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Prof.dr. F.C.P. Holstege

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Article (2)

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Utrecht University (2)

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Tight control of MEK-ERK activation is essential in regulating proliferation, survival, and cytokine production of CD34+-derived neutrophil progenitors (2009)

Authors: Geest, C.R.; Buitenhuis, M.; Groot Koerkamp, M.J.A.; Holstege, F.C.P.; Vellenga, E.; Coffer, P.J.
In: Blood, 114, 3402 - 3412. ISSN 0006-4971.

Abstract:
A plethora of extracellular stimuli regulate growth, survival, and differentiation responses through activation of the MEKERK MAPK signaling module. Using CD34 hematopoietic progenitor cells, we describe a novel role for the MEK-ERK signaling module in the regulation of proliferation, survival, and

Nitric oxide donor induces temporal and doce-dependent reduction of gene expression in human endothelial cells (2004)Open access

Authors:	Braam, G.B.; Roos, R. de; Dijk, A.; Boer, P.; Post, J.A.; Kemmeren, P.P.C.W.; Holstege, F.C.P.; Bluijssen, J.A.R.; Koomans, H.A.
In:	American Journal of Physiology-Heart and Circulatory Physiology, 287, H1977 - H1986. ISSN 0363-6135.

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