Dr. M.J.P. Gerritsen

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Radboud University Nijmegen (55)

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Clinical and histological effects of blue light on normal skin. (2010)

Authors:	Kleinpenning, M.M.; Smits, T.; Frunt, M.H.A.; Erp, P.E.J. van; Kerkhof, P.C.M. van de; Gerritsen, R.M.
In:	Photodermatology Photoimmunology & Photomedicine, 26, 16 - 21. ISSN 0905-4383.

Abstract:

INTRODUCTION: Phototherapy with visible light is gaining interest in dermatological practice. Theoretically, blue light could induce biological effects comparable to ultraviolet A (UVA) radiation. OBJECTIVES: To study the effects of blue light on normal skin in terms of photodamage, skin ageing and

Treatment nonadherence and long-term effects of narrowband UV-B therapy in patients with psoriasis. (2010)

Authors:	Evers, A.W.M.; Kleinpenning, M.M.; Smits, T.; Boezeman, J.B.M.; Kerkhof, P.C.M. van de; Kraaimaat, F.W.; Gerritsen, M.J.P.
In:	Archives of Dermatology, 146, 198 - 199. ISSN 0003-987x.

Fluorescence diagnosis in actinic keratosis and squamous cell carcinoma. (2010)

Authors:	Kleinpenning, M.M.; Wolberink, E.A.W.; Smits, T.; Blokx, W.A.M.; Kerkhof, P.C.M. van de; Erp, P.E.J. van; Gerritsen, M.J.P.
In:	Photodermatology Photoimmunology & Photomedicine, 26, 297 - 302. ISSN 0905-4383.

Abstract:

BACKGROUND: As different tissue types have distinct capabilities to accumulate protoporphyrin IX, fluorescence diagnosis with aminolevulinic acid-induced porphyrins (FDAP) could be used to discriminate between different types of tissue. Previous results demonstrated higher fluorescence ratios in squ

The effects of keratolytic pretreatment prior to fluorescence diagnosis and photodynamic therapy with aminolevulinic acid-induced porphyrins in psoriasis. (2010)

Authors:	Kleinpenning, M.M.; Kanis, J.H.; Smits, T.; Erp, P.E.J. van; Kerkhof, P.C.M. van de; Gerritsen, M.J.P.
In:	Journal of Dermatological Treatment, 21, 245 - 251. ISSN 0954-6634.

Abstract:

BACKGROUND: Psoriasis lesions accumulate protoporphyrin IX (PpIX) with a variable distribution within plaques due to variations in hyperkeratosis causing differences in penetration of cream or light. Objectives: To study the effects of different keratolytic pretreatments in PpIX-induced fluorescence

The clinical efficacy of topical methyl-aminolevulinate photodynamic therapy in moderate to severe actinic keratoses of the face and scalp. (2010)

Authors: Kleinpenning, M.M.; Kerkhof, P.C.M. van de; Gerritsen, M.J.P.
In: Journal of Dermatological Treatment, 21, 252 - 257. ISSN 0954-6634.

Abstract:
INTRODUCTION: Since actinic keratoses (AKs) often appear in areas with field cancerization, photodynamic therapy (PDT) may have significant advantages over the standard treatment options. Objectives: Clinical efficacy of PDT with topical methyl aminolevulinate (MAL-PDT) in field cancerization was ev

Authors:	Kleinpenning, M.M.; Kerkhof, P.C.M. van de; Gerritsen, M.J.P.
In:	Journal of Dermatological Treatment, 21, 252 - 257. ISSN 0954-6634.

Regionale metastasen van plaveiselcelcarcinoom van de huid in het hoofd-halsgebied (2009)

Authors:	Heer, A.R de; Bouman, H.J.; Gerritsen, M.J.P.; Ingels, K.J.A.O.; Kaanders, J.H.A.M.; Takes, R.P.
In:	Nederlands Tijdschrift voor Geneeskunde, 152, 2645 - 2649. ISSN 0028-2162.

Itch and scratching as predictors of time to clearance of psoriasis with narrow-band ultraviolet B therapy. (2009)

Authors:	Evers, A.W.M.; Kleinpenning, M.M.; Smits, T.; Boezeman, J.B.M.; Kerkhof, P.C.M. van de; Kraaimaat, F.W.; Gerritsen, M.J.P.
In:	British Journal of Dermatology, 161, 542 - 546. ISSN 0007-0963.

Abstract:

BACKGROUND: Narrow-band ultraviolet (UV) B phototherapy is an effective treatment for psoriasis. However, there is considerable variability in the number of treatment sessions needed to achieve psoriasis clearance. While several clinical and treatment-related factors predict time to clearance, the e

Induction of protoporphyrin IX by aminolaevulinic acid in actinic keratosis, psoriasis and normal skin: preferential porphyrin enrichment in differentiated cells. (2009)

Authors:	Smits, T.; Laarhoven, A.I.M. van; Staassen, A.; Kerkhof, P.C.M. van de; Erp, P.E.J. van; Gerritsen, M.J.P.
In:	British Journal of Dermatology, 160, 849 - 857. ISSN 0007-0963.

Abstract:

BACKGROUND: In photodynamic therapy the endogenous photosensitizer protoporphyrin IX (PpIX) is synthesized following topical application of aminolaevulinic acid (ALA). However, different tissues have distinct PpIX-accumulating properties, due to differences in penetration of ALA through the stratum

In situ expression of tumor antigens by messenger RNA-electroporated dendritic cells in lymph nodes of melanoma patients. (2009)

Authors:	Schuurhuis, D.H.; Verdijk, P.; Schreibelt, G.; Aarntzen, E.H.J.G.; Scharenborg, N.M.; Boer, A.J. de; Rakt, M.W.M.M. van de; Kerkhoff, M.M.A.; Gerritsen, M.J.P.; Eijckeler, F.D.J.; Bonenkamp, J.J.; Blokx, W.A.M.; Krieken, J.H.J.M. van; Boerman, O.C.; Oyen, W.J.G.; Punt, C.J.A.; Figdor, C.G.; Adema, G.J.; Vries, I.J.M. de
In:	Cancer Research, 69, 2927 - 2934. ISSN 0008-5472.

Abstract:

Electroporation of dendritic cells (DC) with mRNA encoding tumor-associated antigens (TAA) for cancer immunotherapy has been proved efficient and clinically safe. It obviates prior knowledge of CTL and Th epitopes in the antigen and leads to the presentation of multiple epitopes for several HLA alle

Narrowband ultraviolet B therapy in psoriasis: randomized double-blind comparison of high-dose and low-dose irradiation regimens. (2009)

Authors:	Kleinpenning, M.M.; Smits, T.; Boezeman, J.B.M.; Kerkhof, P.C.M. van de; Evers, A.W.M.; Gerritsen, M.J.P.
In:	British Journal of Dermatology, 161, 1351 - 1356. ISSN 0007-0963.

Abstract:

BACKGROUND: Ultraviolet (UV) B phototherapy is an established treatment option for psoriasis. The optimum dosage regimen still has to be determined. Within-subject comparisons do not take into account the systemic effects of UVB phototherapy. The area of the body treated with low-dose UVB may benefi

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