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Prof.dr. M.L. Simoons Person

Prof.dr. M.L. Simoons

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  • Changes in clinical profile, treatment, and mortality in patients hospitalised for acute myocardial infarction between 1985 and 2008 (2011)Open access

    Authors:Nauta, S.T. (Sjoerd); Deckers, J.W. (Jaap); Akkerhuis, K.M. (Martijn); Lenzen, M.J. (Mattie); Simoons, M.L. (Maarten); Domburg, van R.T. (Ron)
    In:PLoS ONE, 6(11). ISSN 1932-6203.

    Abstract:

    Objectives: To quantify the impact of the implementation of treatment modalities into clinical practice since 1985, on outcome of patients with ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI). Methods: All consecutive patients admitted fo

  • Encouraging survival rates in patients with acute myocardial infarction treated with an intra-aortic balloon pump (2011)Open access

    Authors:Valk, S.D.A. (Suzanne); Cheng, J.M. (Jin Ming); Uil, den C.A. (Corstiaan); Lagrand, W.K. (Wim); Ent, van der M. (Martin); Sande, van de M. (Meike); Domburg, van R.T. (Ron); Simoons, M.L. (Maarten)
    In:Netherlands Heart Journal, 19(3), 112 - 118. ISSN 1568-5888.

    Abstract:

    Objective To evaluate a 30-day and long-term outcome of patients with acute myocardial infarction (AMI) treated with intra-aortic balloon pump (IABP) counterpulsation and to identify predictors of a 30-day and long-term all-cause mortality. Methods Retrospective cohort study of 437 consecutive AMI p

  • The role of insulin therapy and glucose normalization in patients with acute coronary syndrome (2011)Open access

    Authors:Lipton, J.A.; Can, A.; Akoudad, S. (Saloua); Simoons, M.L. (Maarten)
    In:Netherlands Heart Journal, 19(2), 79 - 84. ISSN 1568-5888.

    Abstract:

    Patients with acute myocardial infarction (AMI) and diabetes mellitus, as well as patients admitted with elevated blood glucose without known diabetes, have impaired outcome. Therefore intensive glucose-lowering therapy with insulin (IGL) has been proposed in diabetic or hyperglycaemic patients and

  • Genezen is beter dan voorkomen (2010)Open access

    Author:Simoons, M.L. (Maarten)

    Abstract:

    In de tweede helft van de vorige eeuw waren hart en vaatziekten de belangrijkste doodsoorzaak in Nederland. Dit is lang zo gebleven, maar na een piek rond 1970 is de sterfte aan hart en vaatziekten, gecorrigeerd voor de leeftijd, gedaald en sinds enkele jaren staan hart en vaatziekten op de tweede p

  • Genetic determinants of treatment benefit of the angiotensin-converting enzyme-inhibitor perindopril in patients with stable coronary artery disease (2010)Open access

    Authors:Brugts, J.J. (Jasper); Isaacs, A.J. (Aaron); Boersma, E. (Eric); Duijn, van C.M. (Cock); Uitterlinden, A.G. (André); Remme, W.J. (Willem); Bertrand, M.E. (Michel); Ninomiya, T. (T.); Ceconi, C. (Claudio); Chalmers, J. (John); MacmMahon, S. (Stephen); Fox, K.M. (Kim); Ferrari, R. (Roberto); Witteman, J.C.M. (Jacqueline); Danser, A.H.J. (Jan); Simoons, M.L. (Maarten); Maat, de M.P.M. (Moniek)
    In:European Heart Journal, 31(15), 1854 - 1864. ISSN 0195-668x.

