Prof.dr. P.W.J.C. Serruys

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Erasmus University Rotterdam (463)

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Fluvastatin for prevention of cardiac events following successful first percutaneous coronary intervention: a randomized controlled trial (2002)Open access

Authors:	Meier, B. (Bernard); Miguel, C.M. (Carlos); Kokott, N. (Norbert); Puel, J. (Jacques); Vrolix, M.C. (Mathias); Branzi, A. (Angelo); Bertolami, M.C.; Jackson, G. (Graham); Strauss, B.H. (Bradley); Feyter, de P.J. (Pim); Serruys, P.W.J.C. (Patrick)
In:	J A M A: The Journal of the American Medical Association. ISSN 0098-7484.

Abstract:

CONTEXT: Percutaneous coronary intervention (PCI) is associated with excellent short-term improvements in ischemic symptoms, yet only three fifths of PCI patients at 5 years and one third of patients at 10 years remain free of major adverse cardiac events (MACE). OBJECTIVE: To determine whether trea

Intravascular ultrasound findings in the multicenter, randomized, double-blind RAVEL (RAndomized study with the sirolimus-eluting VElocity balloon- expandable stent in the treatment of patients with de novo native coronary artery Lesions) trial (2002)Open access

Authors:	Ligthart, J.M.R. (Jürgen); Morice, M-C. (Marie-Claude); Feyter, de P.J. (Pim); Degertekin, M. (Muzaffer); Tanabe, K. (Kengo); Sousa, J.E. (Eduardo); Colombo, A. (Antonio); Guagliumi, G. (Giulio); Wijns, W. (William); Lindeboom, W.K. (Wietze); Serruys, P.W.J.C. (Patrick); Abizaid, A.C. (Alexandre)
In:	Circulation (Baltimore), 106(7), 798 - 803. ISSN 0009-7322.

Abstract:

BACKGROUND: The goal of this intravascular ultrasound investigation was to provide a more detailed morphological analysis of the local biological effects of the implantation of a sirolimus-eluting stent compared with an uncoated stent. METHODS AND RESULTS: In the RAVEL trial, 238 patients with singl

Results of Prevention of REStenosis with Tranilast and its Outcomes (PRESTO) trial (2002)Open access

Authors:	Holmes, D.R. (David); Granett, J.R. (Jeffrey); Popma, J.J. (Jeffrey); Fitzgerald, P.J. (Peter); Fischman, D. (David); Ferguson, J.J. (James); Lincoff, A.M. (Michael); Goldberg, S. (Sheldon); Brinker, J.A.; Chan, R.; Davis, B.R. (Barry); Poland, M.; Zeiher, A.M. (Andreas); Willerson, J.T. (James); King, S.B. (Spencer); Shapiro, L.M.; Savage, M. (Michael); Lablanche, J.M. (Jean Marc); Tcheng, J.E. (James); Grip, L. (Lars); Serruys, P.W.J.C. (Patrick)
In:	Circulation (Baltimore), 106(10), 1243 - 1250. ISSN 0009-7322.

Authors:

Holmes, D.R. (David); Granett, J.R. (Jeffrey); Popma, J.J. (Jeffrey); Fitzgerald, P.J. (Peter); Fischman, D. (David); Ferguson, J.J. (James); Lincoff, A.M. (Michael); Goldberg, S. (Sheldon); Brinker, J.A.; Chan, R.; Davis, B.R. (Barry); Poland, M.; Zeiher, A.M. (Andreas); Willerson, J.T. (James); King, S.B. (Spencer); Shapiro, L.M.; Savage, M. (Michael); Lablanche, J.M. (Jean Marc); Tcheng, J.E. (James); Grip, L. (Lars); Serruys, P.W.J.C. (Patrick)

In:

Circulation (Baltimore), 106(10), 1243 - 1250. ISSN 0009-7322.

Abstract:

BACKGROUND: Restenosis after percutaneous coronary intervention (PCI) is a major problem affecting 15% to 30% of patients after stent placement. No oral agent has shown a beneficial effect on restenosis or on associated major adverse cardiovascular events. In limited trials, the oral agent tranilast

Persistent inhibition of neointimal hyperplasia after sirolimus-eluting stent implantation: long-term (up to 2 years) clinical, angiographic, and intravascular ultrasound follow-up (2002)Open access

Authors:	Degertekin, M. (Muzaffer); Popma, J.J. (Jeffrey); Tanabe, K. (Kengo); Vos, J.R. (Jeroen); Brand, van den M.J.B.M. (Marcel); Feyter, de P.J. (Pim); Serruys, P.W.J.C. (Patrick); Foley, D.P. (David); Giessen, van der W.J. (Wim); Smits, P.C. (Pieter); Regar, E.S. (Eveline)
In:	Circulation (Baltimore), 106(13), 1610 - 1613. ISSN 0009-7322.

