KNAW

Back to search results
Person

Prof.dr. R.J. Bino

Pagina-navigatie:
filter results
Type
Date
Accessibility
Institution

11-20 out of 41 results by:date

Save search results

  • Carotenoid and Fatty Acid Metabolism in Light-Stressed Dunaliella salina (2010)

    Authors:Lamers, P.P.; Laak, C.W.; Kaasenbrood, P.S.; Lorier, J.; Janssen, M.G.J.; Vos, de C.H.; Bino, R.J.; Wijffels, R.H.
    In:Biotechnology and Bioengineering, 106(4), 638 - 648. ISSN 0006-3592.

    Abstract:

    Carotene is overproduced in the alga Dunaliella salina in response to high light intensities. We have studied the effects of a sudden light increase on carotenoid and fatty acid metabolism using a flat panel photobioreactor that was run in turbidostat mode to ensure a constant light regime througho

  • Susceptibility of the Tomato Mutant High Pigment-2dg (hp-2dg) to Orobanche spp. Infection (2008)

    Authors:Lopez Raez, J.A.; Charnikhova, T.; Mulder, P.P.J.; Kohlen, W.; Bino, R.J.; Levin, I.; Bouwmeester, H.J.
    In:Journal of Agricultural and Food Chemistry, 56(15), 6326 - 6332. ISSN 0021-8561.

    Abstract:

    The consumption of natural products with potential health benefits has been continuously growing, and enhanced pigmentation is of major economic importance in fruits and vegetables. The tomato hp-2dg is an important mutant line that has been introgressed into commercial tomato cultivars marketed as

  • Intra- and inter-metabolite correlation spectroscopy of tomato metabolomics data obtained by liquid chromatography-mass spectrometry and nuclear magnetic resonance (2008)Open access

    Authors:Moco, S.I.A.; Forshed, J.; Vos, de C.H.; Bino, R.J.; Vervoort, J.J.M.
    In:Metabolomics, 4(3), 202 - 215. ISSN 1573-3882.

    Abstract:

    Nuclear magnetic resonance (NMR) and liquid chromatography-mass spectrometry (LCMS) are frequently used as technological platforms for metabolomics applications. In this study, the metabolic profiles of ripe fruits from 50 different tomato cultivars, including beef, cherry and round types, were reco

  • Exploring and exploiting carotenoid accumulation in Dunaliella salina for cell-factory applications (2008)

    Authors:Lamers, P.P.; Janssen, M.G.J.; Vos, de C.H.; Bino, R.J.; Wijffels, R.H.
    In:Trends in Biotechnology, 26(11), 631 - 638. ISSN 0167-7799.

    Abstract:

    The unicellular alga Dunaliella salina is the most interesting cell factory for the commercial production of ß-carotene because this species accumulates carotenoids to high concentrations. Nevertheless, little is known about the underlying mechanisms of carotenoid accumulation. Here, we review the r

  • The role of oxidative stress in the differential effects between n - 3 and n - 6 polyunsaturated fatty acids and the protective effects of algal and fish oil in colon carcinogenesis (2007)

    Authors:Alink, G.M.; Beelen, van V.A.; Aarts, J.M.M.J.G.; Bino, R.J.; Bosch, H.J.; Hooiveld, G.J.E.J.; Mooibroek, H.; Muller, M.R.; Reus, A.; Roeleveld, J.; Sijtsma, L.; Spenkelink, A.; Rietjens, I.M.C.M.

  • Iridoids from Pentas lanceolata (Forssk.) Deflers (2007)

    Authors:Schripsema, J.; Caprini, C.P.; Heijden, van der R.; Bino, R.J.; Vos, de C.H.; Dagnino, D.
    In:Journal of Natural Products, 70(9), 1495 - 1498. ISSN 0163-3864.

    Abstract:

    From the aerial parts of Pentas lanceolata, belonging to the family Rubiaceae, a series of iridoid glucosides was isolated by preparative HPLC. Seven iridoid glucosides were identified. Besides asperuloside and asperulosidic acid, characteristic iridoids for Rubiaceae, five new iridoids were isolate

  • Metabolomics technologies and metabolite identification (2007)

    Authors:Moco, S.I.A.; Bino, R.J.; Vos, de C.H.; Vervoort, J.J.M.
    In:TrAC : Trends in Analytical Chemistry, 26(9), 855 - 866. ISSN 0165-9936.

    Abstract:

    Metabolomics studies rely on the analysis of the multitude of small molecules (metabolites) present in a biological system. Most commonly, metabolomics is heavily supported by mass spectrometry (MS) and nuclear magnetic resonance (NMR) as parallel technologies that provide an overview of the metabol

  • A comparative study on the effect of algal and fish oil on viability and cell proliferation of Caco-2 cells (2007)

    Authors:Beelen, van V.A.; Roeleveld, J.; Mooibroek, H.; Sijtsma, L.; Bino, R.J.; Bosch, H.J.; Rietjens, I.M.C.M.; Alink, G.M.
    In:Food and Chemical Toxicology, 45(5), 716 - 724. ISSN 0278-6915.

    Abstract:

    Polyunsaturated fatty acid (PUFA) rich micro-algal oil was tested in vitro and compared with fish oil for antiproliferative properties on cancer cells in vitro. Oils derived from Crypthecodinium cohnii, Schizochytrium sp. and Nitzschia laevis, three commercial algal oil capsules, and menhaden fish o

  • Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometry (2007)

    Authors:Vos, de C.H.; Moco, S.I.A.; Lommen, A.; Keurentjes, J.J.B.; Bino, R.J.; Hall, R.D.
    In:Nature protocols, 2(4), 778 - 791. ISSN 1754-2189.

    Abstract:

    Untargeted metabolomics aims to gather information on as many metabolites as possible in biological systems by taking into account all information present in the data sets. Here we describe a detailed protocol for large-scale untargeted metabolomics of plant tissues, based on reversed phase liquid c

  • Tissue specialization at the metabolite level is perceived during the development of tomota fruit. (2007)

    Authors:Moco, S.I.A.; Capanoglu, E.; Tikunov, Y.M.; Bino, R.J.; Boyacioglu, D.; Hall, R.D.; Vervoort, J.J.M.; Vos, de C.H.
    In:Journal of Experimental Botany, 58(15-16), 4131 - 4146. ISSN 0022-0957.

    Abstract:

    Fruit maturation and tissue differentiation are important topics in plant physiology. These biological phenomena are accompanied by specific alterations in the biological system, such as differences in the type and concentration of metabolites. The secondary metabolism of tomato (Solanum lycopersicu

Pages:

 < 1 2 3 4 5 > 

Go to page top
Go back to contents
Go back to site navigation