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Prof.dr. P.W.J.C. Serruys Persoon

Prof.dr. P.W.J.C. Serruys

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  • Effects of the direct lipoprotein-associated phospholipase A2 inhibitor darapladib on human coronary atherosclerotic plaque (2008)

    Auteurs:Serruys, P.W.J.C. (Patrick); Garcia-Garcia, H.M. (Hector); Buszman, P. (Pawel); Erne, P. (Paul); Verheye, S. (Stefan); Aschermann, M. (Michael); Duckers, H.J. (Henricus); Bleie, O. (Oyvind); Dudek, D. (Dariusz); Bøtker, H.E.; Birgelen, von C. (Clemens); D'Amico, D. (Don); Hutchinson, T. (Tammy); Zambanini, A. (Andrew); Mastik, F. (Frits); Es, van G.A. (Gerrit Anne); Steen, van der A.F.W. (Ton); Vince, D.G. (Geoffrey); Ganz, P. (Peter); Hamm, C.W. (Christian); Wijns, W. (William); Zalewski, A. (Andrew)
    In:Circulation (Baltimore), 118(11), 1172 - 1182. ISSN 0009-7322.

    Samenvatting:

    Background - Lipoprotein-associated phospholipase A2 (Lp-PLA2) is expressed abundantly in the necrotic core of coronary lesions, and products of its enzymatic activity may contribute to inflammation and cell death, rendering plaque vulnerable to rupture. Methods and Results - This study compared the

  • Long-term safety and efficacy of percutaneous coronary intervention with stenting and coronary artery bypass surgery for multivessel coronary artery disease: A meta-analysis with 5-year patient-level data from the ARTS, ERACI-II, MASS-II, and SoS trials (2008)

    Auteurs:Daemen, J. (Joost); Boersma, H. (Eric); Flather, M. (Marcus); Booth, J. (Jean); Stables, R.H. (Rodney); Rodriguez, A. (Alfredo Chapin); Rodriguez-Granillo, G.A. (Gaston); Hueb, W.A. (Whady Armindo); Lemos, P.A. (Pedro); Serruys, P.W.J.C. (Patrick)
    In:Circulation (Baltimore), 118(11), 1146 - 1154. ISSN 0009-7322.

    Samenvatting:

    Background - Randomized trials that studied clinical outcomes after percutaneous coronary intervention (PCI) with bare metal stenting versus coronary artery bypass grafting (CABG) are underpowered to properly assess safety end points like death, stroke, and myocardial infarction. Pooling data from r

  • Late and very late stent thrombosis following drug-eluting stent implantation in unprotected left main coronary artery: A multicentre registry (2008)

    Auteurs:Chieffo, A. (Alaide); Park, S.J.; Meliga, E. (Emanuele); Sheiban, I. (Imad); Lee, M.S. (Michael); Latib, A. (Azeem); Kim, Y.H.; Valgimigli, M. (Marco); Sillano, D. (Dario); Magni, V. (Valeria); Biondi-Zoccai, G.G. (Giuseppe); Montorfano, M. (Matteo); Airoldi, F. (Flavio); Rogacka, R. (Renata); Carlino, M. (Mauro); Michev, I. (Iassen); Hong, M.K. (Myeong); Moretti, C. (Claudio); Bonizzoni, E. (Erminio); Sangiorgi, G.M. (Giuseppe); Tobis, J. (Jonathan); Serruys, P.W.J.C. (Patrick); Colombo, A. (Antonio)
    In:European Heart Journal, 29(17), 2108 - 2115. ISSN 0195-668x.

    Samenvatting:

    Aims: To evaluate the occurrence of late and very late stent thrombosis (ST) following elective drug-eluting stent (DES) implantation in unprotected left main coronary artery (LMCA) stenosis in a large multicentre registry. Methods and results: All 731 consecutive patients who had sirolimus- or pacl

  • Magnetically guided left ventricular lead implantation based on a virtual three-dimensional reconstructed image of the coronary sinus (2008)

    Auteurs:Rivero-Ayerza, M. (Maximo); Jessurun, E.; Ramcharitar, S. (Steve); Belle, van Y. (Yves); Serruys, P.W.J.C. (Patrick); Jordaens, L.J.L.M. (Luc)
    In:Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 10(9), 1042 - 1047. ISSN 1099-5129.

