenberg, D.; Boersma, W.J.A.; Stegeman, J.A.; Jong, de M.C.M.; Heesterbeek, J.A.P.
    In:Veterinary Parasitology, 173(3-4), 184 - 192. ISSN 0304-4017.

    Abstract:

    Heterogeneity in exposure to Eimeria spp. of chickens in a flock will result in differences between individual birds in oocyst output and acquired immunity, which subsequently affects transmission of the parasite in the population. The aim of this study was to quantify effects of previous infection

  • The ideal reporting interval for an epidemic to objectively interpret the epidemiological time course (2010)

    Authors:Nishiura, H.M.; Chowell, Gerardo; Heesterbeek, H.; Wallinga, J.
    In:Journal of the Royal Society interface, 7, 297 - 307. ISSN 1742-5689.

    Abstract:

    The reporting interval of infectious diseases is often determined as a time unit in the calendar regardless of the epidemiological characteristics of the disease. No guidelines have been proposed to choose the reporting interval of infectious diseases. The present study aims at translating coarsely

  • Methicillin resistant Staphylococcus aureus ST398 in veal calf farming: Human MRSA carriage related with animal antimicrobial usage and farm hygiene (2010)Open access

    Authors:Graveland, H.; Wagenaar, J.A.; Heesterbeek, H.; Mevius, D.J.; Duijkeren, E. van; Heederik, D.
    In:PLoS ONE [E], 5, e10990. ISSN 1932-6203.

    Abstract:

    INTRODUCTION: Recently a specific MRSA sequence type, ST398, emerged in food production animals and farmers. Risk factors for carrying MRSA ST398 in both animals and humans have not been fully evaluated. In this cross-sectional study, we investigated factors associated with MRSA colonization in veal

  • Effect of Eimeria acervulina infection history on the immune response and transmission in broilers (2010)

    Authors:Velkers, F.C.; Swinkels, W.J.C.; Rebel, J.M.J.; Bouma, A.; Daemen, A.J.J.M.; Klinkenberg, D.; Boersma, W.J.A.; Stegeman, A.; Jong, M.C.M. de; Heesterbeek, J.A.P.
    In:Veterinary Parasitology, 173, 184 - 192. ISSN 0304-4017.

    Abstract:

    Heterogeneity in exposure to Eimeria spp. of chickens in a flock will result in differences between individual birds in oocyst output and acquired immunity, which subsequently affects transmission of the parasite in the population. The aim of this study was to quantify effects of previous infection

  • The construction of next-generation matrices for compartmental epidemic models (2010)

    Authors:Diekmann, O.; Heesterbeek, J.A.P.; Roberts, M.G.
    In:Journal of the Royal Society Interface, 7, 873 - 885. ISSN 1742-5689.

    Abstract:

    The basic reproduction number R0 is arguably the most important quantity in infectious disease epidemiology. The next-generation matrix (NGM) is the natural basis for the definition and calculation of R0 where finitely many different categories of individuals are recognized. We clear up confusion th

  • Prioritizing emerging zoonoses in The Netherlands (2010)Open access

    Authors:Havelaar, A.H.; Rosse, F. van; Bucura, C.; Toetenel, M.A.; Haagsma, J.A.; Kurowicka, D.; Heesterbeek, J.A.P.; Speybroeck, N.; Langelaar, M.F.M.; Giessen, J.W.B. van der; Cooke, R.M.; Braks, M.A.H.
    In:PLoS one, 5, e13965 - e13965. ISSN 1932-6203.

    Abstract:

    To support the development of early warning and surveillance systems of emerging zoonoses, we present a general method to prioritize pathogens using a quantitative, stochastic multi-criteria model, parameterized for the Netherlands. A risk score was based on seven criteria, reflecting assessments

  • Prediction of the herd somatic cell count of the following month using a linear mixed effect model (2010)Open access

    Authors:Lievaart, J.J.; Barkema, H.W.; Broek, J. van den; Heesterbeek, J.A.P.; Kremer, W.D.J.
    In:Journal of Dairy Science, 93, 234 - 241. ISSN 0022-0302.

    Abstract:

    An accurate prediction of the average somatic cell count (SCC) for the next month would be a valuable tool to support udder health management decisions. A linear mixed effect (LME) model was used to predict the average herd SCC (HSCC) for the following month. The LME model included data on SCC, herd

  • Prioritizing Emerging Zoonoses in The Netherlands (2010)Open access

    Authors:Havelaar, A.H.; Rosse, F.; Bubura, C.; Toetenel, M.A.; Haagsma, J.A.; Kurowicka, D.; Heesterbeek, J.A.P.; Giessen, van der J.W.B.
    In:PLoS One, 5(11). ISSN 1932-6203.

    Abstract:

    Background To support the development of early warning and surveillance systems of emerging zoonoses, we present a general method to prioritize pathogens using a quantitative, stochastic multi-criteria model, parameterized for the Netherlands. Methodology/Principal Findings A risk score was based o

  • Does cardiovascular performance of modern fattening pigs obey allometric scaling laws? (2009)

    Authors:Essen, van G.J.; Vernooij, J.C.M.; Heesterbeek, J.A.P.; Anjema, D.; Merkus, D.; Duncker, D.J.
    In:Journal of Animal Science, 87(6), 1991 - 1997. ISSN 0021-8812.

    Abstract:

    In view of the remarkable decrease of the relative heart weight and the relative blood volume in growing pigs, we investigated whether cardiac output (CO) and stroke volume (SV) of modern growing pigs are proportional to body mass (M), as predicted by allometric scaling laws: CO (or SV) = a.Mb, in w

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