KNAW

Prof.dr. W.M. de Vos
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Prof.dr. W.M. de Vos

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Completed research projects

(the most recent research is at the top)
Supervisor A. muciniphila transcriptome dynamics in medium and the gut environment.
Supervisor Optimizing growth rate, biomass and product formation of Lactococcus lactis by a systems biology approach.
Supervisor GeneNet: System dynamic analysis of gene networks in fungal systems.
Supervisor Genome mining and expression profiling of intestinal commensals
Supervisor Biocatalytic production of specific oligosaccharides
Supervisor Functionallity of the gastrointestinal tract.
Supervisor Elucidation of relationships between protozoa, L. pneumophila and biofilm concentrations in tap water installations
Supervisor Microbial CO conversion to H2 as a biological alternative for the chemical shift reaction
Supervisor CcpA and the regulation of lactose metabolism in Streptococcusthermophilus
Supervisor Mannitol production by lactic acid bacteria
Supervisor Engineering of microbial functionality; electrotransport C-008-ETP
Project leader Engineering of microbial functionality; electrotransport C-008-ETP
Supervisor Biodiversity and Mixed Cultures
Project leader Biodiversity and Mixed Cultures
Supervisor In situ gene expression of Lactobacillus in the GI tract
Supervisor Microbial food preservation and safety. Listeria monocytogenes stress response
Supervisor Vitamin B12 engineering in lactid acid bacteria
Supervisor Monitoring the genome wide impact of metabolic engineering of folate biosynthesis in Lb.plantanum - WCFS1
Supervisor The role of thioredoxin in L.Plantarum - WCFS1
Supervisor Communication and competition between grampositive bacteria that produce peptide pheromones in the gastro-intestinal tract
Supervisor Effect of trace elements on the metabolism of anaerobic micro-organisms in bioreactors
Supervisor Reconstruction of the regulatory network for Lactobacillus plantarum- WCFS1
Supervisor In situ gene expression Lactobacillus - WCFS1 in the GI-tract
Supervisor Microbial diversity of animal GI-tract
Supervisor Directed host response modulations
Supervisor Production of subtilases from hyperthermophilic microorganisms: a feasibility study
Supervisor Resilience of the groundwater ecosystem in reaction to anthropogenic disturbances
Supervisor Functional assessment of interactions between the human gut microbiota and the host
Supervisor Interaction between commensal bifidobacteria and diet and human intestinal tract
Supervisor Development and application of high throughput molecular methods for studying human gut microbiota in relation to diet and health
Project leader Development and application of high throughput molecular methods for studying human gut microbiota in relation to diet and health
Supervisor Comparative and predictive transcriptone analysis of the lactic acid bacterium Lactonacillus plantarum: identification and characterisation of global regulatory networks
Supervisor Interaction between commensal bifidobacteria and diet and human intestinal tract: An integrated genomes approach towards gut health
Supervisor Functional analysis of microbial activity and interactions in the GI-tract
Supervisor Functional microbiomics of the gastro-intestinal tract
Project leader Functional microbiomics of the gastro-intestinal tract
Supervisor High Cell Density Stress regulation of Lactobacillus plantarum
Supervisor Structure and function of microbial communities in river ecosystems in response to global environmental changes and pollution
Project leader Microbial aspects of anaerobic sulphate reduction with methane as electron donor
Supervisor Functional diversity and activity of microbial communities in response to changing environmental conditions
Supervisor Ecogenomics approaches to assess the bioremediation capacity of soils
Project leader Biocatalysis under influence of high pressure and microwave irradiation
Supervisor Gene expression analysis of Aspergillus oryzae and solid-state fermentations
Supervisor Comparative Metabolomics of Lactic Acid Bacteria
Supervisor Functionality of the pig gastrointestinal microbiota in response to alternatives for in-feed antimicrobials
Supervisor Pure culture stability and non-GMO functional strain improvement
Supervisor Revival of butanol production by Clostridia
Supervisor Microarray analysis to unravel Microbial Metabolism
Supervisor GI-tract specific gene expression in Lactobacillus plantanum - WCFS1
Project leader Diversity and antimicrobial activity of lactic acid bacteria in traditional fermented foods in Vietnam
Supervisor Microbe-mediated gut metabolism
Project leader Microbial functionality and safety
Supervisor Exploration of Genomic and Metabolite Diversity of a Novel Group of Abundant Soil Bacteria
Project leader The role of sigma factors in the stress-response of Bacillus cereus
Supervisor The role of sigma factors in the stress-response of Bacillus cereus
Project leader Initial events involved in germination of foodborne Bacillus cereus and inactivation of germinating spores and vegetative cells
Supervisor Initial events involved in germination of foodborne Bacillus cereus and inactivation of germinating spores and vegetative cells
Supervisor Germination of meophilic and psychrotophic foodborne Bacillus cereus
Supervisor Comparative and predictive transcriptome analysis of gram-positive bacteria for enhanced food functionality, food quality and food safety
Supervisor Biochemoprevention of colorectal neoplasia: interactions between plant foods and polymorphisms in coding as well as regulatory DNA sequences
Supervisor Optimization of catalytic features and production of thermozymes
Supervisor Nitrogen heterocycles from aldehydes via biocatalytic systems
Supervisor Engineering of Biosensors for Sugar Detection
Project leader Engineering of Biosensors for Sugar Detection
Supervisor Computational genomics of prokaryotes
Supervisor Novel bioreductions by hyperthermophilic microorganisms for the natural, specific and on-line production of fine chemicals (PYRED project)
Supervisor Molecular analysis of a novel dechlorinating biocatalyst
Supervisor Functional genomics of hyperthermophilic Archaea
Supervisor Biodegradation of benzene and aromatic intermediates under different redox concentrations
Supervisor Microbial aspects of mesophilic sulfate reduction in anaerobic bioreactors
Supervisor Physiological, biochemical and ecological aspects of chlorate-reducing bacteria, and their occurrence and distribution in the environment
Supervisor Fluorescent and molecular techniques for the assessment of the metabolic activity and indentification of colon microorganisms.
Supervisor Competition for the electron donors hydrogen and formate in in situ dehalogenation processes.
Supervisor Molecular monitoring of microbial diversity in anaerobic wastewater treatment
Project leader Enzymology and bioenergetics of the glycolytic pathway of Pyrococcus furiosus

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