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abstractBackground: Children with Prader-Willi syndrome (PWS) have abnormal body composition and impaired growth. Short-term GH treatment has beneficial effects. Objectives: The aim of the study was to investigate effects of long-term continuous GH treatment on body composition, growth, bone maturat
abstractContext: The annual death rate of Prader-Willi syndrome (PWS) patients is very high (3%). Many of these deaths are sudden and unexplained. Objective: Because most deaths occur during moderate infections and PWS patients suffer from various hypothalamic insufficiencies, we investigated whethe
abstractThis thesis presents a detailed description of several studies on growth, metabolism, psychomotor development, cognition, behaviour and breathing in PWS children. In chapter 2, growth, body composition and body proportions before and during growth hormone (GH) treatment are evaluated.
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