    Samenvatting:

    Aims: Left ventricular (LV) lead implantation is feasible using remote magnetic navigation of a guidewire (Stereotaxis, St Louis, MO, USA). A novel software that performs a three-dimensional (3D) reconstruction of vessels based on two or more angiographic views has been developed recently (CardiOp-B

  • Simulation of stent deployment in a realistic human coronary artery (2008)Open access

    Auteurs:Gijsen, F.J.H. (Frank); Migliavacca, F. (Francesco); Schievano, S. (Silvia); Socci, L. (Laura); Petrini, L. (Lorenza); Thury, A. (Attila); Wentzel, J.J. (Jolanda); Steen, van der A.F.W. (Ton); Serruys, P.W.J.C. (Patrick); Dubini, G. (Gabriele)
    In:BioMedical Engineering OnLine, 7. ISSN 1475-925x.

    Samenvatting:

    Background: The process of restenosis after a stenting procedure is related to local biomechanical environment. Arterial wall stresses caused by the interaction of the stent with the vascular wall and possibly stress induced stent strut fracture are two important parameters. The knowledge of these p

  • Optical coherence tomography assessment of vulnerable plaque rupture: Predilection for the plaque 'shoulder' (2008)

    Auteurs:Barlis, P. (Peter); Serruys, P.W.J.C. (Patrick); DeVries, A. (Arie); Regar, E.S. (Eveline)
    In:European Heart Journal, 29(16), 2023. ISSN 0195-668x.

  • Drug-eluting stents vs. coronary-artery bypass grafting (2008)

    Auteurs:Daemen, J. (Joost); Kukreja, N. (Neville); Serruys, P.W.J.C. (Patrick)
    In:New England Journal of Medicine, 358(24), 2641 - 2642. ISSN 0028-4793.

  • Four-year follow-up of treatment with intramyocardial skeletal myoblasts injection in patients with ischaemic cardiomyopathy (2008)

    Auteurs:Veltman, C.E. (Caroline); Soliman, O.I.I. (Osama Ibrahim Ibrahim); Geleijnse, M.L. (Marcel); Vletter, W.B. (Wim); Smits, P.C. (Pieter); Cate, ten F.J. (Folkert); Jordaens, L.J.L.M. (Luc); Balk, A.H.M.M. (Aggie); Serruys, P.W.J.C. (Patrick); Boersma, H. (Eric); Domburg, van R.T. (Ron); Giessen, van der W.J. (Wim)
    In:European Heart Journal, 29(11), 1386 - 1396. ISSN 0195-668x.

    Samenvatting:

    Aims: Studies reporting improved left ventricular (LV) function of percutaneous skeletal myoblast (SkM) injection in patients with ischaemic cardiomyopathy had follow-up not exceeding 12 months, and did not include a control group. Our group has reported evidence for myoblast efficacy in the first f

  • Feasibility of combined use of intravascular ultrasound radiofrequency data analysis and optical coherence tomography for detecting thin-cap fibroatheroma (2008)

    Auteurs:Sawada, T. (Takahiro); Shite, J. (Junya); Garcia-Garcia, H.M. (Hector); Shinke, T. (Toshiro); Watanabe, S. (Satoshi); Otake, H. (Hiromasa); Matsumoto, D. (Daisuke); Tanino, Y. (Yusuke); Ogasawara, D. (Daisuke); Kawamori, H. (Hiroyuki); Kato, H. (Hiroki); Miyoshi, N. (Naoki); Yokoyama, M. (Mitsuhiro); Serruys, P.W.J.C. (Patrick); Hirata, K.I.
    In:European Heart Journal, 29(9), 1136 - 1146. ISSN 0195-668x.

    Samenvatting:

    Aims: To evaluate the feasibility of the combined use of virtual histology (VH)-intravascular ultrasound (IVUS) and optical coherence tomography (OCT) for detecting in vivo thin-cap fibroatheroma (TCFA). Methods and results: In 56 patients with angina, 126 plaques identified by IVUS findings were an

  • Rapamycin modulates the eNOS vs. shear stress relationship (2008)

    Auteurs:Cheng, K.L. (Caroline); Tempel, D. (Dennie); Oostlander, A. (Angela); Helderman, F.; Gijsen, F.J.H. (Frank); Wentzel, J.J. (Jolanda); Haperen, van R. (Rien); Haitsma, D.B.; Serruys, P.W.J.C. (Patrick); Steen, van der A.F.W. (Ton); Crom, de M.P.G. (Rini); Krams, R. (Rob)
    In:Cardiovascular Research, 78(1), 123 - 129. ISSN 0008-6363.

    Samenvatting:

    Aims: Studies in animals and patients indicate that rapamycin affects vasodilatation differently in outer and inner curvatures of blood vessels. We evaluated in this study whether rapamycin affects endothelial nitric oxide synthase (eNOS) responsiveness to shear stress under normo- and hypercholeste

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