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Prof.dr. F.C. Verhulst

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  • Stressgevoeligheid als onderliggend mechanisme voor angstproblemen? Bevindingen uit de TRAILS-studie (2009)

    Auteurs:Greaves-Lord, K.; Verhulst, F.C.; Oldehinkel, A.J.; Ormel, J.; Huizink, A.C.
    In:Tijdschrift voor Psychiatrie_, 51, 401 - 406. ISSN 0303-7339.

    Samenvatting:

    This short report provides an overview of the results of a recent Dutch study on the relation between anxiety and the reactivity of two important stress response systems: the autonomic nervous system and the hypothalamic-pituitary-adrenal axis. Future research will have to investigate the reactivity

  • Maternal Symptoms of Anxiety During Pregnancy Affect Infant Neuromotor Development: The Generation R Study (2009)

    Auteurs:Batenburg-Eddes, T. van; Groot, L. de; Huizink, A.C.; Steegers, E.A.P.; Hofman, A.; Jaddoe, V.W.V.; Verhulst, F.C.; Tiemeier, H.
    In:Developmental Neuropsychology, 34, 476 - 493. ISSN 8756-5641.

    Samenvatting:

    Several studies found that maternal symptoms of anxiety or depression are related to functioning and development of the offspring. Within a population-based study of 2,724 children, we investigated the effect of maternal anxiety or depression on infant neuromotor development. Symptoms of anxiety and

  • High activity of monoamine oxidase A is associated with externalizing behaviour in maltreated and nonmaltreated adoptees. (2009)

    Auteurs:Vegt, E.J. van der; Oostra, B.A.; Arias Vasquez, A.; Ende, J.J. van den; Verhulst, F.C.; Tiemeier, H.
    In:Psychiatric Genetics, 19, 209 - 211. ISSN 0955-8829.

    Samenvatting:

    Individual differences in a functional polymorphism of the promoter of the Monoamine oxidase A (MAO-A) gene might partly explain the increased vulnerability of maltreated children for externalizing behaviour. A sample of 239 internationally adopted boys was studied. Adoptive parents provided the inf

  • Externalizing behaviors in preadolescents: familial risk to externalizing behaviors, prenatal and perinatal risks, and their interactions. (2009)

    Auteurs:Buschgens, C.J.M.; Swinkels, S.H.N.; Aken, M.A. van; Ormel, J.; Verhulst, F.C.; Buitelaar, J.K.
    In:European Child & Adolescent Psychiatry, 18, 65 - 74. ISSN 1018-8827.

    Samenvatting:

    BACKGROUND: Accumulating evidence indicates that there is a rich and varied interplay between persons and their environments, which strongly suggests that this involves gene-environment correlations and interactions. We investigated whether familial risk (FR) to externalizing behaviors and prenatal

  • Suggestive linkage of ADHD to chromosome 18q22 in a young genetically isolated Dutch population. (2009)

    Auteurs:Amin, N.; Aulchenko, Y.S.; Dekker, M.C.J.; Ferdinand, R.F.; Spreeken, A. van; Temmink, A.H.; Verhulst, F.C.; Oostra, B.A.; Duijn, C.M. van
    In:European Journal of Human Genetics, 17, 958 - 966. ISSN 1018-4813.

    Samenvatting:

    Attention deficit/hyperactivity disorder (ADHD) is a common, highly heritable, neuropsychiatric disorder among children. Linkage studies in isolated populations have proved powerful to detect variants for complex diseases, such as ADHD. We performed a genome-wide linkage scan for ADHD in nine patien

  • Intrauterine Cannabis Exposure Affects Fetal Growth Trajectories: The Generation R Study (2009)

    Auteurs:Marroun, H. el; Tiemeier, H.; Steegers, E.A.P.; Jaddoe, V.W.V.; Hofman, A.; Verhulst, F.C.; Brink, W. van den; Huizink, A.C.
    In:Journal of the American Academy of Child & Adolescent Psychiatry, 48, 1173 - 1181. ISSN 0890-8567.

    Samenvatting:

    Objective: Cannabis is the most commonly consumed illicit drug among pregnant women. Intrauterine exposure to cannabis may result in risks for the developing fetus. The importance of intrauterine growth on subsequent psychological and behavioral child development has been demonstrated. This study ex

  • Temperamental Risk Factors for Adolescent Cannabis Use: A Systematic Review of Prospective General Population Studies (2009)

    Auteurs:Creemers, H.E.; Verhulst, F.C.; Huizink, A.C.
    In:Substance Use & Misuse, 44, 1833 - 1854. ISSN 1082-6084.

    Samenvatting:

    In order to establish the evidence for prospective relationships between temperamental and personality indicators of behavioral undercontrol and adolescent cannabis use, we systematically searched relevant papers published through April 2008. We assessed and evaluated 14 studies, of which only 4 wer

  • Cohort profile: The Dutch 'TRacking Adolescents' individual lives' survey'; TRAILS (2008)

    Auteurs:Huisman, M. (Martijn); Oldehinkel, A.J. (Albertine); Winter, de A.F. (Andrea); Minderaa, R.B. (Ruud); Bildt, de A. (Annelies); Huizink, A.C. (Anja); Verhulst, F.C. (Frank); Ormel, J. (Johan Hans)
    In:International Journal of Epidemiology, 37(6), 1227 - 1235. ISSN 0300-5771.

  • What is spared by fetal brain-sparing? Fetal circulatory redistribution and behavioral problems in the general population (2008)Open access

    Auteurs:Roza, S.J. (Sabine); Steegers, E.A.P. (Eric); Verburg, B.O. (Bero Olof); Jaddoe, V.W.V. (Vincent); Moll, H.A. (Henriëtte); Hofman, A. (Albert); Verhulst, F.C. (Frank); Tiemeier, H. (Henning)
    In:American Journal of Epidemiology, 168(10), 1145 - 1152. ISSN 0002-9262.

    Samenvatting:

    Intrauterine growth restriction has been linked to infant behavioral problems. While typically only birth weight is examined, here the authors assessed fetal circulatory redistribution, also called the "brain-sparing effect," which is a fetal adaptive reaction to placental insufficiency. They aimed

  • Explaining Educational Inequalities in Preterm Birth. The Generation R Study (2008)Open access

    Auteurs:Jansen, P.W. (Pauline); Tiemeier, H. (Henning); Jaddoe, V.W.V. (Vincent); Hofman, A. (Albert); Steegers, E.A.P. (Eric); Verhulst, F.C. (Frank); Mackenbach, J.P. (Johan); Raat, H. (Hein)
    In:Archives of Disease in Childhood: an international peer-reviewed journal for health professionals and researchers covering conception to adolescence, 1 - 23. ISSN 0003-9888.

    Samenvatting:

    BACKGROUND: Although a low socioeconomic status has consistently been associated with an increased risk of preterm birth, little is known about the pathways through which socioeconomic disadvantage influences preterm birth. AIM: To examine mechanisms that might underlie the association between the e

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