Dr. P.E.J. van Erp

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Radboud University Nijmegen (57)

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Clinical and histological effects of blue light on normal skin. (2010)

Authors:	Kleinpenning, M.M.; Smits, T.; Frunt, M.H.A.; Erp, P.E.J. van; Kerkhof, P.C.M. van de; Gerritsen, R.M.
In:	Photodermatology Photoimmunology & Photomedicine, 26, 16 - 21. ISSN 0905-4383.

Abstract:

INTRODUCTION: Phototherapy with visible light is gaining interest in dermatological practice. Theoretically, blue light could induce biological effects comparable to ultraviolet A (UVA) radiation. OBJECTIVES: To study the effects of blue light on normal skin in terms of photodamage, skin ageing and

Treatment of plaque psoriasis with the two-compound product calcipotriol/betamethasone dipropionate versus both monotherapies: An immunohistochemical study. (2010)

Authors:	Velden, H.M.J. van der; Pasch, M.C.; Erp, P.E.J. van; Lingen, R.G. van; Kooijmans-Otero, M.E.; Boer-van Huizen, R.T. de; Kerkhof, P.C.M. van de
In:	Journal of Dermatological Treatment, 21, 13 - 22. ISSN 0954-6634.

Abstract:

The combination of calcipotriol (Cp) and topical corticosteroids increases efficacy and reduces side effects as compared to monotherapies. Previous studies suggest that such combinations may have an added value with respect to reduction of T-cell subsets. A two-compound product consisting of Cp and

Fluorescence diagnosis in actinic keratosis and squamous cell carcinoma. (2010)

Authors:	Kleinpenning, M.M.; Wolberink, E.A.W.; Smits, T.; Blokx, W.A.M.; Kerkhof, P.C.M. van de; Erp, P.E.J. van; Gerritsen, M.J.P.
In:	Photodermatology Photoimmunology & Photomedicine, 26, 297 - 302. ISSN 0905-4383.

Abstract:

BACKGROUND: As different tissue types have distinct capabilities to accumulate protoporphyrin IX, fluorescence diagnosis with aminolevulinic acid-induced porphyrins (FDAP) could be used to discriminate between different types of tissue. Previous results demonstrated higher fluorescence ratios in squ

The effects of keratolytic pretreatment prior to fluorescence diagnosis and photodynamic therapy with aminolevulinic acid-induced porphyrins in psoriasis. (2010)

Authors:	Kleinpenning, M.M.; Kanis, J.H.; Smits, T.; Erp, P.E.J. van; Kerkhof, P.C.M. van de; Gerritsen, M.J.P.
In:	Journal of Dermatological Treatment, 21, 245 - 251. ISSN 0954-6634.

Abstract:

BACKGROUND: Psoriasis lesions accumulate protoporphyrin IX (PpIX) with a variable distribution within plaques due to variations in hyperkeratosis causing differences in penetration of cream or light. Objectives: To study the effects of different keratolytic pretreatments in PpIX-induced fluorescence

Molecular diagnostics of psoriasis, atopic dermatitis, allergic contact dermatitis and irritant contact dermatitis. (2010)

Authors:	Kamsteeg, M.; Jansen, P.A.M.; Vlijmen-Willems, I.M.J.J. van; Erp, P.E.J. van; Rodijk-Olthuis, D.; Valk, P.G.M. van der; Feuth, T.; Zeeuwen, P.L.J.M.; Schalkwijk, J.
In:	British Journal of Dermatology, 162, 568 - 578. ISSN 0007-0963.

Abstract:

BACKGROUND: Microarray studies on the epidermal transcriptome in psoriasis and atopic dermatitis (AD) have revealed genes with disease-specific expression in keratinocytes of lesional epidermis. These genes are possible candidates for disease-specific pathogenetic changes, but could also provide a t

Persistent expression of CD26/DPPIV after treatment with infliximab in psoriasis despite clinical improvement (2009)

Authors:	Lingen, R.G. van; Erp, P.E.J. van; Seyger, M.M.B.; Jong, E.M.G.J. de; Boer-van Huizen, R.T. de; Driessen, R.J.B.; Kerkhof, P.C.M. van de
In:	Acta Dermato-Venereologica, 89, 518 - 520. ISSN 0001-5555.

Induction of protoporphyrin IX by aminolaevulinic acid in actinic keratosis, psoriasis and normal skin: preferential porphyrin enrichment in differentiated cells. (2009)

Authors:	Smits, T.; Laarhoven, A.I.M. van; Staassen, A.; Kerkhof, P.C.M. van de; Erp, P.E.J. van; Gerritsen, M.J.P.
In:	British Journal of Dermatology, 160, 849 - 857. ISSN 0007-0963.

Abstract:

BACKGROUND: In photodynamic therapy the endogenous photosensitizer protoporphyrin IX (PpIX) is synthesized following topical application of aminolaevulinic acid (ALA). However, different tissues have distinct PpIX-accumulating properties, due to differences in penetration of ALA through the stratum

Good clinical response to anti-psoriatic treatment with adalimumab and methotrexate does not inflict a direct effect on compartmentalization of T-cell subsets: a pilot study. (2009)

Authors:	Lingen, R.G. van; Jong, E.M.G.J. de; Berends, M.A.M.; Seijger, M.M.B.; Erp, P.E.J. van; Kerkhof, P.C.M. van de
In:	Journal of Dermatological Treatment, 19, 284 - 287. ISSN 0954-6634.

Treatment of plaque psoriasis with the two-compound product calipotriol/betamethasone dipropionate versus both monotherapies: An imunnohistochemical study. (2009)

Authors:	Velden, S.J.M. van der; Pasch, M.C.; Erp, P.E.J. van; Lingen, R.G. van; Kooijmans-Otero, M.E.; Boer, R.T. de; Kerkhof, P.C.M. van de
In:	Journal of Dermatological Treatment, 61, 1626 - 1632. ISSN 0954-6634.

The universal detection of antigens from one skin biopsy specimen. (2009)

Authors:	Velden, H.M.J. van der; Kerkhof, P.C.M. van de; Pasch, M.C.; Boer-van Huizen, R.T. de; Lingen, R.G. van; Erp, P.E.J. van
In:	Journal of Cutaneous Pathology, 36, 972 - 979. ISSN 0303-6987.

Abstract:

BACKGROUND: Immunohistochemistry is an important tool in dermatology but is limited. Certain antigens can only be preserved in formalin-fixed paraffin-embedded sections, while others can only be detected on frozen sections, resulting in situations where two biopsies are needed. We aimed to develop a

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