    Abstract:

    Aims The efficacy of angiotensin-converting enzyme (ACE)-inhibitors in stable coronary artery disease (CAD) may be increased by targeting the therapy to those patients most likely to benefit. However, these patients cannot be identified by clinical characteristics. We developed a genetic profile to

  • Incidence, pathophysiology, and treatment of complications during dobutamine-atropine stress echocardiography (2010)

    Authors:Geleijnse, M.L. (Marcel); Krenning, B.J. (Boudewijn); Nemes, A. (Attila); Dalen, van B.M. (Bas); Soliman, O.I.I. (Osama Ibrahim Ibrahim); Cate, ten F.J. (Folkert); Schinkel, A.F. (Arend); Boersma, H. (Eric); Simoons, M.L. (Maarten)
    In:Circulation (Baltimore), 121(15), 1756 - 1767. ISSN 0009-7322.

  • Chronic stable coronary artery disease: Drugs vs. revascularization (2010)

    Authors:Simoons, M.L. (Maarten); Windecker, S. (Stephan)
    In:European Heart Journal, 31(5), 530 - 541. ISSN 0195-668x.

    Abstract:

    Coronary artery disease remains the leading cause of mortality in most industrialized countries, although age-standardized mortality related to coronary artery disease (CAD) has decreased by more than 40 during the last two decades. Coronary atherosclerosis may cause angina pectoris, myocardial infa

  • Effects of platelet glycoprotein IIb/IIIa receptor blockers in non-ST segment elevation acute coronary syndromes: benefit and harm in different age subgroups (2008)Open access

    Authors:Hernández, A.V. (Adrián); Westerhout, C.M. (Cynthia); Steyerberg, E.W. (Ewout); Bueno, H. (Hector); White, H.D. (Harvey); Théroux, P. (Pierre); Moliterno, D.J. (David); Armstrong, P.W. (Paul); Califf, R.M. (Robert); Wallentin, L.C. (Lars); Simoons, M.L. (Maarten); Boersma, H. (Eric)
    In:Heart, 93(4), 450 - 455. ISSN 1355-6037.

    Abstract:

    Objective: To investigate whether the beneficial and harmful effects of platelet glycoprotein IIb/IIIa receptor blockers in non-ST elevation acute coronary syndromes (NSTE-ACS) depend on age. Methods: A meta-analysis of six trials of platelet glycoprotein IIb/IIIa receptor blockers in patients with

  • Rapid and accurate measurement of LV mass by biplane real-time 3D echocardiography in patients with concentric LV hypertrophy: Comparison to CMR (2008)

    Authors:Yap, S-C. (Sing-Chien); Geuns, van R-J.M. (Robert-Jan); Nemes, A. (Attila); Meijboom, F.J. (Folkert); McGhie, J. (Jackie); Geleijnse, M.L. (Marcel); Simoons, M.L. (Maarten); Roos-Hesselink, J.W. (Jolien)
    In:European Journal of Echocardiography, 9(2), 255 - 260. ISSN 1525-2167.

    Abstract:

    Aims: To evaluate the accuracy of real-time three-dimensional echocardiography (RT3DE) using a biplane and multiplane method in determining left ventricular (LV) mass compared to cardiac magnetic resonance imaging (CMR). Methods and results: LV mass was measured in 18 adult patients with congenital

  • Variation between hospitals in patient outcome after stroke is only partly explained by differences in quality of care. Data from the Netherlands Stroke Survey (2008)Open access

    Authors:Lingsma, H.F. (Hester); Dippel, D.W.J. (Diederik); Hoeks, S.E. (Sanne); Steyerberg, E.W. (Ewout); Simoons, M.L. (Maarten); Scholte op Reimer, W.J.M. (Wilma)
    In:Journal of Neurology, Neurosurgery and Psychiatry: an international peer-reviewed journal for health professionals and researchers in all areas of neurology and neurosurgery, 79(8), 888 - 894. ISSN 0022-3050.

    Abstract:

    Background and purpose:Patient outcome is often used as an indicator of quality of hospital care. The aim of this study is to investigate whether there is a straightforward relationship between quality of care and outcome and whether outcome measures could be used to assess quality of care after str

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