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Dr. P.J.F.M. Merkus

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  • Comparing Global Initiative for Asthma (GINA) criteria with the Childhood Asthma Control Test (C-ACT) and Asthma Control Test (ACT) (2011)

    Authors:Koolen, B.B.; Pijnenburg, M.W.; Brackel, H.J.; Landstra, A.M.; Berg, N.J. van den; Merkus, P.J.F.M.; Hop, W.C.J.; Vaessen-Verberne, A.A.
    In:European Respiratory Journal, 38, 561 - 566. ISSN 0903-1936.

    Abstract:

    Several tools are useful in detecting uncontrolled asthma in children. The aim of this study was to compare Global Initiative for Asthma (GINA) guidelines with the Childhood Asthma Control Test (C-ACT) and the Asthma Control Test (ACT) in detecting uncontrolled asthma in children. 145 children with

  • Extravascular lung water index and global end-diastolic volume index should be corrected in children (2011)

    Authors:Lemson, J.; Merkus, P.J.F.M.; Hoeven, J.G. van der
    In:Journal of Critical Care, 26, 432 e7 - 432 12. ISSN 0883-9441.

    Abstract:

    PURPOSE: The aim of the present study was to explain why extravascular lung water index (EVLWI) is higher and why global end-diastolic blood volume index (GEDVI) is lower in young children when measured with the PiCCO system (Pulsion, Munich, Germany). MATERIALS AND METHODS: We pooled available data

  • Prospective longitudinal evaluation of lung function during the first year of life after extracorporeal membrane oxygenation (2011)

    Authors:Hofhuis, W.; Hanekamp, M.N.; Ijsselstijn, H.; Nieuwhof, E.M.; Hop, W.C.J.; Tibboel, D.; Jongste, J.C. de; Merkus, P.J.F.M.
    In:Pediatric Critical Care Medicine, 12, 159 - 164. ISSN 1529-7535.

    Abstract:

    OBJECTIVE: To collect longitudinal data on lung function in the first year of life after extracorporeal membrane oxygenation and to evaluate relationships between lung function and perinatal factors. Longitudinal data on lung function in the first year of life after extracorporeal membrane oxygenati

  • Validation of a web-based version of the asthma control test and childhood asthma control test (2011)

    Authors:Koolen, B.B.; Pijnenburg, M.W.; Brackel, H.J.; Landstra, A.M.; Berg, N.J. van den; Merkus, P.J.F.M.; Hop, W.C.J.; Vaessen-Verberne, A.A.
    In:Pediatric Pulmonology, 46, 941 - 948. ISSN 8755-6863.

    Abstract:

    RATIONALE: Recent guidelines focus on adjusting asthma treatment to the level of asthma control. The availability of a web-based asthma control questionnaire offers the possibility to assess asthma control without the need of outpatient clinic visits. The aim of this study was to evaluate the agreem

  • Psychological characteristics associated with the onset and course of asthma in children and adolescents: a systematic review of longitudinal effects (2011)

    Authors:Tibosch, M.M.; Verhaak, C.M.; Merkus, P.J.F.M.
    In:Patient Education and Counseling, 82, 11 - 19. ISSN 0738-3991.

    Abstract:

    OBJECTIVE: to systematically review all available studies that investigated the longitudinal relationships between the psychological characteristics of children and adolescents suffering from asthma and those of their caregivers, and the onset and course of the asthma. METHODS: relevant studies were

  • How about your peers? Cystic fibrosis questionnaire data from healthy children and adolescents (2011)Open access

    Authors:Tibosch, M.M.; Sintnicolaas, C.J.; Peters, J.B.; Merkus, P.J.F.M.; Yntema, J.L.; Verhaak, C.M.; Vercoulen, J.H.M.M.
    In:BMC Pediatrics, 11, 86 - 86. ISSN 1471-2431.

    Abstract:

    BACKGROUND: The Cystic Fibrosis Questionnaire (CFQ) is widely used in research as an instrument to measure quality of life in patients with cystic fibrosis (CF). In routine patient care however, measuring quality of life is still not implemented in guidelines. One of the reasons might be the lack of

  • Respiratory medicines for children: Current evidence, unlicensed use and research priorities (2010)

    Authors:Smyth, A.R.; Barbato, A. (A.); Beydon, N. (Nicole); Bisgaard, H.; Boeck, de K.; Brand, P.L.P. (Paul L.P.); Bush, A.; Fauroux, B. (Brigitte); Jongste, de J.C. (Johan); Korppi, M.; O'Callaghan, C.; Pijnenburg, M.W.H. (Mariëlle); Ratjen, F. (Felix); Southern, K.; Spencer, D.; Thomson, A.; Vyas, H.; Warris, A. (Adilia); Merkus, P.J.F.M. (Peter)
    In:The European Respiratory Journal, 35(2), 247 - 265. ISSN 0903-1936.

    Abstract:

    This European Respiratory Society task force has reviewed the evidence for paediatric medicines in respiratory disease occurring in adults and children. We describe off-licence use, research priorities and ongoing studies. Off-licence and off-label prescribing in children is widespread and potential

  • An asthma-related quality of life instrument is unable to identify asthmatic children with major psychosocial problems. (2010)

    Authors:Tibosch, M.M.; Reidsma, C.; Landstra, A.; Hugen, C.A.C.; Gerrits, P.; Brouwer, M.; Gent, R. van; Merkus, P.J.F.M.; Verhaak, C.M.
    In:European Journal of Pediatrics, 169, 1495 - 1501. ISSN 0340-6199.

    Abstract:

    Evidence shows that psychosocial problems among children and adolescents with asthma interfere with adherence to treatment and therefore need attention in asthma care. It is unknown whether the already frequently implemented asthma-related quality of life (QoL) instruments reflect psychosocial probl

  • Effect of enzyme therapy in juvenile patients with Pompe disease: a three-year open-label study. (2010)

    Authors:Capelle, C.I. van; Beek, N.A. van der; Hagemans, M.L.; Arts, W.F.M.; Hop, W.C.J.; Lee, P.; Jaeken, J.; Frohn-Mulder, I.M.; Merkus, P.J.F.M.; Corzo, D.; Puga, A.C.; Reuser, A.J.J.; Ploeg, A.T. van der
    In:Neuromuscular Disorders, 20, 775 - 782. ISSN 0960-8966.

    Abstract:

    Pompe disease is a rare neuromuscular disorder caused by deficiency of acid alpha-glucosidase. Treatment with recombinant human alpha-glucosidase recently received marketing approval based on prolonged survival of affected infants. The current open-label study was performed to evaluate the response

  • Respiratory medicines for children: current evidence, unlicensed use and research priorities. (2010)

    Authors:Smyth, A.R.; Barbato, A.; Beydon, N.; Bisgaard, H.; Boeck, K. de; Brand, P.; Bush, A.; Fauroux, B.; Jongste, J. de; Korppi, M.; O'Callaghan, C.; Pijnenburg, M.A.M.; Ratjen, F.; Southern, K.; Spencer, D.; Thomson, A.; Vyas, H.; Warris, A.; Merkus, P.J.F.M.
    In:European Respiratory Journal, 35, 247 - 265. ISSN 0903-1936.

    Abstract:

    This European Respiratory Society task force has reviewed the evidence for paediatric medicines in respiratory disease occurring in adults and children. We describe off-licence use, research priorities and ongoing studies. Off-licence and off-label prescribing in children is widespread and potential

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