Abstract:

BACKGROUND: Early results of sirolimus-eluting stent implantation showed a nearly complete abolition of neointimal hyperplasia. The question remains, however, whether the early promising results will still be evident at long-term follow-up. The objective of our study was to evaluate the efficiency o

Non-invasive coronary angiography with multislice spiral computed tomography: impact of heart rate (2002)Open access

Authors:	Rensing, B.J.W.M. (Benno); Geuns, van R-J.M. (Robert-Jan); Vos, J.R. (Jeroen); Pattynama, P.M.T. (Peter); Krestin, G.P. (Gabriel); Feyter, de P.J. (Pim); Serruys, P.W.J.C. (Patrick); Nieman, K. (Koen)
In:	Heart, 88(5), 470 - 474. ISSN 1355-6037.

Abstract:

OBJECTIVE: To evaluate the impact of heart rate on the diagnostic accuracy of coronary angiography by multislice spiral computed tomography (MSCT). DESIGN: Prospective observational study. PATIENTS: 78 patients who underwent both conventional and MSCT coronary angiography for suspi

Rapamycin eluting stent: the onset of a new era in interventional cardiology (2002)Open access

Authors: Carter, A.J.; Serruys, P.W.J.C. (Patrick); Regar, E.S. (Eveline)
In: Heart, 87(4), 205 - 207. ISSN 1355-6037.

Authors:	Carter, A.J.; Serruys, P.W.J.C. (Patrick); Regar, E.S. (Eveline)
In:	Heart, 87(4), 205 - 207. ISSN 1355-6037.

Intracoronary beta-radiation to reduce restenosis after balloon angioplasty and stenting; the Beta Radiation In Europe (BRIE) study (2002)Open access

Authors:	Disco, C. (Clemens); Silber, S. (Sigmund); Debbas, N.; Bonnier, J.J.R.M. (Hans); Urban, P. (Philip); Wijns, W. (William); Benit, E. (Edouard); Vandormael, M.; Dorr, R.; Serruys, P.W.J.C. (Patrick); Giessen, van der W.J. (Wim); Sianos, G. (Georgios)
In:	European Heart Journal. ISSN 0195-668x.

Abstract:

AIMS: The BRIE trial is a registry evaluating the safety and performance of (90)Sr delivered locally (Beta-Cath TM system of Novoste) to de-novo and restenotic lesions in patients with up to two discrete lesions in different vessels. METHODS AND RESULTS: In total, 149 patients (175 lesions) were enr

Percutaneous valve implantation: back to the future? (2002)Open access

Authors: Herwerden, van L.A. (Lex); Serruys, P.W.J.C. (Patrick)
In: European Heart Journal. ISSN 0195-668x.

Authors:	Herwerden, van L.A. (Lex); Serruys, P.W.J.C. (Patrick)
In:	European Heart Journal. ISSN 0195-668x.

Platelet GP IIb/IIIa receptor blockers for failed thrombolysis in acute myocardial infarction, alone or as adjunct to other rescue therapies; single centre retrospective analysis of 548 consecutive patients with acute myocardial infarction (2002)Open access

Authors:	Ronner, E. (Eelko); Feyter, de P.J. (Pim); Simoons, M.L. (Maarten); Brand, van den M.J.B.M. (Marcel); Serruys, P.W.J.C. (Patrick); Foley, D.P. (David); Giessen, van der W.J. (Wim); Domburg, van R.T. (Ron)
In:	European Heart Journal. ISSN 0195-668x.

Abstract:

In order to study the safety of 'rescue' strategies in the treatment of patients with failed thrombolysis, all 548 patients admitted with evolving myocardial infarction to the Thoraxcenter, Rotterdam, from January 1997 until April 1999 were reviewed. Of these patients, 49% had received thrombolysis.

The TRAPIST Study. A multicentre randomized placebo controlled clinical trial of trapidil for prevention of restenosis after coronary stenting, measured by 3-D intravascular ultrasound. (2001)Open access

Authors:	Serruys, P.W.J.C. (Patrick); Foley, D.P. (David); Pieper, M. (Michael); Kleijne, J.A.; Feyter, de P.J. (Pim)
In:	European Heart Journal, 22(20), 1938 - 1947. ISSN 0195-668x.

Abstract:

BACKGROUND: Studies have reported benefit of oral therapy with the phosphodiesterase inhibitor, trapidil, in reducing restenosis after coronary angioplasty. Coronary stenting is associated with improved late outcome compared with balloon angioplasty, but significant neointimal hyperplasia still occu

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